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Occurrence, Role, and Challenges of MicroRNA in Human Breast Milk: A Scoping Review

BIOMEDICINES (2023)

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Levels of Breast Milk MicroRNAs and Other Non-Coding RNAs Are Impacted by Milk Maturity and Maternal Diet

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Summary: Emerging evidence suggests that non-coding RNAs in maternal breast milk have unique effects on the metabolism and immune system of infants. This study provides the largest dataset of non-coding RNAs in breast milk and demonstrates a relationship between microRNAs in breast milk and maternal diet.

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Longitudinal Human Milk miRNA Composition over the First 3 mo of Lactation in a Cohort of Healthy Mothers Delivering Term Infants

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Detection and Quantification of Immunoregulatory miRNAs in Human Milk and Infant Milk Formula

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Human Milk Exosomal MicroRNA: Associations with Maternal Overweight/Obesity and Infant Body Composition at 1 Month of Life

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Summary: MicroRNA can be transferred from mother to infant via breast milk and potentially regulate the development of the infant's immune system. The study evaluated the efficiency of five RNA extraction kits from human skim milk samples, with one kit being found as the most appropriate for microRNA extraction. Further research is needed to establish a standardized protocol for microRNA extraction from breast milk.

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MiRNA-320a is less expressed and miRNA-148a more expressed in preterm human milk compared to term human milk

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Metabolism-related microRNAs in maternal breast milk are influenced by premature delivery

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Detection of long non-coding RNAs in human breastmilk extracellular vesicles: Implications for early child development

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Article Multidisciplinary Sciences

Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation

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Expressional analysis of immune-related miRNAs in breast milk

R. S. Na et al.

GENETICS AND MOLECULAR RESEARCH (2015)

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Human Milk MicroRNA and Total RNA Differ Depending on Milk Fractionation

Mohammed Alsaweed et al.

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MiRNA Analysis by Quantitative PCR in Preterm Human Breast Milk Reveals Daily Fluctuations of hsa-miR-16-5p

Ilaria Floris et al.

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Transcriptome Profiling of microRNA by Next-Gen Deep Sequencing Reveals Known and Novel miRNA Species in the Lipid Fraction of Human Breast Milk

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