4.6 Review

Probiotics in Periodontal and Peri-Implant Health Management: Biofilm Control, Dysbiosis Reversal, and Host Modulation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Dentistry, Oral Surgery & Medicine

Adjunctive probiotics after periodontal debridement versus placebo: a systematic review and meta-analysis

Ethan Ng et al.

Summary: The study found that adjunctive probiotics did not have added benefits for the total number of deep sites before and after therapy, but could reduce mean probing pocket depth, decrease the percentage of patients needing additional therapy, lower the risk of disease progression, and immunological outcomes were more consistent with clinical findings. No adverse events were reported.

ACTA ODONTOLOGICA SCANDINAVICA (2022)

Review Nutrition & Dietetics

The Clinical, Microbiological, and Immunological Effects of Probiotic Supplementation on Prevention and Treatment of Periodontal Diseases: A Systematic Review and Meta-Analysis

Zohre Gheisary et al.

Summary: The study demonstrated that probiotic supplementation has a positive effect on improving clinical parameters, reducing periodontopathogen load, and pro-inflammatory markers in patients with periodontal disease. Further research is needed to explore the preventive role of probiotic supplementation.

NUTRIENTS (2022)

Review Immunology

Do Probiotics Cause a Shift in the Microbiota of Dental Implants-A Systematic Review and Meta-Analysis

Shariel Sayardoust et al.

Summary: The systematic review and meta-analysis found that probiotics do not have a significant effect on implant microflora and do not provide any additional benefits in the non-surgical treatment of peri-implant mucositis and peri-implantitis.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2022)

Review Pharmacology & Pharmacy

The Use of Probiotics as Adjuvant Therapy of Periodontal Treatment: A Systematic Review and Meta-Analysis of Clinical Trials

Louis Hardan et al.

Summary: This study evaluated the use of probiotics as adjuvant therapy in the treatment of periodontal disease through a systematic review and meta-analysis. The results showed that probiotics improved periodontal pocket depth, clinical attachment loss, and bleeding on probing parameters, but had no significant effect on the index plaque parameter.

PHARMACEUTICS (2022)

Review Chemistry, Multidisciplinary

Inflammatory, Reactive, and Hypersensitivity Lesions Potentially Due to Metal Nanoparticles from Dental Implants and Supported Restorations: An Umbrella Review

Federica Di Spirito et al.

Summary: This umbrella review examined the prevalence and characteristics of lesions caused by dental implants and implant-supported restorations, focusing on the potential role of Titanium and other metal nanoparticles. The study found that peri-implant mucositis and peri-implantitis, reactive lesions, and hypersensitivity reactions were common types of lesions. However, investigations into Titanium allergy were limited and inconclusive.

APPLIED SCIENCES-BASEL (2022)

Editorial Material Chemistry, Multidisciplinary

Oral-Systemic Health and Disorders: Latest Prospects on Oral Antisepsis

Federica Di Spirito

APPLIED SCIENCES-BASEL (2022)

Editorial Material Chemistry, Multidisciplinary

Oral-Systemic Health and Disorders: Latest Advances on Oral-Gut-Lung Microbiome Axis

Alessandra Amato

APPLIED SCIENCES-BASEL (2022)

Article Health Care Sciences & Services

Adherence to Antibiotic Prescription of Dental Patients: The Other Side of the Antimicrobial Resistance

Francesco D'Ambrosio et al.

Summary: The study found that dental patients have low adherence to oral antibiotic therapy and have limited awareness of antimicrobial resistance (AMR). Education level and cohabitation status were found to affect treatment adherence, while age and gender had less impact.

HEALTHCARE (2022)

Article Health Care Sciences & Services

Attitudes towards Antibiotic Prescription and Antimicrobial Resistance Awareness among Italian Dentists: What Are the Milestones?

Francesco D'Ambrosio et al.

Summary: This study evaluates the attitude towards antibiotic prescribing and awareness of antimicrobial resistance among Italian dentists. The findings indicate a widespread problem of antibiotic misuse and overuse in Italy, with a low percentage of dentists consulting prescribing guidelines.

HEALTHCARE (2022)

Review Dentistry, Oral Surgery & Medicine

Evidence-based Recommendations on Periodontal Practice and the Management of Periodontal Patients During and After the COVID-19 Era: Challenging Infectious Diseases Spread by Airborne Transmission

Federica Di Spirito et al.

