4.3 Article

EFFECT OF ELECTRIC PULSE TREATMENT ON MICROSTRUCTURE, ELECTROCHEMICAL AND DISCHARGE PROPERTIES OF AZ61 ANODES FOR Mg-AIR BATTERIES

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ANNALS OF TRANSLATIONAL MEDICINE
卷 -, 期 -, 页码 -

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AME PUBLISHING COMPANY
DOI: 10.21037/atm-22-6423

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Mitochondrial unfolded protein response (UPRmt); bibliometric analysis; Web of Science (WOS); CiteSpace; VOSviewer

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This study conducted a bibliometric analysis on the mitochondrial unfolded protein response (UPRmt) and found that UPRmt research has gone through the stages of infancy and rapid growth. The United States and China have made the largest contributions to UPRmt research, with Harvard University being the most influential institution and Johan Auwerx and CM Haynes being the most prolific authors. The research areas of UPRmt mainly include biochemistry/molecular biology and cell biology. Strengthening cooperation and exchanges between countries, institutions, and authors will promote the development of this field.
Background: The mitochondrial unfolded protein response (UPRmt) is a mitochondria stress response, which exerts a crucial role in maintaining mitochondrial proteostasis during stress. However, there is no bibliometric analyses systematically studied this field which could comprehensively review research trends, evaluate publication performances and provide future perspectives.Methods: Articles investigating UPRmt published between 1994 and 2021 were downloaded from the Core Collection of the Web of Science (WOS). CiteSpace and VOSviewer bibliometric software were applied for bibliometric and visual analyses.Results: A total of 2,073 papers researching UPRmt were retrieved. According to the published number of papers, the field of UPRmt research has gone through its infancy (after 2000) and rapid growth (after 2021) phases. The United States and China contributed the most to UPRmt research. Regarding the distribution of institutions, Harvard University was the most influential institution. The most prolific authors are Johan Auwerx and CM Haynes. PLoS One is the most extensive journal in the field of UPRmt research, while the Cell Death and Differentiation journal had the greatest impact among the most-authored journals. Moreover, biochemistry/molecular biology, and cell biology are the largest subject areas. UPRmt research is mainly categorized as UPRmt, transcription, endoplasmic reticulum (ER) stress, lipotoxicity, mitophagy, mitochondrial permeability transition, and integrated stress response.Conclusions: At present, research on UPRmt is booming. Further strengthening the cooperation and exchanges between countries, institutions, and authors in the future will surely promote the development of this field.

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