☆ 4.6 Review

Contributions of Adaptive Laboratory Evolution towards the Enhancement of the Biotechnological Potential of Non-Conventional Yeast Species

JOURNAL OF FUNGI (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Agricultural Engineering

Rice straw-derived lipid production by HMF/furfural-tolerant oleaginous yeast generated by adaptive laboratory evolution

Gwon Woo Park et al.

Summary: Research on producing medium-and long-chain hydrocarbons as drop-in biofuels has accelerated recently. Lipids are emerging as precursors for biofuel production, and microbial lipid production utilizing agrowastes is becoming feasible. However, microorganisms are often inhibited by furan aldehydes in biomass hydrolysates. This study aimed to develop oleaginous yeast strains that can tolerate furan aldehydes for producing lipids as biofuel precursors. The evolved strain showed a higher growth rate and lipid production in the presence of furan aldehydes, providing insights into feasible strategies for producing drop-in biofuels from agrowastes.

BIORESOURCE TECHNOLOGY (2023)

添加到收藏夹

Article Agricultural Engineering

Development of multiple inhibitor tolerant yeast via adaptive laboratory evolution for sustainable bioethanol production

Hemansi et al.

Summary: The adaptive laboratory evolution (ALE) improved thermotolerant ethanologenic yeast by increasing specific growth rate and fermentation efficiency in the presence of inhibitors. The adapted yeast showed enhanced ethanol production from sequential dilute acid-alkali pretreated sugarcane bagasse, making bioethanol production more sustainable with reduced cost and time.

BIORESOURCE TECHNOLOGY (2022)

添加到收藏夹

Article Energy & Fuels

Adaptive Laboratory Evolution for Multistress Tolerance, including Fermentability at High Glucose Concentrations in Thermotolerant Candida tropicalis

Koudkeo Phommachan et al.

Summary: The thermotolerant yeast Candida tropicalis X-17, adapted through repetitive long-term cultivation at increasing temperatures and high glucose concentration, showed improved fermentation ability and tolerance to ethanol, furfural, and hydroxymethylfurfural. Transcriptome analysis revealed up-regulation of genes related to glucose transport, stress response, and cell wall proteins. These findings suggest that the up-regulation of these genes contributes to the improved phenotype of the adapted strain.

ENERGIES (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive laboratory evolution and reverse engineering enhances autotrophic growth in Pichia pastoris

Thomas Gassler et al.

Summary: Synthetic biology offers multiple pathways for converting CO2 into biomass or bio-chemicals, reducing the unsustainable use of organic feedstocks that contribute to climate change. The use of industrial organisms like Pichia pastoris allows for the development of novel bioproduction platforms with reduced reliance on alternative food production resources. By rewiring the central carbon metabolism and utilizing reverse genetic engineering, it is possible to enhance the autotrophic growth of microbes and explore potential applications for producing value-added products using CO2.

METABOLIC ENGINEERING (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Improving Furfural Tolerance of Escherichia coli by Integrating Adaptive Laboratory Evolution with CRISPR-Enabled Trackable Genome Engineering (CREATE)

Yangyang Zheng et al.

Summary: This study demonstrated the accelerated evolution of E. coli for improved furfural tolerance by combining adaptive laboratory evolution (ALE) with CRISPR-enabled trackable genome engineering (CREATE) technology, resulting in significantly increased genetic diversity and functional diversity.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2022)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Advanced strategies and tools to facilitate and streamline microbial adaptive laboratory evolution

Yinan Wu et al.

Summary: Adaptive laboratory evolution (ALE), as a microbial engineering method mimicking natural selection to obtain desired microbes, has seen significant improvements in the past decade in terms of growth coupling, genotypic diversification, phenotypic selection, and genotype-phenotype mapping. The development of growth-coupling strategies and multiplexed automated culture platforms have expanded the applicability of ALE, while multi-omics analyses and multiplexed genetic engineering have promoted efficient knowledge mining.

TRENDS IN BIOTECHNOLOGY (2022)

添加到收藏夹

Article Microbiology

Evolutionary Adaptation by Repetitive Long-Term Cultivation with Gradual Increase in Temperature for Acquiring Multi-Stress Tolerance and High Ethanol Productivity in Kluyveromyces marxianus DMKU 3-1042

Sornsiri Pattanakittivorakul et al.

