Staphylococcus Infection: Relapsing Atopic Dermatitis and Microbial Restoration

Article Dermatology

Mild to moderate atopic dermatitis severity can be reliably assessed using smartphone-photographs taken by the patient at home: A validation study

Zarqa Ali et al.

Summary: There is high agreement and reliability between photographic assessments and clinical evaluations of atopic dermatitis (AD) severity.

SKIN RESEARCH AND TECHNOLOGY (2022)

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Article Health Care Sciences & Services

German Mobile Apps for Patients With Psoriasis: Systematic Search and Evaluation

Christian Lull et al.

Summary: This study aimed to identify and evaluate the quality of current publicly available German apps for patients with psoriasis. The results showed heterogeneous app quality, with only a minority of the apps available in both app stores. Patient ratings of the apps were lower than those evaluated by healthcare professionals, emphasizing the importance of involving patients in the development and evaluation of health-related apps.

JMIR MHEALTH AND UHEALTH (2022)

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Review Pharmacology & Pharmacy

Flare management in atopic dermatitis: from definition to treatment

Giampiero Girolomoni et al.

Summary: Atopic dermatitis is a chronic-recurrent inflammatory skin disease. Acute exacerbations are a part of the disease course and require intensified treatment. Managing these exacerbations is crucial for long-term disease control, but there are difficulties and unclear aspects that need to be addressed.

THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2022)

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Article Infectious Diseases

Progress in Alternative Strategies to Combat Antimicrobial Resistance: Focus on Antibiotics

Jayaseelan Murugaiyan et al.

Summary: This review explores the development of new antimicrobial drugs and alternative strategies to traditional antibiotics. Various alternative approaches, including combination therapy, techniques targeting antimicrobial resistance enzymes or proteins, drug delivery systems, etc., are proposed as potential solutions.

ANTIBIOTICS-BASEL (2022)

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Article Immunology

Clinical efficacy of fecal microbial transplantation treatment in adults with moderate-to-severe atopic dermatitis

Jacob Mashiah et al.

Summary: The study suggests that fecal microbiota transplantation may be a safe and effective therapeutic intervention for atopic dermatitis, associated with the transfer of specific microbial species from donors to patients. Further studies are required to confirm these results.

IMMUNITY INFLAMMATION AND DISEASE (2022)

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Article Genetics & Heredity

The application of the skin virome for human identification

Ema H. Graham et al.

Summary: The stability and diversity of the human skin virome has been evaluated through a time series study across different body locations, leading to the identification of viral biomarkers that can be used for human identification and forensic applications.

FORENSIC SCIENCE INTERNATIONAL-GENETICS (2022)

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Review Biochemistry & Molecular Biology

Epigenetic Mechanisms of Epidermal Differentiation

Chiara Moltrasio et al.

Summary: Research has shown that the differentiation of keratinocytes is influenced by various transcription factors, signaling pathways, and epigenetic regulators, which promote differentiation by regulating chromatin modifications through activation and inhibition. Understanding the alterations in epigenetic mechanisms can facilitate their application in clinical practice, paving the way for promising therapeutic approaches.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Review Biotechnology & Applied Microbiology

Atopic dermatitis: an expanding therapeutic pipeline for a complex disease

Thomas Bieber

Summary: Recent advances in understanding of the complex phenotype and mechanisms underlying atopic dermatitis (AD) have revealed multiple new potential targets for pharmacological intervention. There are now more than 70 new compounds in development, in addition to regulatory approval for several inhibitors in Europe. The potential for a precision medicine approach to enable prevention and more effective long-term control of this complex disease is highlighted.

NATURE REVIEWS DRUG DISCOVERY (2022)

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Review Pharmacology & Pharmacy

Application of Nanomaterials in the Prevention, Detection, and Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA)

John Hulme

Summary: Experts have expressed concerns about a future surge in global antimicrobial resistance due to differences in geographic surveillance systems, chemical sanitization practices, and antibiotic stewardship during the COVID-19 pandemic. Researchers must develop alternative treatment tools to mitigate against an increase in pathogenic resistance.

