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Quercetin provides protection against the peripheral nerve damage caused by vincristine in rats by suppressing caspase 3, NF-κB, ATF-6 pathways and activating Nrf2, Akt pathways
Ahmet Yardim et al.
NEUROTOXICOLOGY (2020)
Exploiting Citrus aurantium seeds and their secondary metabolites in the management of Alzheimer disease
Doha H. Abou Baker et al.
TOXICOLOGY REPORTS (2020)
Nano-hesperetin enhances the functional recovery and endogenous remyelination of the optic pathway in focal demyelination model
Saeideh Baradaran et al.
BRAIN RESEARCH BULLETIN (2020)
Hesperidin alleviates chronic restraint stress and lipopolysaccharide-induced Hippocampus and Frontal cortex damage in mice: Role of TLR4/NF-κB, p38 MAPK/JNK, Nrf2/ARE signaling
Mohit Kwatra et al.
NEUROCHEMISTRY INTERNATIONAL (2020)
Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection?
Yusuf A. Haggag et al.
MEDICAL HYPOTHESES (2020)
Transcription factor NRF2 as a promising therapeutic target for Alzheimer's disease
Zhuo Qu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2020)
The antidepressant effects of hesperidin on chronic unpredictable mild stress-induced mice
Huiling Fu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2019)
Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model
Muhammad Ikram et al.
MOLECULAR NEUROBIOLOGY (2019)
Quercetin and Related Chromenone Derivatives as Monoamine Oxidase Inhibitors: Targeting Neurological and Mental Disorders
Priyanka Dhiman et al.
MOLECULES (2019)
Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence
Marziyeh Hajialyani et al.
MOLECULES (2019)
Neuroactive Steroids and GABAergic Involvement in the Neuroendocrine Dysfunction Associated With Major Depressive Disorder and Postpartum Depression
Jamie Maguire
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling
Tahir Muhammad et al.
NUTRIENTS (2019)
Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease
Elizabeta Zaplatic et al.
LIFE SCIENCES (2019)
Cortico-hippocampal memory enhancing activity of hesperetin on scopolamine-induced amnesia in mice: role of antioxidant defense system, cholinergic neurotransmission and expression of BDNF
Ismail O. Ishola et al.
METABOLIC BRAIN DISEASE (2019)
Monoaminergic System Modulation in Depression and Alzheimer's Disease: A New Standpoint?
Maria Grazia Morgese et al.
FRONTIERS IN PHARMACOLOGY (2019)
Hesperetin inhibits neuroinflammation on microglia by suppressing inflammatory cytokines and MAPK pathways
Sun Hyo Jo et al.
ARCHIVES OF PHARMACAL RESEARCH (2019)
Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats
Yongsheng Li et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2019)
The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health
Yala Stevens et al.
NUTRIENTS (2019)
Effect of Hyperhomocysteinemia on Clinical Outcome and Hemorrhagic Transformation After Thrombolysis in Ischemic Stroke Patients
Yun Luo et al.
FRONTIERS IN NEUROLOGY (2019)
Management of oxidative stress and other pathologies in Alzheimer's disease
Miriama Simunkova et al.
ARCHIVES OF TOXICOLOGY (2019)
The endotoxin hypothesis of neurodegeneration
Guy C. Brown
JOURNAL OF NEUROINFLAMMATION (2019)
The Nrf2/HO-1 Axis as Targets for Flavanones: Neuroprotection by Pinocembrin, Naringenin, and Eriodictyol
Solomon Habtemariam
Oxidative Medicine and Cellular Longevity (2019)
Prebiotic UG1601 mitigates constipation-related events in association with gut microbiota: A randomized placebo-controlled intervention study
Jae Ryang Chu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2019)
Dietary Quercetin and Kaempferol: Bioavailability and Potential Cardiovascular-Related Bioactivity in Humans
Wijdan M. Dabeek et al.
NUTRIENTS (2019)
Phytochemicals and cognitive health: Are flavonoids doing the trick?
Ioannis Bakoyiannis et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Monoaminergic system and depression
L. Perez-Caballero et al.
CELL AND TISSUE RESEARCH (2019)
The microbiome in systemic autoimmune disease: mechanistic insights from recent studies
Carina Dehner et al.
