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CJ Hu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
E Berra et al.
EMBO JOURNAL (2003)
Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1α (HEF-1α) accumulation via redox-dependent mechanisms
VA Shatrov et al.
BLOOD (2003)
Differential regulation of HIF-1α prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells
CL Cioffi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
NO and TNF-α released from activated macrophages stabilize HIF-1α in resting tubular LLC-PK1 cells
J Zhou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1(-/-) mice
M Scortegagna et al.
NATURE GENETICS (2003)
Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803
LA McNeill et al.
BIOCHEMICAL JOURNAL (2002)
Vanadate-induced expression of hypoxia-inducible factor 1α and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species
N Gao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
D Lando et al.
GENES & DEVELOPMENT (2002)
Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1β involves the phosphatidylinositol 3-kinase pathway
DP Stiehl et al.
FEBS LETTERS (2002)
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
D Lando et al.
SCIENCE (2002)
Regulation of vascular endothelial growth factor expression by advanced glycation end products
C Treins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Hypoxia-inducible factor 2α binds to cobalt in vitro
Y Yuan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon et al.
GENES & DEVELOPMENT (2001)
A non-hypoxic, ROS-sensitive pathway mediates TNF-α-dependent regulation of HIF-1α
JJ Haddad et al.
FEBS LETTERS (2001)
MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1α in rasV12 upregulation of VEGF
A Sodhi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells role of the p22phox-containing NADPH oxidase
A Görlach et al.
CIRCULATION RESEARCH (2001)
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
MP Wautier et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2001)
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia -: A mechanism of O2 sensing
NS Chandel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The missing link: A single unifying mechanism for diabetic complications
T Nishikawa et al.
KIDNEY INTERNATIONAL (2000)
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