PHARMACEUTICS (2022)

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Article Biochemistry & Molecular Biology

Limosilactobacillus reuteri Attenuates Atopic Dermatitis via Changes in Gut Bacteria and Indole Derivatives from Tryptophan Metabolism

Zhifeng Fang et al.

Summary: In this study, it was found that Limosilactobacillus reuteri DYNDL22M62 attenuated the symptoms of atopic dermatitis (AD) by modulating gut bacteria and the production of indole derivatives via activating the aryl hydrocarbon receptor (AHR) in mice.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Article Public, Environmental & Occupational Health

Effect of povidone-iodine and propanol-based mecetronium ethyl sulphate on antimicrobial resistance and virulence in Staphylococcus aureus

Nada A. Barakat et al.

Summary: This study evaluated the effect of povidone-iodine (PVP-I) and propanol-based mecetronium ethyl sulphate (PBM) on resistance development and virulence in Staphylococcus aureus. The results showed that PVP-I can effectively control the evolution of high-risk clones and inhibit virulence at subinhibitory concentrations. Special protocols need to be followed during PBM use to avoid the selection of resistant strains.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2022)

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Article Virology

Herpes Simplex Virus 1 Can Bypass Impaired Epidermal Barriers upon Ex Vivo Infection of Skin from Atopic Dermatitis Patients

Maureen Moeckel et al.

Summary: This study revealed the invasion process of herpes simplex virus 1 (HSV-1) in atopic dermatitis (AD) skin. The defective epidermal barriers of AD skin and inflammation-induced barrier defects make it easier for HSV-1 to enter skin cells.

JOURNAL OF VIROLOGY (2022)

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Review Cell Biology

Innovative Treatment Strategies to Accelerate Wound Healing: Trajectory and Recent Advancements

Praveen Kolimi et al.

Summary: This article provides an updated overview of progress in therapeutic options in chronic wounds healing and management using next generation innovative approaches. The authors discuss conventional treatment modalities as well as emerging strategies such as nanotherapeutics, stem cells therapy, and 3D bioprinting.

CELLS (2022)

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Review Biotechnology & Applied Microbiology

Advances in the human skin microbiota and its roles in cutaneous diseases

Yudie Yang et al.

Summary: This review provides insights into the interaction between human skin microbiota and human skin, the potential roles of microbiota in skin health and diseases, and the strategies for prevention, diagnosis, and treatment of microbe-related skin diseases.

MICROBIAL CELL FACTORIES (2022)

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Review Pharmacology & Pharmacy

The potential action of SSRIs in the treatment of skin diseases including atopic dermatitis and slow-healing wounds

Aneta Kiecka et al.

Summary: Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat affective and anxiety disorders, but they have also been found to have antimicrobial and immunomodulatory effects. Skin diseases such as atopic dermatitis (AD) and non-healing wounds present a significant medical challenge, and research on new drug groups is necessary to develop more effective treatments.

PHARMACOLOGICAL REPORTS (2022)

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Review Microbiology

The Role of the Cutaneous Mycobiome in Atopic Dermatitis

Milena Szczepanska et al.

Summary: Atopic dermatitis is a chronic inflammatory skin disorder characterized by eczematous lesions and itch. The changes in the fungal microbiome may play an important role in the pathogenesis of atopic dermatitis. This review summarizes the role of the cutaneous mycobiome in atopic dermatitis and new research possibilities in this field.

JOURNAL OF FUNGI (2022)

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Review Immunology

Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases

Yoshihiro Ito et al.

Summary: The skin serves as the interface between the human body and the environment, and its interaction with microbial communities plays a crucial role in maintaining skin health. Dysbiosis, or an imbalance in the microbial communities, can lead to various skin disorders. Recent developments in sequencing technology have provided new insights into the structure and function of skin microbial communities. Bacteriotherapy, the use of live bacteria as a therapeutic option, shows promise in treating cutaneous diseases caused by dysbiosis, but further exploration is needed to ensure its safety, efficacy, and sustainability.