Summary: This study aims to develop multi-stress tolerant strains of Kluyveromyces marxianus through a novel evolutionary adaptation procedure called RLCGT, and to increase ethanol production at high temperatures. Four adapted strains showed increased tolerance to ethanol and other stress factors, as well as higher ethanol production at high temperatures. Possible mechanisms of stress tolerance in adapted strains were discussed based on genome and transcriptome analyses.

MICROORGANISMS (2022)

添加到收藏夹

Article Microbiology

Torulaspora delbrueckii Phenotypic and Metabolic Profiling towards Its Biotechnological Exploitation

Flavia Silva-Sousa et al.

Summary: Torulaspora delbrueckii is gaining importance in the wine industry for its beneficial effects on wine characteristics such as low volatile acidity production, increased release of aromatic compounds, and enhanced color intensity. Research on 40 different strains of T. delbrueckii showed that factors like high temperature, ethanol concentrations, and SO2 levels significantly affect the yeast's fermentative performance and growth.

JOURNAL OF FUNGI (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Evolutionary and reverse engineering in Saccharomyces cerevisiae reveals a Pdr1p mutation-dependent mechanism for 2-phenylethanol tolerance

Huili Xia et al.

Summary: By using adaptive laboratory evolution (ALE), researchers have discovered that mutations in the transcription factor Pdr1p significantly enhance the tolerance of Saccharomyces cerevisiae to 2-phenylethanol (2-PE). This mutation alters the ratio of fatty acids, intracellular ergosterol, and reactive oxygen species (ROS), leading to improved tolerance and potentially aiding in the synthesis of natural 2-PE. This study provides new insights into the mechanisms of 2-PE tolerance and highlights the importance of Pdr1p in yeast engineering.

MICROBIAL CELL FACTORIES (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Improvement of macrolactins production by the genetic adaptation of Bacillus siamensis A72 to saline stress via adaptive laboratory evolution

Yuman Gan et al.

Summary: In this study, we successfully engineered a mutant strain with enhanced macrolactins production using a self-made device and adaptive laboratory evolution technology. The mutant strain showed saline resistance and increased macrolactins production within 60 days. Amino acid metabolism was found to be involved in the production of macrolactins in the evolved strain. The identified hisD mutation played a crucial role in the improvement of macrolactins production. This research provides insights for future metabolic engineering strategies to improve the production of other antibiotics and toxic compounds.

MICROBIAL CELL FACTORIES (2022)

添加到收藏夹

Article Genetics & Heredity

Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole

Rebekah J. Kukurudz et al.

Summary: This study conducted the first in vitro experimental evolution of Candida albicans strains in a high level of posaconazole and found widespread cross-tolerance among triazole drugs. The study also highlighted that increases in drug tolerance can occur independently of drug resistance.

G3-GENES GENOMES GENETICS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Development of Hypertolerant Strain of Yarrowia lipolytica Accumulating Succinic Acid Using High Levels of Acetate

Vivek Narisetty et al.

Summary: This study demonstrates that Yarrowia lipolytica can utilize acetate as a carbon source for growth and accumulate succinic acid. Through adaptive laboratory evolution, the recombinant strain showed improved tolerance and efficiency in utilizing acetate to produce succinic acid. Cofermentation of acetate and glucose further increased the production of succinic acid and lipids.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2022)

添加到收藏夹

Review Microbiology

Recent Advances in Directed Yeast Genome Evolution

Zhen Yao et al.

Summary: As a safe fungus widely used in industrial applications and basic research, Saccharomyces cerevisiae still faces challenges in improving desired traits and linking genotypes to phenotypes. Genome editing and evolutionary technology have rapidly developed to facilitate the generation of tailor-made properties and the determination of gene targets. Directed genome evolution has emerged as a versatile tool for accessing desired traits and studying complex phenomena.

JOURNAL OF FUNGI (2022)

添加到收藏夹

Article Biology

A streamlined strain engineering workflow with genome-wide screening detects enhanced protein secretion in Komagataella phaffii

Yoichiro Ito et al.

Summary: This study presents a method to improve protein production in the non-conventional yeast Komagataella phaffii. The method involves gene knockout screening, combining gene disruptions, and adaptive evolution to recover growth reduction. The researchers used a multiwell-formatted screening system to evaluate a large number of mutant strains and identified multiple gene disruptions that increased antibody production. They also found that the target protein and promoter could be interchangeable for the effects of gene knockouts. Adaptive evolution was used to recover reduced cell growth caused by multiple gene knockouts and explore the possibility of further enhancing protein secretion. The overall approach holds promise for improving protein production in non-conventional microorganisms.