Summary: The study focuses on providing safe periodontal care and managing periodontal patients in the COVID-19 era. Recommendations include contamination control and ergonomic improvements, as well as suggestions to reduce emergency treatments and extend recall intervals in periodontal practice.

OPEN DENTISTRY JOURNAL (2021)

Review Dentistry, Oral Surgery & Medicine

Are probiotics a possible treatment of periodontitis? Probiotics against periodontal disease: a systematic review

Nuria Canut-Delgado et al.

Summary: Probiotics as an adjuvant treatment to periodontal therapy can effectively improve clinical parameters, reduce the concentration of periodontal pathogens, and have no side effects.

BRITISH DENTAL JOURNAL (2021)

Review Pharmacology & Pharmacy

Efficacy of Probiotics as Adjunctive Therapy to Nonsurgical Treatment of Peri-Implant Mucositis: A Systematic Review and Meta-Analysis

Rui Zhao et al.

Summary: The systematic review and meta-analysis concluded that the additional use of probiotics did not improve the efficacy of mechanical debridement (MD) in treating peri-implant mucositis (PiM) in terms of clinical and microbial outcomes in the short term.

FRONTIERS IN PHARMACOLOGY (2021)

Article Microbiology

Probiotic Alternative to Chlorhexidine in Periodontal Therapy: Evaluation of Clinical and Microbiological Parameters

Andrea Butera et al.

Summary: The study evaluated the use of two new formulations (toothpaste and chewing-gum) as support for periodontitis treatment. While probiotics showed benefits on certain clinical indexes and specific periodontopathogens, further research is needed to explore the relationship between probiotic colonization and improvement in clinical parameters.

MICROORGANISMS (2021)

Review Dentistry, Oral Surgery & Medicine

Host Modulation and Treatment of Periodontal Disease

M. G. Balta et al.

Summary: Periodontitis is the sixth-most prevalent disease in the world and the leading cause of tooth loss in adults. Recent studies have shown that synthetic and biological disease-modifying antirheumatic drugs, such as rituximab and tocilizumab, can improve periodontal clinical parameters. Probiotics and nutritional supplements have also been found to provide anti-inflammatory benefits in the treatment of periodontitis.

JOURNAL OF DENTAL RESEARCH (2021)

Review Dentistry, Oral Surgery & Medicine

Peri-implantitis is not periodontitis: Scientific discoveries shed light on microbiome-biomaterial interactions that may determine disease phenotype

Georgios A. Kotsakis et al.

Summary: Peri-implantitis is an immune-mediated complication attributed to bacterial biofilms on the implant surface. Revisiting its pathogenesis is necessary due to the lack of efficacy of antimicrobial treatments and recent discoveries from microbial studies.

PERIODONTOLOGY 2000 (2021)

Review Dentistry, Oral Surgery & Medicine

Microbial transitions from health to disease

Susan Joseph et al.

Summary: Recent advances in research on microbial populations in the human mouth provide new insights into the mechanisms underlying periodontal health and disease. The resilience of healthy and diseased microbial communities may be influenced by the genetics of the host and the makeup of the acquired microbiome.

PERIODONTOLOGY 2000 (2021)

Review Microbiology

Role of Gut Microbiota and Probiotics in Colorectal Cancer: Onset and Progression

Edgar Torres-Maravilla et al.

Summary: The gut microbiota is crucial for maintaining human health, and probiotics show promise as adjuvants for colorectal cancer treatment.

MICROORGANISMS (2021)

Article Dentistry, Oral Surgery & Medicine

Interdental and subgingival microbiota may affect the tongue microbial ecology and oral malodour in health, gingivitis and periodontitis

Abish S. Stephen et al.

Summary: Oral malodour is linked to periodontal diseases, with higher concentrations of volatile sulphur compounds found in patients with periodontitis. Differences in tongue microbiota were observed in relation to plaque accumulation, suggesting a potential connection between tongue and periodontal health.

JOURNAL OF PERIODONTAL RESEARCH (2021)

Review Dentistry, Oral Surgery & Medicine

CLINICAL EFFICACY OF PROBIOTICS AS AN ADJUNCTIVE THERAPY TO SCALING AND ROOT PLANNING IN THE MANAGEMENT OF PERIODONTITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRAILS

Daoyong Hu et al.

Summary: The study results indicate that probiotics as adjunctive therapy to scaling and root planning treatment can effectively improve clinical outcomes in the management of periodontitis, and also improve plaque and gingival index in the short term. However, further research is needed to confirm long-term efficacy.

