4.7 Review

The unexpected versatility of ALP/Enigma family proteins

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

PDLIM2: Signaling pathways and functions in cancer suppression and host immunity

Zong Sheng Guo et al.

Summary: PDZ and LIM domain-containing proteins, such as PDLIM2, play crucial roles in cytoskeleton organization, cell polarization, and differentiation. PDLIM2 regulates the stability and activity of transcription factors, affecting inflammation, immunity, and cancer. It acts as a tumor suppressor in various tissues but can also promote cancer cell proliferation and metastasis in certain types of cancers.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)

Article Agriculture, Dairy & Animal Science

PDLIM5 Affects Chicken Skeletal Muscle Satellite Cell Proliferation and Differentiation via the p38-MAPK Pathway

Haorong He et al.

Summary: This study demonstrated that PDLIM5 can promote proliferation and differentiation of chicken skeletal muscle satellite cells through the p38-MAPK pathway. These findings suggest that PDLIM5 may play a role in the growth and development of chicken skeletal muscle.

ANIMALS (2021)

Article Biology

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation

Pankaj Pathak et al.

Summary: This research demonstrates that the LDB3 protein regulates mechanical stress signaling through interactions with filamin C, HSPA8, and PKC alpha. Mutations in LDB3 lead to early aggregation of filamin C and its chaperones at the muscle Z-disc, ultimately causing protein aggregation myopathy.

COMMUNICATIONS BIOLOGY (2021)

Review Cell Biology

PDLIM1: Structure, function and implication in cancer

Jian-Kang Zhou et al.

Summary: PDLIM1, a cytoskeletal protein belonging to the PDZ-LIM family, acts as a platform for forming protein complexes involved in regulating cytoskeleton and synapse formation. Recent studies reveal dysregulation of PDLIM1 in various tumors, highlighting its crucial roles in tumor initiation and progression.

CELL STRESS (2021)

Article Biochemistry & Molecular Biology

Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities

Joan Teyra et al.

PROTEIN SCIENCE (2020)

Article Medicine, General & Internal

Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation

Oliver Bundgaard Vad et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Genetics & Heredity

Mutations in PDLIM5 are rare in dilated cardiomyopathy but are emerging as potential disease modifiers

Job A. J. Verdonschot et al.

MOLECULAR GENETICS & GENOMIC MEDICINE (2020)

Article Biochemistry & Molecular Biology

Gga-miR-3525 TargetsPDLIM3through the MAPK Signaling Pathway to Regulate the Proliferation and Differentiation of Skeletal Muscle Satellite Cells

Huadong Yin et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biochemistry & Molecular Biology

PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells

Yueli Shi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Cell Biology

Mechanosensing through Direct Binding of Tensed F-Actin by LIM Domains

Xiaoyu Sun et al.

DEVELOPMENTAL CELL (2020)

Article Cell Biology

Novel phospho-switch function of delta-catenin in dendrite development

Ryan Baumert et al.

JOURNAL OF CELL BIOLOGY (2020)

Article Multidisciplinary Sciences

Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism

Jonathan D. Winkelman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Medicine, Research & Experimental

JMJD3 regulates CD4+ T cell trafficking by targeting actin cytoskeleton regulatory gene Pdlim4

Chuntang Fu et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Immunology

NQO1 inhibits the TLR-dependent production of selective cytokines by promoting IκB-(ζ) degradation

Akihiro Kimura et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

Article Biochemistry & Molecular Biology

PDLIM7 and CDH18 regulate the turnover of MDM2 during CDK4/6 inhibitor therapy-induced senescence

Mary E. Klein et al.

ONCOGENE (2018)

Review Biotechnology & Applied Microbiology

Myofibrillar myopathy in the genomic context

Jakub Piotr Fichna et al.

JOURNAL OF APPLIED GENETICS (2018)

Article Cell Biology

Enigma proteins regulate YAP mechanotransduction

Ahmed Elbediwy et al.

JOURNAL OF CELL SCIENCE (2018)

Article Biochemistry & Molecular Biology

Understanding the role of phosphorylation in the binding mechanism of a PDZ domain

Angelo Toto et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2017)

Review Developmental Biology

Mechanical forces during muscle development

Sandra B. Lemke et al.