COMMUNICATIONS BIOLOGY (2022)

添加到收藏夹

Article Biology

Genetic mechanisms underlying increased microalgal thermotolerance, maximal growth rate, and yield on light following adaptive laboratory evolution

Robin Barten et al.

Summary: Adaptive laboratory evolution (ALE) was used to optimize the green microalga Picochlorum sp. BPE23 towards supra-optimal temperature, resulting in mutant strains with increased maximal growth temperature and biomass yield. Genome sequencing and transcriptome analysis revealed 21 genic mutations and duplications in the mutants, providing insights into microalgal evolutionary mechanisms under abiotic stressors.

BMC BIOLOGY (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Reduced sensitivity of lager brewing yeast to premature yeast flocculation via adaptive evolution

Yang He et al.

Summary: Malt-induced premature yeast flocculation (PYF) is a sporadic problem in the brewing industry. This study used adaptive laboratory evolution (ALE) to improve the fermentation performance in PYF wort. The researchers obtained a variant yeast strain with improved fermentation properties and identified genetic changes related to the yeast's ability to remain in suspension during fermentation. The study suggests that ALE can attenuate yeast sensitivity to PYF malts over time.

FOOD MICROBIOLOGY (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Rational Metabolic Engineering Combined with Biosensor-Mediated Adaptive Laboratory Evolution for l-Cysteine Overproduction from Glycerol in Escherichia coli

Xiaomei Zhang et al.

Summary: This study successfully increased the production efficiency of l-cysteine by optimizing serine production, constructing a biosensor, and implementing adaptive laboratory evolution. The engineered strain achieved efficient biosynthesis of l-cysteine from glycerol conversion.

FERMENTATION-BASEL (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Induction of resistance mechanisms in Rhodotorula toruloides for growth in sugarcane hydrolysate with high inhibitor content

Helberth Junnior Santos Lopes et al.

Summary: This study compared colony selection and heterologous adaptive laboratory enhancement (ALE) strategies for obtaining robust strains of the oleaginous yeast Rhodotorula toruloides, and found that the ALE strategy resulted in higher maximum growth rate, biomass production, and lipid content. Additionally, colony selection strategy helped shorten the lag phase. Moreover, kinetics studies showed that acetic acid acts as a repressor of xylose consumption during R. toruloides cultivation.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Enhanced Tolerance of Spathaspora passalidarum to Sugarcane Bagasse Hydrolysate for Ethanol Production from Xylose

Thalyta F. Pacheco et al.

Summary: This study developed a more resistant yeast strain using adaptive laboratory evolution and central composite design methods, which can efficiently produce ethanol in hemicellulosic hydrolysate.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive laboratory evolution of Yarrowia lipolytica improves ferulic acid tolerance

Zedi Wang et al.

Summary: Yarrowia lipolytica strain was evolved through adaptive laboratory evolution to increase tolerance to ferulic acid, leading to a new strain with improved viability under high concentrations of ferulic acid, showing promise for application in lignocellulose conversion.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2021)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Learning from 80 years of studies: a comprehensive catalogue of non-Saccharomyces yeasts associated with viticulture and winemaking

Joao Drumonde-Neves et al.

Summary: Non-Saccharomyces yeast species have been recognized for their impact on wine chemical composition and sensorial properties. A systematic review of 80 years of literature identified 293 species isolated from grapes and grape musts, with a focus on yeast isolation from grapevines and damaged grapes. These yeast species have potential for diverse biotechnological applications.

FEMS YEAST RESEARCH (2021)

添加到收藏夹

Article Food Science & Technology

Thermo-adaptive evolution to generate improved Saccharomyces cerevisiae strains for cocoa pulp fermentations

Estefani Garcia-Rios et al.

Summary: This study aimed to generate robust S. cerevisiae strains by thermo-adaptive evolution for use in cocoa fermentation. The evolved strain showed genomic changes such as aneuploidies, segmental duplication, and SNVs, as well as alterations in membrane composition to maintain cell membrane state at high temperature. Experimental evolution proved to be an effective approach for generating better-adapted yeast strains for industrial processes at high temperature.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive laboratory evolution of β-caryophyllene producing Saccharomyces cerevisiae

Avinash Godara et al.

Summary: A combination of pathway engineering and adaptive laboratory evolution has successfully improved the production efficiency of beta-caryophyllene in an engineered yeast strain by leveraging the antioxidant potential of the compound. Using oxidative stress as selective pressure, the strain was able to achieve a fourfold increase in production within a few generations, with the best evolved mutant reaching a titer of 104.7 +/- 6.2 mg/L product.