CURRENT OPINION IN RHEUMATOLOGY (2019)
The gut microbiome and pharmacology: a prescription for therapeutic targeting of the gut-brain axis
Pauline M. B. Leprun et al.
CURRENT OPINION IN PHARMACOLOGY (2019)
Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression
Cunyou Gao et al.
MEDICAL SCIENCE MONITOR (2019)
A Natural Phenolic Compound Quercetin Showed the Usefulness by Targeting Inflammatory, Oxidative Stress Markers and Augment 5-HT Levels in One of the Animal Models of Depression in Mice
Khadeeja Khan et al.
DRUG RESEARCH (2019)
Hesperidin attenuates learning and memory deficits in APP/PS1 mice through activation of Akt/Nrf2 signaling and inhibition of RAGE/NF-kappa B signaling
Yan Hong et al.
ARCHIVES OF PHARMACAL RESEARCH (2018)
Safety Aspects of the Use of Quercetin as a Dietary Supplement
Susanne Andres et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2018)
Neuroprotective effect of hesperetin and nano-hesperetin on recognition memory impairment and the elevated oxygen stress in rat model of Alzheimer's disease
Elham Kheradmand et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Quercetin attenuates mitochondrial dysfunction and biogenesis via upregulated AMPK/SIRT1 signaling pathway in OA rats
Linan Qiu et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction
Yahel Segal et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2018)
Hesperidin attenuates iron-induced oxidative damage and dopamine depletion in Drosophila melanogaster model of Parkinson's disease
Marcia Rosula Poetini et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2018)
Isoquercetin attenuates oxidative stress and neuronal apoptosis after ischemia/reperfusion injury via Nrf2-mediated inhibition of the NOX4/ROS/NF-κB pathway
Yunyi Dai et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2018)
The Role of LRRK2 in Neurodegeneration of Parkinson Disease
Qin Rui et al.
CURRENT NEUROPHARMACOLOGY (2018)
Hesperidin Methylchalcone Suppresses Experimental Gout Arthritis in Mice by Inhibiting NF-kappa B Activation
Kenji W. Ruiz-Miyazawa et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)
Beneficial Effects of Flavonoids Against Parkinson's Disease
Un Ju Jung et al.
JOURNAL OF MEDICINAL FOOD (2018)
Hesperetin reduces myelin damage and ameliorates glial activation in lysolecithin-induced focal demyelination model of rat optic chiasm
Saeideh Baradaran et al.
LIFE SCIENCES (2018)
Attenuation of Aluminum Chloride-Induced Neuroinflammation and Caspase Activation Through the AKT/GSK-3 beta Pathway by Hesperidin in Wistar Rats
Arokiasamy Justin-Thenmozhi et al.
NEUROTOXICITY RESEARCH (2018)
Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
Farida Larit et al.
PHYTOMEDICINE (2018)
Adverse Reactions to Vaccination From Anaphylaxis to Autoimmunity
Laurel J. Gershwin
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE (2018)
Quercetin attenuates AZT-induced neuroinflammation in the CNS
Yi Yang et al.
SCIENTIFIC REPORTS (2018)
Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States
Deborah S. Hasin et al.
JAMA PSYCHIATRY (2018)
Quercetin in Food: Possible Mechanisms of Its Effect on Memory
Fatemeh Babaei et al.
JOURNAL OF FOOD SCIENCE (2018)
Inflammasome signalling in brain function and neurodegenerative disease
Michael T. Heneka et al.
NATURE REVIEWS NEUROSCIENCE (2018)
Focus on the gut-brain axis: multiple sclerosis, the intestinal barrier and the microbiome
Carlos R. Camara-Lemarroy et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
Bioactive phenolic fraction of Citrus maxima abate lipopolysaccharide-induced sickness behaviour and anorexia in mice: In-silico molecular docking and dynamic studies of biomarkers against NF-κB
Rudrappa Nandeesh et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Hesperidin attenuates depression-related symptoms in mice with mild traumatic brain injury
Morteza Kosari-Nasab et al.
LIFE SCIENCES (2018)
Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain
Amjad Khan et al.