INFLAMMATION AND REGENERATION (2022)

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Article Food Science & Technology

Staphylococcus aureus Extracellular Vesicles: A Story of Toxicity and the Stress of 2020

Xiaogang Wang et al.

Summary: Staphylococcus aureus generates and releases extracellular vesicles (EVs) containing toxins and other virulence factors that can affect host cells, with production influenced by various environmental stressors. Temperature and culture conditions have an impact on the production of EVs by S. aureus.

TOXINS (2021)

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Article Immunology

Staphylococcal Enterotoxin Superantigens Induce Prophylactic Antiviral Activity Against Encephalomyocarditis Virus In Vivo and In Vitro

Mustafa G. Mujtaba et al.

Summary: Staphylococcal enterotoxins, classified as superantigens, have potent immune activation and antiviral activity by inducing interferon gamma production. These superantigens could potentially be used for prophylactic treatment of viral infections and other pathologies requiring a robust immune response if their negative side effects can be eliminated.

VIRAL IMMUNOLOGY (2021)

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Article Microbiology

Environmental Plasticity of the RNA Content of Staphylococcus aureus Extracellular Vesicles

Brenda Silva Rosa Da Luz et al.

Summary: The study delved into the RNA content of Staphylococcus aureus EVs, revealing a diverse range of RNAs including those related to virulence and ribosomal proteins. The composition of EV RNAs was found to be significantly influenced by growth phase and environmental factors.

FRONTIERS IN MICROBIOLOGY (2021)

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Review Biochemistry & Molecular Biology

The complex, bidirectional role of extracellular vesicles in infection

Joni Renee White et al.

Summary: EVs play important roles in infection, acting both in defense against infection and potentially being hijacked by pathogens to enhance infection. EVs released by bacterial pathogens may deliver toxins, signaling molecules, and DNA, while also protecting infecting bacteria from immune killing.

BIOCHEMICAL SOCIETY TRANSACTIONS (2021)

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Article Microbiology

Temperature Influences the Composition and Cytotoxicity of Extracellular Vesicles in Staphylococcus aureus

Paul Briaud et al.

Summary: This study demonstrates that temperature variations during Staphylococcus aureus infection process can significantly impact the production, composition, and function of extracellular vesicles (EVs). Higher temperatures promote the packaging of virulence factors in EVs, while lower temperatures lead to increased toxicity towards macrophages. The findings highlight the importance of temperature-dependent interactions between EVs and host cells during S. aureus transition from colonization to virulence.

MSPHERE (2021)

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Article Nutrition & Dietetics

Processed Food and Atopic Dermatitis: A Pooled Analysis of Three Cross-Sectional Studies in Chinese Adults

Yajia Li et al.

Summary: Consumption of processed foods, including pickles and processed meats, is associated with increased risk of atopic dermatitis in Chinese adults.

FRONTIERS IN NUTRITION (2021)

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Article Multidisciplinary Sciences

Automated severity scoring of atopic dermatitis patients by a deep neural network

Chul Hwan Bang et al.

Summary: This study investigated the use of convolutional neural networks (CNNs) to assess the severity of atopic dermatitis (AD), and found that CNNs achieved high accuracy in evaluating erythema, papulation, excoriation, and lichenification, comparable to dermatologists.

SCIENTIFIC REPORTS (2021)

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Review Nanoscience & Nanotechnology

Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions

Yu Li et al.

Summary: Extracellular vesicles (EVs), containing DNAs, RNAs, lipids and proteins, have emerged as promising diagnostic and therapeutic agents for skin diseases. Summarizing the biological characteristics, applications, challenges and perspectives of EVs helps us better understand the potential of this novel therapy.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

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Article Multidisciplinary Sciences

The change of gut microbiota in MDD patients under SSRIs treatment

Yang Shen et al.

Summary: The study found that the gut microbiota of depressed patients tends to return to normal after treatment, but their metabolic function remains different from the control group.

SCIENTIFIC REPORTS (2021)

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Review Microbiology

Review: microbial transformations of human bile acids

Douglas V. Guzior et al.

