Added Value of Ultrasound-Based Multimodal Imaging to Diagnose Hepatic Sclerosed Hemangioma before Biopsy and Resection

Imaging methods have the overwhelming advantage of being non-invasive in the diagnosis of hepatic lesions and, thanks to technical developments in the field of ultrasound (US), radiation exposure can also be avoided in many clinical situations. In particular, contrast-enhanced US (CEUS) outperforms other radiological methods in regard to real-time images, repeatability, and prompt reporting and demonstrates relatively few contraindications and adverse reactions. In this study, we reported in detail a rare benign tumor: hepatic sclerosed hemangioma (HSH). We described US-based multimodal imaging (B-flow imaging, US elastography, and Sonazoid CEUS) features of this HSH case. Furthermore, by summarizing the recently published literature on the imaging diagnosis of HSH, we offered readers comprehensive knowledge of conventional imaging methods (CT, MRI) and CEUS in the diagnosis of HSH and preliminarily discussed their mechanism of pathology-based diagnosis. Our multimodal imaging approach may provide a diagnostic strategy for HSH, thus avoiding unnecessary biopsy or resection.

Automated summary

Imaging methods, particularly contrast-enhanced ultrasound (CEUS), play a crucial role in the non-invasive diagnosis of hepatic lesions, providing real-time images, repeatability, and prompt reporting. In this study, we presented a detailed case of a rare benign tumor and described its features using multimodal imaging techniques. By summarizing recent literature, we provided comprehensive knowledge of conventional imaging methods and CEUS in the diagnosis of hepatic lesions, along with a preliminary discussion of their pathology-based diagnosis mechanism.