FRONTIERS IN PHARMACOLOGY (2018)
Neuroprotective Effect of Quercetin Nanocrystal in a 6-Hydroxydopamine Model of Parkinson Disease: Biochemical and Behavioral Evidence
Fatemeh Ghaffafi et al.
BASIC AND CLINICAL NEUROSCIENCE (2018)
Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice
Jegan Sakthivel Nadar et al.
NEUROLOGY RESEARCH INTERNATIONAL (2018)
Quercetin Protects Against Stress-Induced Anxiety- and Depression-Like Behavior and Improves Memory in Male Mice
N. Samad et al.
PHYSIOLOGICAL RESEARCH (2018)
Health-promoting effects of the citrus flavanone hesperidin
Chaoyun Li et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2017)
Protective Role of Quercetin in Cadmium-Induced Cholinergic Dysfunctions in Rat Brain by Modulating Mitochondrial Integrity and MAP Kinase Signaling
Richa Gupta et al.
MOLECULAR NEUROBIOLOGY (2017)
BACE1 inhibition could block CSF tau increase
Hemi Malkki
NATURE REVIEWS NEUROLOGY (2017)
Hesperidin ameliorates cognitive dysfunction, oxidative stress and apoptosis against aluminium chloride induced rat model of Alzheimer's disease
Arokiasamy Justin Thenmozhi et al.
NUTRITIONAL NEUROSCIENCE (2017)
Hesperidin, a citrus flavonoid, protects against L-methionine-induced hyperhomocysteinemia by abrogation of oxidative stress, endothelial dysfunction and neurotoxicity in Wistar rats
B. Hemanth Kumar et al.
PHARMACEUTICAL BIOLOGY (2017)
Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats
Kalist Shagirtha et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2017)
Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways
Entaz Bahar et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Glutamate, T cells and multiple sclerosis
Mia Levite
JOURNAL OF NEURAL TRANSMISSION (2017)
Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease
Muhammet Ay et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Aluminium in brain tissue in familial Alzheimer's disease
Ambreen Mirza et al.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2017)
The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. How strong is the evidence and what could be the mechanisms involved?
Gerwyn Morris et al.
METABOLIC BRAIN DISEASE (2017)
Dietary patterns and depression risk: A meta-analysis
Ye Li et al.
PSYCHIATRY RESEARCH (2017)
Quercetin ameliorates learning and memory via the Nrf2-ARE signaling pathway in D-galactose-induced neurotoxicity in mice
Fuxing Dong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Flavonoids: promising natural compounds against viral infections
Hovakim Zakaryan et al.
ARCHIVES OF VIROLOGY (2017)
Citrus consumption and incident dementia in elderly Japanese: the Ohsaki Cohort 2006 Study
Shu Zhang et al.
BRITISH JOURNAL OF NUTRITION (2017)
Gut Microbiota, Nitric Oxide, and Microglia as Prerequisites for Neurodegenerative Disorders
Joyce K. Y. Tse
ACS CHEMICAL NEUROSCIENCE (2017)
Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation
Mahban Rahimifard et al.
AGEING RESEARCH REVIEWS (2017)
Antidepressant-like effects of quercetin in diabetic rats are independent of hypothalamic-pituitary-adrenal axis
Enver Ahmet Demir et al.
ACTA NEUROPSYCHIATRICA (2016)
Role of RAGE in Alzheimer's Disease
Zhiyou Cai et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)
Brain Protection and Cognitive Function: Cocoa Flavonoids as Nutraceuticals
Davide Grassi et al.
CURRENT PHARMACEUTICAL DESIGN (2016)
Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males
Mudi H. Alharbi et al.
EUROPEAN JOURNAL OF NUTRITION (2016)
Antidepressant-like effects of quercetin in diabetic rats are independent of hypothalamic-pituitary-adrenal axis
Enver Ahmet Demir et al.
ACTA NEUROPSYCHIATRICA (2016)
Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions
Natarajan Suganthy et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
Multifaceted effects of aluminium in neurodegenerative diseases: A review
S. Maya et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
ERK-dependent brain-derived neurotrophic factor regulation by hesperidin in mice exposed to chronic mild stress
Cheng-Fu Li et al.