MICROBIAL CELL FACTORIES (2021)

添加到收藏夹

Review Biochemical Research Methods

Genetic Diversity for Accelerating Microbial Adaptive Laboratory Evolution

Yangyang Zheng et al.

Summary: Adaptive laboratory evolution (ALE) is a widely used tool for improving microbial phenotypes by increasing genetic diversity through mutations. The construction of high-quality mutant libraries is crucial for the success of ALE, and technologies for generating genetic diversity have rapidly developed in recent years.

ACS SYNTHETIC BIOLOGY (2021)

添加到收藏夹

Review Microbiology

Biotechnological Importance of Torulaspora delbrueckii: From the Obscurity to the Spotlight

Ticiana Fernandes et al.

Summary: The study described the genomic, biochemical, and phenotypic features of Torulaspora delbrueckii and compared them with other species, particularly Saccharomyces cerevisiae. The research concludes that T. delbrueckii is a promising biotechnological model with potential applications in various industries, especially in wine and bakery. Additionally, a phylogenetic analysis using the core proteome of T. delbrueckii was conducted to understand its evolutionary placement, along with discussing available genetic tools for its improvement.

JOURNAL OF FUNGI (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica

Thomas Perli et al.

Summary: Engineering a new metabolic function in a microbial host can be limited by the availability of the relevant cofactor. In this study, the Moco biosynthesis pathway from Ogataea parapolymorpha was successfully transferred to Yarrowia lipolytica, enabling the synthesis of Moco and expression of a functional nitrate assimilation pathway. Through adaptive laboratory evolution, the activity of nitrate reductase increased significantly, leading to faster growth rates. This research demonstrates the potential for transferring the Moco pathway to distant yeasts, expanding the capabilities of industrial yeasts.

FEMS YEAST RESEARCH (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive evolution of sulfite tolerance in Brettanomyces bruxellensis

Caroline Bartel et al.

Summary: Studies have shown that the use of sulfur dioxide may lead to increased tolerance of Brettanomyces bruxellensis to sulfites, and exposure to sublethal sulfites can induce adaptive evolution in this yeast. This evolutionary process may involve the gene SSU1, which is associated with sulfite tolerance.

FEMS YEAST RESEARCH (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica

Thomas Perli et al.

Summary: This study established Molybdenum cofactor biosynthesis in Yarrowia lipolytica, expanding its nutrient range. The functionality of Moco was demonstrated, and fast growth on nitrate required adaptive laboratory evolution, resulting in increased nitrate reductase activity and growth rate. Genomic sequencing of evolved isolates revealed few mutations, suggesting successful transfer of the Moco pathway to distant yeasts.

FEMS YEAST RESEARCH (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2

Thomas Gassler et al.

NATURE BIOTECHNOLOGY (2020)

添加到收藏夹

Article Environmental Sciences

Enhancing succinic acid productivity in the yeast Yarrowia lipolytica with improved glycerol uptake rate

Khai Lun Ong et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2020)

添加到收藏夹

Review Food Science & Technology

Adaptive Laboratory Evolution of Ale and Lager Yeasts for Improved Brewing Efficiency and Beer Quality

B. Gibson et al.

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11 (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Improvement in d-xylose utilization and isobutanol production in S. cerevisiae by adaptive laboratory evolution and rational engineering

Peerada Promdonkoy et al.

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2020)

添加到收藏夹

Article Virology

Application of Adaptive Evolution to Improve the Stability of Bacteriophages during Storage

Kelvin K. Kering et al.

VIRUSES-BASEL (2020)

添加到收藏夹

Article Ecology

The omnistat: A flexible continuous-culture system for prolonged experimental evolution

David M. Ekkers et al.

METHODS IN ECOLOGY AND EVOLUTION (2020)

添加到收藏夹

Article Biochemical Research Methods

Automated Continuous Evolution of Proteins in Vivo

Ziwei Zhong et al.

ACS SYNTHETIC BIOLOGY (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Myriocin-induced adaptive laboratory evolution of an industrial strain of Saccharomyces cerevisiae reveals its potential to remodel lipid composition and heat tolerance

Francisca Randez-Gil et al.

MICROBIAL BIOTECHNOLOGY (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Assessment of ethanol tolerance ofKluyveromyces marxianusCCT 7735 selected by adaptive laboratory evolution

Fernando Augusto da Silveira et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

Patrick Phaneuf et al.

