4.6 Article

CCL20/CCR6 Mediated Macrophage Activation and Polarization Can Promote Adenoid Epithelial Inflammation in Adenoid Hypertrophy

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Review Immunology

CCR6-CCL20 axis as a therapeutic target for autoimmune diseases

Heikrujam Thoihen Meitei et al.

Summary: CCR6 and CCL20 play crucial roles in cell migration and inflammatory conditions, with strong associations found between their expression and disease severity in various autoimmune disorders. Targeting the CCR6-CCL20 axis shows promise in controlling autoimmune diseases by preventing immune cell migration and reducing inflammation.

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