BRAIN RESEARCH BULLETIN (2016)
The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow: an acute, randomised, placebo-controlled cross-over trial in healthy, young adults
Daniel J. Lamport et al.
BRITISH JOURNAL OF NUTRITION (2016)
Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals
Marco Malavolta et al.
CURRENT DRUG TARGETS (2016)
PASS assisted prediction and pharmacological evaluation of hesperidin against scopolamine induced amnesia in mice
Ahmad Farid Habibyar et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Hesperidin Alleviates Lipopolysaccharide-Induced Neuroinflammation in Mice by Promoting the miRNA-132 Pathway
Min Li et al.
INFLAMMATION (2016)
Inhibition of Human Monoamine Oxidase: Biological and Molecular Modeling Studies on Selected Natural Flavonoids
Simone Carradori et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2016)
Neuroprotective effects of ginseng protein on PI3K/Akt signaling pathway in the hippocampus of D-galactose/AlCl3 inducing rats model of Alzheimer's disease
Hongyan Li et al.
JOURNAL OF ETHNOPHARMACOLOGY (2016)
Recent Knowledge on Medicinal Plants as Source of Cholinesterase Inhibitors for the Treatment of Dementia
Rosa Tundis et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2016)
QUERCETIN ATTENUATES NEURONAL DEATH AGAINST ALUMINUM-INDUCED NEURODEGENERATION IN THE RAT HIPPOCAMPUS
D. R. Sharma et al.
NEUROSCIENCE (2016)
Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More
Lucio G. Costa et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Quercetin suppresses NLRP3 inflammasome activation and attenuates histopathology in a rat model of spinal cord injury
W. Jiang et al.
SPINAL CORD (2016)
SUR1 Receptor Interaction with Hesperidin and Linarin Predicts Possible Mechanisms of Action of Valeriana officinalis in Parkinson
Gesivaldo Santos et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Neuroprotective effect of quercetin against oxidative damage and neuronal apoptosis caused by cadmium in hippocampus
Mehmet Kanter et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2016)
Antioxidative Properties and Effect of Quercetin and Its Glycosylated Form (Rutin) on Acetylcholinesterase and Butyrylcholinesterase Activities
Ayokunle O. Ademosun et al.
JOURNAL OF EVIDENCE-BASED INTEGRATIVE MEDICINE (2016)
Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk, randomized, double-blind, placebo-controlled trial in healthy older adults
Rebecca J. Kean et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2015)
On vaccine's adjuvants and autoimmunity: Current evidence and future perspectives
Paolo Pellegrino et al.
AUTOIMMUNITY REVIEWS (2015)
Hesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice
Chaoyun Li et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Hesperidin and Silibinin Ameliorate Aluminum-Induced Neurotoxicity: Modulation of Antioxidants and Inflammatory Cytokines Level in Mice Hippocampus
Ashok Jangra et al.
BIOLOGICAL TRACE ELEMENT RESEARCH (2015)
Role of Environmental Contaminants in the Etiology of Alzheimer's Disease: A Review
Manivannan Yegambaram et al.
CURRENT ALZHEIMER RESEARCH (2015)
Evidence for the Involvement of Potassium Channel Inhibition in the Antidepressant-Like Effects of Hesperidin in the Tail Suspension Test in Mice
Franciele Donato et al.
JOURNAL OF MEDICINAL FOOD (2015)
Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice
Hayate Javed et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2015)
Hesperidin ameliorates heavy metal induced toxicity mediated by oxidative stress in brain of Wistar rats
Mohammad Haaris Ajmal Khan et al.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2015)
In vitro colonic catabolism of orange juice (poly)phenols
Gema Pereira-Caro et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2015)
Identification of the Chemical Constituents in Aqueous Extract of Zhi-Qiao and Evaluation of Its Antidepressant Effect
Ming Wu et al.
MOLECULES (2015)
The role of quercetin on the survival of neuron-like PC12 cells and the expression of α-synuclein
Tae-Beom Ahn et al.
NEURAL REGENERATION RESEARCH (2015)
Quercetin reduces eIF2α phosphorylation by GADD34 induction
Miki Hayakawa et al.