BMC GENOMICS (2020)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Current Status and Applications of Adaptive Laboratory Evolution in Industrial Microorganisms

SuRin Lee et al.

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

A mechanism-aware and multiomic machine-learning pipeline characterizes yeast cell growth

Christopher Culley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

添加到收藏夹

Article Microbiology

Adaptive Laboratory Evolution of Native Torulaspora delbrueckii YCPUC10 With Enhanced Ethanol Resistance and Evaluation in Co-inoculated Fermentation

Daniela Catrileo et al.

FRONTIERS IN MICROBIOLOGY (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Kluyveromyces marxianus developing ethanol tolerance during adaptive evolution with significant improvements of multiple pathways

Wenjuan Mo et al.

BIOTECHNOLOGY FOR BIOFUELS (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Development and genomic elucidation of hybrid yeast with improved glucose-xylose co-fermentation at high temperature

Yuping Lin et al.

FEMS YEAST RESEARCH (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Adaptive laboratory evolution of a genome-reduced Escherichia coli

Donghui Choe et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Ethanol production from water hyacinth (Eichhornia crassipes) hydrolysate by hyper-thermal acid hydrolysis, enzymatic saccharification and yeasts adapted to high concentration of xylose

InYung Sunwoo et al.

BIOPROCESS AND BIOSYSTEMS ENGINEERING (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive laboratory evolution of nanocellulose-producing bacterium

Vanessa M. Vasconcellos et al.

BIOTECHNOLOGY AND BIOENGINEERING (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Exceptional solvent tolerance in Yarrowia lipolytica is enhanced by sterols

Caleb Walker et al.

METABOLIC ENGINEERING (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Laboratory evolution strategies for improving lipid accumulation in Yarrowia lipolytica

Alexandra Daskalaki et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Experimental evolution: its principles and applications in developing stress-tolerant yeasts

Krishna B. S. Swamy et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae

Rui Pereira et al.

METABOLIC ENGINEERING (2019)

添加到收藏夹

Review Biotechnology & Applied Microbiology

The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology

Troy E. Sandberg et al.

METABOLIC ENGINEERING (2019)

添加到收藏夹

Article Green & Sustainable Science & Technology

Enhanced Ethanol Production from Sugarcane Bagasse Hydrolysate with High Content of Inhibitors by an Adapted Barnettozyma Californica

Hoda Nouri et al.

ENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY (2018)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Laboratory evolution reveals regulatory and metabolic trade-offs of glycerol utilization in Saccharomyces cerevisiae

Tomas Strucko et al.

METABOLIC ENGINEERING (2018)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System

Douglas McCloskey et al.

METABOLIC ENGINEERING (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

Identifying novel genetic determinants for oxidative stress tolerance in Candida glabrata via adaptive laboratory evolution

Mian Huang et al.

YEAST (2018)

添加到收藏夹

Article Agriculture, Multidisciplinary

Restoring of Glucose Metabolism of Engineered Yarrowia lipolytica for Succinic Acid Production via a Simple and Efficient Adaptive Evolution Strategy

Xiaofeng Yang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Microbial oil production in sugarcane bagasse hemicellulosic hydrolysate without nutrient supplementation by a Rhodosporidium toruloides adapted strain

Nemailla Bonturi et al.

PROCESS BIOCHEMISTRY (2017)

添加到收藏夹

Article Biochemical Research Methods

Biosensor-Enabled Directed Evolution to Improve Muconic Acid Production in Saccharomyces cerevisiae

John M. Leavitt et al.

BIOTECHNOLOGY JOURNAL (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

A Model for Designing Adaptive Laboratory Evolution Experiments

Ryan A. LaCroix et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Metabolic engineering and adaptive evolution for efficient production of D-lactic acid in Saccharomyces cerevisiae

Seung-Ho Baek et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Independent Evolution of Winner Traits without Whole Genome Duplication in Dekkera Yeasts

Yi-Cheng Guo et al.

PLOS ONE (2016)

添加到收藏夹

Article Biochemical Research Methods

Enhanced glutathione production by evolutionary engineering of Saccharomyces cerevisiae strains

Anett Patzschke et al.

BIOTECHNOLOGY JOURNAL (2015)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Evolutionary engineering of a wine yeast strain revealed a key role of inositol and mannoprotein metabolism during low-temperature fermentation

Maria Lopez-Malo et al.