Summary: Bile acids play key roles in gut metabolism, cell signaling, and microbiome composition. Microbes in the gut modify primary bile acids into diverse forms, and alterations in these secondary bile acids have been linked to various diseases. Recent studies have shown that gut microbiota can conjugate amino acids to bile acids, greatly increasing the diversity of bile acids in mammalian gut.

MICROBIOME (2021)

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Article Biochemistry & Molecular Biology

Gut microbiota restoration through fecal microbiota transplantation: a new atopic dermatitis therapy

Jong-Hwa Kim et al.

Summary: This study aimed to restore gut microbiota through fecal microbiota transplantation (FMT) to ameliorate atopic dermatitis (AD) in mice. FMT resulted in the restoration of gut microbiota, increased SCFA levels, restored Th1/Th2 balance, reduced allergic responses, and showed potential as a new therapy for AD.

EXPERIMENTAL AND MOLECULAR MEDICINE (2021)

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Review Food Science & Technology

Acrylamide in human diet, its metabolism, toxicity, inactivation and the associated European Union legal regulations in food industry

Agnieszka Koszucka et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)

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Article Dermatology

Eczema apps conformance with clinical guidelines: a systematic assessment of functions, tools and content

L. S. van Galen et al.

BRITISH JOURNAL OF DERMATOLOGY (2020)

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Article Multidisciplinary Sciences

Orchestration of human macrophage NLRP3 inflammasome activation by Staphylococcus aureus extracellular vesicles

Xiaogang Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

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Review Pharmacology & Pharmacy

Stress-induced Interaction of Skin Immune Cells, Hormones, and Neurotransmitters

Nives Pondeljak et al.

CLINICAL THERAPEUTICS (2020)

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Review Dermatology

The clinical significance of fungi in atopic dermatitis

Arsa Thammahong et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2020)

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Review Genetics & Heredity

Genetics and Epigenetics of Atopic Dermatitis: An Updated Systematic Review

Maria J. Martin et al.

GENES (2020)

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Review Biochemistry & Molecular Biology

Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis

Masutaka Furue

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Multidisciplinary Sciences

Unravelling the antimicrobial action of antidepressants on gut commensal microbes

Yasmina Ait Chait et al.

SCIENTIFIC REPORTS (2020)

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Article Immunology

Oral Administration of Acrylamide Worsens the Inflammatory Responses in the Airways of Asthmatic Mice Through Agitation of Oxidative Stress in the Lungs

Bahador Hajimohammadi et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Review Biochemistry & Molecular Biology

The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review

Mette S. Schjodt et al.

METABOLITES (2020)

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Review Dermatology

Genetics in Atopic Dermatitis: Historical Perspective and Future Prospects

Sara J. Brown et al.

ACTA DERMATO-VENEREOLOGICA (2020)

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Article Health Care Sciences & Services

Creating a Smartphone App for Caregivers of Children With Atopic Dermatitis With Caregivers, Health Care Professionals, and Digital Health Experts: Participatory Co-Design

Xiaomeng Xu et al.

JMIR MHEALTH AND UHEALTH (2020)

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Article Allergy

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

Emma Guttman-Yassky et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

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Review Medicine, Research & Experimental

Epithelial barrier repair and prevention of allergy

Elena Goleva et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

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Review Allergy

Staphylococcus aureus in atopic dermatitis: Strain-specific cell wall proteins and skin immunity

Kazumasa Iwamoto et al.

ALLERGOLOGY INTERNATIONAL (2019)

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Article Endocrinology & Metabolism

Topical Fluoxetine as a Novel Therapeutic That Improves Wound Healing in Diabetic Mice

Chuong Minh Nguyen et al.

DIABETES (2019)

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Review Infectious Diseases

Recent advances in the treatment of C. difficile using biotherapeutic agents

Vo Van Giau et al.

INFECTION AND DRUG RESISTANCE (2019)

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Article Cell Biology

MicroRNA-155-5p is a key regulator of allergic inflammation, modulating the epithelial barrier by targeting PKIα

Xiaoyu Wang et al.