NEUROBIOLOGY OF AGING (2015)
Neuroprotective Effect of Hesperidin on Aluminium Chloride Induced Alzheimer's Disease in Wistar Rats
Arokiasamy Justin Thenmozhi et al.
NEUROCHEMICAL RESEARCH (2015)
The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice
Angelica Maria Sabogal-Guaqueta et al.
NEUROPHARMACOLOGY (2015)
Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats
Chia Ying Chang et al.
NEUROTOXICOLOGY (2015)
Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways
Iandra Holzmann et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2015)
Phytochemical constituents as future antidepressants: a comprehensive review
Roodabeh Bahramsoltani et al.
REVIEWS IN THE NEUROSCIENCES (2015)
Effects of Dietary Components on Cancer of the Digestive System
Sara Zanini et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2015)
Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models
Hamideh Parhiz et al.
PHYTOTHERAPY RESEARCH (2015)
Hesperidin protects brain and sciatic nerve tissues against cisplatin-induced oxidative, histological and electromyographical side effects in rats
Suat Kamisli et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2015)
Role of quercetin in cadmium-induced oxidative stress, neuronal damage, and apoptosis in rats
Cuneyt Unsal et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2015)
Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer's Disease
Filipa I. Baptista et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Hesperidin Alleviates Cognitive Impairment, Mitochondrial Dysfunction and Oxidative Stress in a Mouse Model of Alzheimer's Disease
Dongmei Wang et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2014)
Dietary patterns and the risk of depression in adults: a systematic review of observational studies
Corinna Rahe et al.
EUROPEAN JOURNAL OF NUTRITION (2014)
Retinal neuroprotective effects of quercetin in streptozotocin-induced diabetic rats
Binit Kumar et al.
EXPERIMENTAL EYE RESEARCH (2014)
What is the risk of aluminium as a neurotoxin?
Christopher Exley
EXPERT REVIEW OF NEUROTHERAPEUTICS (2014)
Oxidant and Antioxidant Status in Children With Subacute Sclerosing Panencephalitis
Huseyin Caksen et al.
JOURNAL OF CHILD NEUROLOGY (2014)
Amyloid-beta (Aβ1-42)-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways
Charlotte Regitz et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2014)
Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin - A mini-review
Ali Roohbakhsh et al.
LIFE SCIENCES (2014)
Effects of Long-Term Treatment with Quercetin on Cognition and Mitochondrial Function in a Mouse Model of Alzheimer's Disease
Dong-Mei Wang et al.
NEUROCHEMICAL RESEARCH (2014)
Chronic Functional Bowel Syndrome Enhances Gut-Brain Axis Dysfunction, Neuroinflammation, Cognitive Impairment, and Vulnerability to Dementia
Mak Adam Daulatzai
NEUROCHEMICAL RESEARCH (2014)
Protective effect of hesperidin in a model of Parkinson's disease induced by 6-hydroxydopamine in aged mice
Michelle S. Antunes et al.
NUTRITION (2014)
Quercetin protects the impairment of memory and anxiogenic-like behavior in rats exposed to cadmium: Possible involvement of the acetylcholinesterase and Na+,K+-ATPase activities
Fatima H. Abdalla et al.
PHYSIOLOGY & BEHAVIOR (2014)
Hesperidin restores experimentally induced neurotoxicity in Wistar rats
Mehar Naseem et al.
TOXICOLOGY MECHANISMS AND METHODS (2014)
Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes
Mohammad Ashafaq et al.
BIOMED RESEARCH INTERNATIONAL (2014)
The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs
Yan Li et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)
Natural polyphenols in the management of major depression
Lokesh Pathak et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2013)
Ascorbate Prevents Cell Death From Prolonged Exposure to Glutamate in an In Vitro Model of Human Dopaminergic Neurons
Santiago Ballaz et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2013)
Quercetin protects against the Aβ25-35-induced amnesic injury: Involvement of inactivation of RAGE-mediated pathway and conservation of the NVU
Rui Liu et al.
NEUROPHARMACOLOGY (2013)
QUERCETIN SUPPRESS MICROGLIAL NEUROINFLAMMATORY RESPONSE AND INDUCE ANTIDEPRESSENT-LIKE EFFECT IN OLFACTORY BULBECTOMIZED RATS
P. Rinwa et al.
NEUROSCIENCE (2013)
Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone-Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease
Kuppusamy Tamilselvam et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Neuroprotective Role of Nanoencapsulated Quercetin in Combating Ischemia-Reperfusion Induced Neuronal Damage in Young and Aged Rats
Aparajita Ghosh et al.