BMC GENOMICS (2015)

添加到收藏夹

Review Food Science & Technology

Genetic improvement of non-GMO wine yeasts: Strategies, advantages and safety

Roberto Perez-Torrado et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2015)

添加到收藏夹

Article Genetics & Heredity

Adaptation to High Ethanol Reveals Complex Evolutionary Pathways

Karin Voordeckers et al.

PLOS GENETICS (2015)

添加到收藏夹

Article Biochemical Research Methods

Enhanced glutathione production by evolutionary engineering of Saccharomyces cerevisiae strains

Anett Patzschke et al.

BIOTECHNOLOGY JOURNAL (2015)

添加到收藏夹

Article Agricultural Engineering

Construction of reductive pathway in Saccharomyces cerevisiae for effective succinic acid fermentation at low pH value

Daojiang Yan et al.

BIORESOURCE TECHNOLOGY (2014)

添加到收藏夹

Article Biotechnology & Applied Microbiology

The enduring utility of continuous culturing in experimental evolution

David Gresham et al.

GENOMICS (2014)

添加到收藏夹

Article Food Science & Technology

Improved fermentation kinetics by wine yeast strains evolved under ethanol stress

Maite Novo et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Computational models reveal genotype-phenotype associations in Saccharomyces cerevisiae

Ricardo Franco-Duarte et al.

YEAST (2014)

添加到收藏夹

Review Microbiology

Improving industrial yeast strains: exploiting natural and artificial diversity

Jan Steensels et al.

FEMS MICROBIOLOGY REVIEWS (2014)

添加到收藏夹

Review Cell Biology

Microbial evolution in vivo and in silico: methods and applications

Vadim Mozhayskiy et al.

INTEGRATIVE BIOLOGY (2013)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Adaptive laboratory evolution - principles and applications for biotechnology

Martin Dragosits et al.

MICROBIAL CELL FACTORIES (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

James E. DiCarlo et al.

NUCLEIC ACIDS RESEARCH (2013)

添加到收藏夹

Article Biology

Evolutionary rescue and adaptation to abrupt environmental change depends upon the history of stress

Andrew Gonzalez et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2013)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture

Laura A. Bailey et al.

BIOTECHNOLOGY AND BIOENGINEERING (2012)

添加到收藏夹

Review Biochemistry & Molecular Biology

Evolutionary insight from whole-genome sequencing of experimentally evolved microbes

Jeremy R. Dettman et al.

MOLECULAR ECOLOGY (2012)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Genetically modified wine yeasts and risk assessment studies covering different steps within the wine making process

Manfred Grossmann et al.

ANNALS OF MICROBIOLOGY (2011)

添加到收藏夹

Review Biochemical Research Methods

Adaptive laboratory evolution - harnessing the power of biology for metabolic engineering

Vasiliy A. Portnoy et al.

CURRENT OPINION IN BIOTECHNOLOGY (2011)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Evolution-based strategy to generate non-genetically modified organisms Saccharomyces cerevisiae strains impaired in sulfate assimilation pathway

L. De Vero et al.

LETTERS IN APPLIED MICROBIOLOGY (2011)

添加到收藏夹

Review Biochemistry & Molecular Biology

Microbial laboratory evolution in the era of genome-scale science

Tom M. Conrad et al.

MOLECULAR SYSTEMS BIOLOGY (2011)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Evolutionary engineered Saccharomyces cerevisiae wine yeast strains with increased in vivo flux through the pentose phosphate pathway

Axelle Cadiere et al.

METABOLIC ENGINEERING (2011)

添加到收藏夹

Article Genetics & Heredity

Discovery of Mutations in Saccharomyces cerevisiae by Pooled Linkage Analysis and Whole-Genome Sequencing

Shanda R. Birkeland et al.

GENETICS (2010)

添加到收藏夹

Review Physiology

Microbial experimental evolution

Albert F. Bennett et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)

添加到收藏夹

Article Genetics & Heredity

Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

Anna M. Selmecki et al.

PLOS GENETICS (2009)

添加到收藏夹

Review Biochemistry & Molecular Biology

Comparative genomics of the environmental stress response in ascomycete fungi

Audrey P. Gasch

YEAST (2007)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Metabolic engineering of malolactic wine yeast

John I. Husnik et al.

METABOLIC ENGINEERING (2006)

添加到收藏夹

Review Cell Biology

The model organism as a system: integrating 'omics' data sets

AR Joyce et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

添加到收藏夹

Article Biotechnology & Applied Microbiology

In silico design and adaptive evolution of Escherichia coli for production of lactic acid

SS Fong et al.

BIOTECHNOLOGY AND BIOENGINEERING (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.