JOURNAL OF EVIDENCE-BASED DENTAL PRACTICE (2021)

Review Microbiology

Infective Endocarditis: A Focus on Oral Microbiota

Carmela Del Giudice et al.

Summary: Infective endocarditis is an inflammatory disease caused by bacteria, and prevention and improvement of oral hygiene are important strategies. The oral microbiota may be one of the significant risk factors for infection.

MICROORGANISMS (2021)

Review Dentistry, Oral Surgery & Medicine

Periodontal and Peri-Implant Diseases and Systemically Administered Statins: A Systematic Review

Federica Di Spirito et al.

Summary: Hyperlipidemia and periodontitis are interrelated, and treatment of one condition may have a positive impact on the other. Statins may benefit periodontal and peri-implant tissues, but the evidence is inconclusive, necessitating further research.

DENTISTRY JOURNAL (2021)

Article Dentistry, Oral Surgery & Medicine

Possible Association of Periodontal Disease and Macular Degeneration: A Case-Control Study

Federica Di Spirito et al.

Summary: This case-control study investigated the possible association between ARMD and periodontal disease, but found no significant differences in clinical and radiographic periodontal parameters between ARMD cases and controls. However, among hypertensive ARMD subjects, Clinical Attachment Level values were significantly higher, suggesting a potential link between periodontal disease and ARMD in this subgroup.

DENTISTRY JOURNAL (2021)

Review Immunology

The immunomodulating role of probiotics in the prevention and treatment of oral diseases

Marta Kazmierczyk-Winciorek et al.

Summary: Probiotics, such as Lactobacillus and Bifidobacterium, are beneficial non-pathogenic live microorganisms that can protect the oral cavity from infections like Candida spp. and contribute to improving oral health by modulating immune responses.

CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY (2021)

Review Biochemistry & Molecular Biology

The oralome and its dysbiosis: New insights into oral microbiome-host interactions

Allan Radaic et al.

Summary: The oralome is a summary of the interactions between oral microorganisms and the host, which can impact the health and disease status of the host. Current research focuses on changes in the oral microbiome in the oral environment and discusses techniques for modulating the dysbiotic oral microbiome to prevent and treat diseases.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2021)

Review Dentistry, Oral Surgery & Medicine

Clinical efficacy of probiotics in the treatment of gingivitis: A systematic review and meta-analysis

Z. Akram et al.

AUSTRALIAN DENTAL JOURNAL (2020)

Article Dentistry, Oral Surgery & Medicine

Antibiotic's effectiveness after erupted tooth extractions: A retrospective study

Antonio Barone et al.

ORAL DISEASES (2020)

Review Dentistry, Oral Surgery & Medicine

Do probiotics promote oral health during orthodontic treatment with fixed appliances? A systematic review

Riham Hadj-Hamou et al.

BMC ORAL HEALTH (2020)

Review Microbiology

The Microbiome of Peri-Implantitis: A Systematic Review and Meta-Analysis

Philipp Sahrmann et al.

MICROORGANISMS (2020)

Review Dentistry, Oral Surgery & Medicine

The role of the microbiota in periodontal disease

Mike A. Curtis et al.

PERIODONTOLOGY 2000 (2020)

Review Microbiology

Criteria to Qualify Microorganisms as Probiotic in Foods and Dietary Supplements

Sylvie Binda et al.

FRONTIERS IN MICROBIOLOGY (2020)

Review Physiology

Potential Bidirectional Relationship Between Periodontitis and Alzheimer's Disease

Daniela Liccardo et al.

FRONTIERS IN PHYSIOLOGY (2020)

Review Biotechnology & Applied Microbiology

Role of Probiotics in Oral Health Maintenance Among Patients Undergoing Fixed Orthodontic Therapy: a Systematic Review of Randomized Controlled Clinical Trials

Francesca Katherine Pietri et al.

PROBIOTICS AND ANTIMICROBIAL PROTEINS (2020)

Review Dentistry, Oral Surgery & Medicine

Current understanding of periodontal disease pathogenesis and targets for host-modulation therapy

George Hajishengallis et al.

PERIODONTOLOGY 2000 (2020)

Article Microbiology

The Effect of Lactobacillus salivarius SGL03 on Clinical and Microbiological Parameters in Periodontal Patients

Malgorzata Nedzi-Gora et al.