PLOS ONE (2013)
Astrocyte signaling and neurodegeneration New insights into CNS disorders
Liliana Brambilla et al.
PRION (2013)
Evidence for the involvement of the serotonergic 5-HT-1A receptors in the antidepressant-like effect caused by hesperidin in mice
Leandro C. Souza et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2013)
Mechanisms of Oxidative Damage in Multiple Sclerosis and Neurodegenerative Diseases: Therapeutic Modulation via Fumaric Acid Esters
De-Hyung Lee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Effects of natural antioxidants in neurodegenerative disease
Sonia Luz Albarracin et al.
NUTRITIONAL NEUROSCIENCE (2012)
Chronic Intraperitoneal and Oral Treatments with Hesperidin Induce Central Nervous System Effects in Mice
Cristina Wasowski et al.
PHYTOTHERAPY RESEARCH (2012)
Quercetin and Sesamin Protect Dopaminergic Cells from MPP+-Induced Neuroinflammation in a Microglial (N9)-Neuronal (PC12) Coculture System
Julie Bournival et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish
S. K. Richetti et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence
Fani L. Neto et al.
Current Neuropharmacology (2011)
Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders
Giovanni Scapagnini et al.
MOLECULAR NEUROBIOLOGY (2011)
Quercetin Protects Against Oxidative Stress Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and Reperfusion
Ajmal Ahmad et al.
NEUROCHEMICAL RESEARCH (2011)
Neuroprotective effect of bioflavonoid quercetin in 6-hydroxydopamine-induced oxidative stress biomarkers in the rat striatum
Nagaraja Haleagrahara et al.
NEUROSCIENCE LETTERS (2011)
Hepatoprotection of quercetin against oxidative stress by induction of metallothionein expression through activating MAPK and PI3K pathways and enhancing Nrf2 DNA-binding activity
Chia-Jui Weng et al.
NEW BIOTECHNOLOGY (2011)
Effect of quercetin and glucuronide metabolites on the monoamine oxidase-A reaction in mouse brain mitochondria
Saki Yoshino et al.
NUTRITION (2011)
Antidepressant effect and pharmacological evaluation of standardized extract of flavonoids from Byrsonima crassifolia
M. Herrera-Ruiz et al.
PHYTOMEDICINE (2011)
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors
Franco Chimenti et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Apoptosis by dietary agents for prevention and treatment of prostate cancer
Naghma Khan et al.
ENDOCRINE-RELATED CANCER (2010)
Anti-ageing and rejuvenating effects of quercetin
Niki Chondrogianni et al.
EXPERIMENTAL GERONTOLOGY (2010)
After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult
Florencia Arredondo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Stimulus-specific regulation of CD63 and CD203c membrane expression in human basophils by the flavonoid quercetin
S. Chirumbolo et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2010)
Suppressive effect of quercetin on acute stress-induced hypothalamic-pituitary-adrenal axis response in Wistar rats
Kyuichi Kawabata et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2010)
Inhibition of nitric oxide production by quercetin in endotoxin/cytokine-stimulated microglia
Tsung-Kuei Kao et al.
LIFE SCIENCES (2010)
Nutraceutical Antioxidants as Novel Neuroprotective Agents
Natalie A. Kelsey et al.
MOLECULES (2010)
Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice
Yan Hou et al.
NEUROPHARMACOLOGY (2010)
Hesperidin pre-treatment attenuates NO-mediated cerebral ischemic reperfusion injury and memory dysfunction
Vaibhav Gaur et al.
PHARMACOLOGICAL REPORTS (2010)
Effect of dietary quercetin on brain quercetin levels and the expression of antioxidant and Alzheimer's disease relevant genes in mice
Patricia Huebbe et al.