CELL DEATH & DISEASE (2019)

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Article Allergy

A tryptophan metabolite of the skin microbiota attenuates inflammation in patients with atopic dermatitis through the aryl hydrocarbon receptor

Jinlei Yu et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

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Article Allergy

The microbiome in patients with atopic dermatitis

Amy S. Paller et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

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Review Chemistry, Medicinal

Recent advances in the treatment of pathogenic infections using antibiotics and nano-drug delivery vehicles

Vo Van Giau et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2019)

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Article Medicine, Research & Experimental

Conjugated bile acids attenuate allergen-induced airway inflammation and hyperresposiveness by inhibiting UPR transducers

Emily M. Nakada et al.

JCI INSIGHT (2019)

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Article Multidisciplinary Sciences

Gut microbiota profile in children affected by atopic dermatitis and evaluation of intestinal persistence of a probiotic mixture

Sofia Reddel et al.

SCIENTIFIC REPORTS (2019)

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Letter Dermatology

Methicillin-Resistant Staphylococcus aureus Colonization Is Associated with Decreased Skin Commensal Bacteria in Atopic Dermatitis

Baochen Shi et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2018)

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Article Immunology

Anti-Candida activity of antidepressants sertraline and fluoxetine: effect upon pre-formed biofilms

Ana S. Oliveira et al.

MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2018)

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Article Multidisciplinary Sciences

Microglial control of astrocytes in response to microbial metabolites

Veit Rothhammer et al.

NATURE (2018)

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Review Microbiology

The human skin microbiome

Allyson L. Byrd et al.

NATURE REVIEWS MICROBIOLOGY (2018)

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Review Allergy

Significance of Skin Barrier Dysfunction in Atopic Dermatitis

Byung Eui Kim et al.

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH (2018)

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Review Nutrition & Dietetics

Gut Microbiota and Their Neuroinflammatory Implications in Alzheimer's Disease

Vo Van Giau et al.

NUTRIENTS (2018)

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Review Biotechnology & Applied Microbiology

Interaction of gut microbiota with bile acid metabolism and its influence on disease states

Christopher Staley et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2017)

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Article Dermatology

Povidone-iodine ointment demonstrates in vitro efficacy against biofilm formation

Matthias J. Hoekstra et al.

INTERNATIONAL WOUND JOURNAL (2017)

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Article Dermatology

Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes

Michael R. Williams et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)

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Review Surgery

Povidone iodine in wound healing: A review of current concepts and practices

Paul Lorenz Bigliardi et al.

INTERNATIONAL JOURNAL OF SURGERY (2017)

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Article Dermatology

Efficacy and tolerability of liposomal polyvinylpyrrolidone-iodine hydrogel for the localized treatment of chronic infective, inflammatory, dermatoses: an uncontrolled pilot study

Matthias Augustin et al.

CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY (2017)

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Article Cell Biology

MicroRNA-124 alleviates chronic skin inflammation in atopic eczema via suppressing innate immune responses in keratinocytes

Zhibo Yang et al.

CELLULAR IMMUNOLOGY (2017)

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Review Biochemical Research Methods

Recent Advances in the Detection of Methicillin Resistant Staphylococcus aureus (MRSA)

John Hulme

BIOCHIP JOURNAL (2017)

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Article Dermatology

Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype

Magdalena Trzeciak et al.

ACTA DERMATO-VENEREOLOGICA (2017)

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Article Immunology

Skin-Specific Unsaturated Fatty Acids Boost the Staphylococcus aureus Innate Immune Response

Minh Thu Nguyen et al.

INFECTION AND IMMUNITY (2016)

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Letter Allergy

Staphylococcus aureus density on lesional and nonlesional skin is strongly associated with disease severity in atopic dermatitis

Marie Tauber et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

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Review Medicine, General & Internal

Atopic dermatitis

Stephan Weidinger et al.

LANCET (2016)

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Article Cell Biology

MicroRNA-143 inhibits IL-13-induced dysregulation of the epidermal barrier-related proteins in skin keratinocytes via targeting to IL-13Rα1

Yue-Ping Zeng et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2016)

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Correction Multidisciplinary Sciences

Aberrant Wound Healing in an Epidermal Interleukin-4 Transgenic Mouse Model of Atopic Dermatitis (vol 11, e0146451, 2016)

Yan Zhao et al.