POLISH JOURNAL OF MICROBIOLOGY (2020)

Review Geriatrics & Gerontology

Utility of Probiotics for Maintenance or Improvement of Health Status in Older People A Scoping Review

Emerald Setbo et al.

JOURNAL OF NUTRITION HEALTH & AGING (2019)

Article Endocrinology & Metabolism

Disentangling What We Know About Microbes and Mental Health

Gregor Reid

FRONTIERS IN ENDOCRINOLOGY (2019)

Review Biochemistry & Molecular Biology

Th17 Cells and the IL-23/IL-17 Axis in the Pathogenesis of Periodontitis and Immune-Mediated Inflammatory Diseases

Kuebra Bunte et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Gastroenterology & Hepatology

Probiotics and prebiotics in intestinal health and disease: from biology to the clinic

Mary Ellen Sanders et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Review Biochemical Research Methods

Shared mechanisms among probiotic taxa: implications for general probiotic claims

Mary Ellen Sanders et al.

CURRENT OPINION IN BIOTECHNOLOGY (2018)

Review Microbiology

Mind-altering with the gut: Modulation of the gut-brain axis with probiotics

Namhee Kim et al.

JOURNAL OF MICROBIOLOGY (2018)

Article Dentistry, Oral Surgery & Medicine

Staging and grading of periodontitis: Framework and proposal of a new classification and case definition

Maurizio S. Tonetti et al.

JOURNAL OF PERIODONTOLOGY (2018)

Review Dentistry, Oral Surgery & Medicine

Systematic review and meta-analysis of double-blind, placebo-controlled, randomized clinical trials using probiotics in chronic periodontitis

Sana Ikram et al.

JOURNAL OF INVESTIGATIVE AND CLINICAL DENTISTRY (2018)

Article Dentistry, Oral Surgery & Medicine

Clinical, Immune, and Microbiome Traits of Gingivitis and Peri-implant Mucositis

G. P. Schincaglia et al.

JOURNAL OF DENTAL RESEARCH (2017)

Article Dentistry, Oral Surgery & Medicine

Clinical effects of probiotics containing Bacillus species on gingivitis: a pilot randomized controlled trial

B. Alkaya et al.

JOURNAL OF PERIODONTAL RESEARCH (2017)

Review Dentistry, Oral Surgery & Medicine

IL-17: overview and role in oral immunity and microbiome

L. Abusleme et al.

ORAL DISEASES (2017)

Article Dentistry, Oral Surgery & Medicine

The Influence of a Bifidobacterium animalis Probiotic on Gingival Health: A Randomized Controlled Clinical Trial

Bahar Eren Kuru et al.

JOURNAL OF PERIODONTOLOGY (2017)

Review Microbiology

The impact of nutrition on intestinal bacterial communities

Harry J. Flint et al.

CURRENT OPINION IN MICROBIOLOGY (2017)

Article Dentistry, Oral Surgery & Medicine

Microbiota at teeth and implants in partially edentulous patients. A 10-year retrospective study

Sigrun Eick et al.

CLINICAL ORAL IMPLANTS RESEARCH (2016)

Article Dentistry, Oral Surgery & Medicine

Effect of the probiotic bacterium Lactobacillus reuteri on white spot lesion development in orthodontic patients

Sotiria Gizani et al.

EUROPEAN JOURNAL OF ORTHODONTICS (2016)

Article Dentistry, Oral Surgery & Medicine

Dental care and dentistry practice in the Medieval Medical School of Salerno

M. Bifulco et al.

BRITISH DENTAL JOURNAL (2016)

Review Infectious Diseases

The role of probiotic bacteria in managing periodontal disease: a systematic review

Victor Haruo Matsubara et al.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2016)

Review Dentistry, Oral Surgery & Medicine

Probiotics for managing caries and periodontitis: Systematic review and meta-analysis

Deborah Gruner et al.

JOURNAL OF DENTISTRY (2016)

Review Immunology

Cytokines IL-17 and IL-22 in the host response to infection

Maria Valeri et al.

PATHOGENS AND DISEASE (2016)

Review Dentistry, Oral Surgery & Medicine

Basic biology and role of interleukin-17 in immunity and inflammation

Camille Zenobia et al.

PERIODONTOLOGY 2000 (2015)

Article Dentistry, Oral Surgery & Medicine

Porcine dermal matrix in the treatment of dehiscence-type defects - an experimental split-mouth animal trial

Stefan Fickl et al.