PHARMACOLOGICAL RESEARCH (2010)
Reversal by quercetin of corticotrophin releasing factor induced anxiety- and depression-like effect in mice
Pravinkumar Bhutada et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2010)
Protective Effects of Resveratrol and Quercetin Against MPP+ -Induced Oxidative Stress Act by Modulating Markers of Apoptotic Death in Dopaminergic Neurons
Julie Bournival et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2009)
Stimulation of Neurogenesis and Synaptogenesis by Bilobalide and Quercetin via Common Final Pathway in Hippocampal Neurons
Flaubert Tchantchou et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Dietary phenolics: chemistry, bioavailability and effects on health
Alan Crozier et al.
NATURAL PRODUCT REPORTS (2009)
Oxidative stress in developmental brain disorders
Masaharu Hayashi
NEUROPATHOLOGY (2009)
Pharmacological Exploration of the Sedative Mechanism of Hesperidin Identified as the Active Principle of Citrus sinensis Flowers
Silvia Laura Guzman-Gutierrez et al.
PLANTA MEDICA (2009)
Plant polyphenols as dietary antioxidants in human health and disease
Kanti Bhooshan Pandey et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2009)
Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1/2 levels in mice
M. Cecilia Martinez et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2009)
Glial metabolism of quercetin reduces its neurotoxic potential
Katerina Vafeiadou et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: Implications for Parkinson's disease and protection by polyphenols
David Vauzour et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)
Quercetin pharmacokinetics in humans
Young J. Moon et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2008)
Antidepressant-like effect of onion (Allium cepa L.) powder in a rat behavioral model of depression
Hiroyuki Sakakibara et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2008)
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines
Leonardo M. Loscalzo et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Central CRH system in depression and anxiety -: Evidence from clinical studies with CRH1 receptor antagonists
Florian Holsboer et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Health effects of quercetin: From antioxidant to nutraceutical
Agnes W. Boots et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation
Genevieve Bureau et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans
Sarah Egert et al.
JOURNAL OF NUTRITION (2008)
Quercetin, kaempferol and biapigenin from Hypericum perforatum are neuroprotective against excitotoxic insults
Bruno Silva et al.
NEUROTOXICITY RESEARCH (2008)
A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcino genic properties
M. Harwood et al.
FOOD AND CHEMICAL TOXICOLOGY (2007)
Acetylcholinesterase inhibition by flavonoids from agrimonia pilosa
Mankil Jung et al.
MOLECULES (2007)
Flavonoid composition of citrus juices
Giuseppe Gattuso et al.
MOLECULES (2007)
Effects of St. John's Wort extract and single constituents on stress-induced hyperthermia in mice
Oliver Grundmann et al.
PLANTA MEDICA (2006)
Quercetin reverses D-galactose induced neurotoxicity in mouse brain
Jun Lu et al.
BEHAVIOURAL BRAIN RESEARCH (2006)
Antioxidant and neuroprotective effects of hesperidin and its aglycone hesperetin
Jungsook Cho
ARCHIVES OF PHARMACAL RESEARCH (2006)
The HPA and immune axes in stress: the involvement of the serotonergic system
BE Leonard
EUROPEAN PSYCHIATRY (2005)
Synergistic interaction between hesperidin, a natural flavonoid, and diazepam
SP Fernández et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2005)
Polyphenols and prevention of cardiovascular diseases
C Manach et al.
CURRENT OPINION IN LIPIDOLOGY (2005)
Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABAρ1 receptor
JD Goutman et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis
S Fernández et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2004)
Intestinal lymphocyte populations in children with regressive autism: Evidence for extensive mucosal immunopathology
P Ashwood et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2003)
6-Methylapigenin and hesperidin:: new valeriana flavonoids with activity on the CNS
M Marder et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2003)
Interaction between flavonoids and the blood-brain barrier:: in vitro studies
KA Youdim et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Flavonoid modulation of ionic currents mediated by GABAA and GABAC receptors
JD Goutman et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice
C Manach et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2003)
Flavonoid intake and risk of chronic diseases
P Knekt et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2002)
Review article: the concept of entero-colonic encephalopathy, autism and opioid receptor ligands
AJ Wakefield et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2002)
Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
I Erlund et al.
JOURNAL OF NUTRITION (2001)
Allium sativum potentiates suicide gene therapy for murine transitional cell carcinoma
PG Moon et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2000)