PLOS ONE (2016)

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Review Allergy

Child with atopic dermatitis

Watcharoot Kanchongkittiphon et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2015)

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Article Dermatology

Galactomyces fermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manner

K. Takei et al.

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2015)

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Article Dermatology

Promoter demethylation contributes to TSLP overexpression in skin lesions of patients with atopic dermatitis

Y. Luo et al.

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2014)

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Article Allergy

MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes

Ana Rebane et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

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Article Dermatology

An Integrated Epigenetic and Transcriptomic Analysis Reveals Distinct Tissue-Specific Patterns of DNA Methylation Associated with Atopic Dermatitis

Elke Rodriguez et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)

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Article Biochemical Research Methods

Serum Metabolomics Study and Eicosanoid Analysis of Childhood Atopic Dermatitis Based on Liquid Chromatography-Mass Spectrometry

Yan Huang et al.

JOURNAL OF PROTEOME RESEARCH (2014)

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Article Multidisciplinary Sciences

An Important Role of α-Hemolysin in Extracellular Vesicles on the Development of Atopic Dermatitis Induced by Staphylococcus aureus

Sung-Wook Hong et al.

PLOS ONE (2014)

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Review Medicine, Research & Experimental

Staphylococcal Infections: Mechanisms of Biofilm Maturation and Detachment as Critical Determinants of Pathogenicity

Michael Otto

ANNUAL REVIEW OF MEDICINE, VOL 64 (2013)

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Article Allergy

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin

Laurence Pellerin et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

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Article Dermatology

Unfolded protein response in keratinocytes: Impact on normal and abnormal keratinization

K. Sugiura

JOURNAL OF DERMATOLOGICAL SCIENCE (2013)

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Letter Allergy

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue: a preliminary study

Claudina A. Perez-Novo et al.

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY (2013)

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Article Allergy

Staphylococcus aureus-derived extracellular vesicles induce neutrophilic pulmonary inflammation via both Th1 and Th17 cell responses

M. -R. Kim et al.

ALLERGY (2012)

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Article Allergy

Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

Julia K. Gittler et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

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Review Dermatology

One Remarkable Molecule: Filaggrin

Sara J. Brown et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)

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Review Biochemistry & Molecular Biology

T cell homing to epithelial barriers in allergic disease

Sabina A. Islam et al.

NATURE MEDICINE (2012)

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Article Medicine, Research & Experimental

Epigenetics and Bacterial Infections

Helene Bierne et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

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Article Dermatology

2,3,7,8-Tetrachlorodibenzo-p-dioxin alters sebaceous gland cell differentiation in vitro

Qiang Ju et al.

EXPERIMENTAL DERMATOLOGY (2011)

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Review Dermatology

A Retrospective Review of Streptococcal Infections in Pediatric Atopic Dermatitis

Jeffrey L. Sugarman et al.

PEDIATRIC DERMATOLOGY (2011)

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Article Allergy

Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema

J. M. Jungersted et al.

ALLERGY (2010)

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Article Multidisciplinary Sciences

Requirement of CCL17 for CCR7-and CXCR4-dependent migration of cutaneous dendritic cells

Susanne Stutte et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Article Allergy

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens

Tiffany C. Scharschmidt et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)

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Article Immunology

Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

Byung Eui Kim et al.

CLINICAL IMMUNOLOGY (2008)

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Article Biochemistry & Molecular Biology

n-3 Polyunsaturated fatty acids and atopy in Korean preschoolers

Inkyung Hwang et al.

LIPIDS (2007)

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Letter Medicine, General & Internal

Atopic dermatitis - a risk factor for invasive Staphylococcus aureus infections: Two cases and review

S Benenson et al.

AMERICAN JOURNAL OF MEDICINE (2005)

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Article Gastroenterology & Hepatology

Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?

PV Kirjavainen et al.

GUT (2002)

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Article Dermatology

The importance of disinfection therapy using povidone-iodine solution in atopic dermatitis

K Sugimoto et al.

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