CLINICAL ORAL IMPLANTS RESEARCH (2015)

Article Dentistry, Oral Surgery & Medicine

Cluster of Bacteria Associated with Peri-Implantitis

G. Rutger Persson et al.

CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH (2014)

Review Environmental Sciences

Microorganisms with Claimed Probiotic Properties: An Overview of Recent Literature

Sabina Fijan

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2014)

Review Dentistry, Oral Surgery & Medicine

Effects of probiotics in periodontal diseases: a systematic review

Nicolas Yanine et al.

CLINICAL ORAL INVESTIGATIONS (2013)

Article Dentistry, Oral Surgery & Medicine

Patient-specific Analysis of Periodontal and Peri-implant Microbiomes

S. M. Dabdoub et al.

JOURNAL OF DENTAL RESEARCH (2013)

Review Immunology

Regulation of intestinal homeostasis and immunity with probiotic lactobacilli

Peter van Baarlen et al.

TRENDS IN IMMUNOLOGY (2013)

Review Pharmacology & Pharmacy

Probiotics and Oral Health

Bernard Bizzini et al.

CURRENT PHARMACEUTICAL DESIGN (2012)

Article Dentistry, Oral Surgery & Medicine

Spontaneous progression of experimental peri-implantitis at implants with different surface characteristics: An experimental study in dogs

Jean-Pierre Albouy et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2012)

Article Immunology

The impact of probiotics and prebiotics on the immune system

Todd R. Klaenhammer et al.

NATURE REVIEWS IMMUNOLOGY (2012)

Article Dentistry, Oral Surgery & Medicine

Anti-infective treatment of peri-implant mucositis: a randomised controlled clinical trial

Lisa J. A. Heitz-Mayfield et al.

CLINICAL ORAL IMPLANTS RESEARCH (2011)

Article Dentistry, Oral Surgery & Medicine

Microbial shift and periodontitis

Alex B. Berezow et al.

PERIODONTOLOGY 2000 (2011)

Article Gastroenterology & Hepatology

The Use of Probiotics in Healthy Volunteers With Evacuation Disorders and Hard Stools A Double-blind, Randomized, Placebo-controlled Study

Mario Del Piano et al.

JOURNAL OF CLINICAL GASTROENTEROLOGY (2010)

Article Dentistry, Oral Surgery & Medicine

The influence of a probiotic milk drink on the development of gingivitis: a pilot study

Benedict Staab et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2009)

Article Genetics & Heredity

Gene expression in periodontal tissues following treatment

Thomas Beikler et al.

BMC MEDICAL GENOMICS (2008)

Article Dentistry, Oral Surgery & Medicine

Replacement therapy for periodontitis: pilot radiographic evaluation in a dog model

Olivia Nackaerts et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2008)

Editorial Material Dentistry, Oral Surgery & Medicine

Innovations in non-surgical periodontal therapy: Consensus Report of the Sixth European Workshop on Periodontology

M. Sanz et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2008)

Article Dentistry, Oral Surgery & Medicine

Guiding periodontal pocket recolonization: a proof of concept

W. Teughels et al.

JOURNAL OF DENTAL RESEARCH (2007)

Article Dentistry, Oral Surgery & Medicine

Anti-inflammatory effects of Lactobacillus brevis (CD2) on periodontal disease

D. N. Della Riccia et al.

ORAL DISEASES (2007)

Article Microbiology

Defining the normal bacterial flora of the oral cavity

JA Aas et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2005)

Review Dentistry, Oral Surgery & Medicine

Herpesviruses in periodontal diseases

J Slots

PERIODONTOLOGY 2000 (2005)

Review Dentistry, Oral Surgery & Medicine

Periodontal microbial ecology

SS Socransky et al.

PERIODONTOLOGY 2000 (2005)

Article Dentistry, Oral Surgery & Medicine

Analytical epidemiology of periodontitis

LN Borrell et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2005)

Article Dentistry, Oral Surgery & Medicine

Use of checkerboard DNA-DNA hybridization to study complex microbial ecosystems

SS Socransky et al.

ORAL MICROBIOLOGY AND IMMUNOLOGY (2004)

Article Microbiology

The collagenase activity of Porphyromonas gingivalis is due to Arg-gingipain

MA Houle et al.

FEMS MICROBIOLOGY LETTERS (2003)

Review Microbiology

Communication among oral bacteria

PE Kolenbrander et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2002)