MECHANISMS OF DEVELOPMENT (2017)

Article Biochemistry & Molecular Biology

PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle

Robert D'Cruz et al.

BIOCHEMICAL JOURNAL (2016)

Article Biochemistry & Molecular Biology

Scaffold protein enigma homolog 1 overcomes the repression of myogenesis activation by inhibitor of DNA binding 2

Miyuki Nakatani et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Cell Biology

PDLIM5 mediates PKC epsilon translocation in PMA-induced growth cone collapse

Bingyu Ren et al.

CELLULAR SIGNALLING (2015)

Article Genetics & Heredity

Use of high-throughput targeted exome-sequencing to screen for copy number variation in hypertrophic cardiomyopathy

L. R. Lopes et al.

EUROPEAN JOURNAL OF MEDICAL GENETICS (2015)

Article Multidisciplinary Sciences

Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5

Yi Yan et al.

NATURE COMMUNICATIONS (2015)

Article Cardiac & Cardiovascular Systems

Cypher and Enigma Homolog Protein Are Essential for Cardiac Development and Embryonic Survival

Yongxin Mu et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2015)

Article Genetics & Heredity

Secondary association of PDLIM5 with paranoid schizophrenia in Emirati patients

Hamdy Moselhy et al.

META GENE (2015)

Review Biochemistry & Molecular Biology

Intrinsically Disordered Proteins and Intrinsically Disordered Protein Regions

Christopher J. Oldfield et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)

Article Medicine, Research & Experimental

Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

Claudia Bang et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Biochemistry & Molecular Biology

A Structural Portrait of the PDZ Domain Family

Andreas Ernst et al.

JOURNAL OF MOLECULAR BIOLOGY (2014)

Article Multidisciplinary Sciences

Enigma Prevents Cbl-c-Mediated Ubiquitination and Degradation of RETMEN2A

Stephen C. Kales et al.

PLOS ONE (2014)

Article Biochemistry & Molecular Biology

HSP70 mediates degradation of the p65 subunit of nuclear factor κB to inhibit inflammatory signaling

Takashi Tanaka et al.

SCIENCE SIGNALING (2014)

Article Biochemistry & Molecular Biology

Cypher/ZASP Is a Novel A-kinase Anchoring Protein

Changsong Lin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Genetics & Heredity

Alp/Enigma Family Proteins Cooperate in Z-Disc Formation and Myofibril Assembly

Anja Katzemich et al.

PLOS GENETICS (2013)

Article Biochemistry & Molecular Biology

Splicing transitions of the anchoring protein ENH during striated muscle development

Jumpei Ito et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Article Cardiac & Cardiovascular Systems

CLP36 Is a Negative Regulator of Glycoprotein VI Signaling in Platelets

Shuchi Gupta et al.

CIRCULATION RESEARCH (2012)

Article Cell Biology

Zasp regulates integrin activation

Mohamed Bouaouina et al.

JOURNAL OF CELL SCIENCE (2012)

Article Neurosciences

Parent-of-origin effects of FAS and PDLIM1 in attention-deficit/hyperactivity disorder

Ke-Sheng Wang et al.

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2012)

Article Biochemistry & Molecular Biology

Robust co-regulation of tyrosine phosphorylation sites on proteins reveals novel protein interactions

Kristen M. Naegle et al.

MOLECULAR BIOSYSTEMS (2012)

Article Biochemistry & Molecular Biology

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

Zhaoxia Qu et al.

CELL AND BIOSCIENCE (2012)

Article Biochemistry & Molecular Biology

Alternative splicing of PDLIM3/ALP, for α-actinin-associated LIM protein 3, is aberrant in persons with myotonic dystrophy

Natsumi Ohsawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Cell Biology

LIM domains regulate protein kinase C activity: A novel molecular function

Andres D. Maturana et al.

CELLULAR SIGNALLING (2011)

Article Biochemistry & Molecular Biology

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

Herbert B. Schiller et al.

EMBO REPORTS (2011)

Article Biochemistry & Molecular Biology

Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy

Hongqiang Cheng et al.

HUMAN MOLECULAR GENETICS (2011)

Article Biochemistry & Molecular Biology

α-Actinin-4 and CLP36 Protein Deficiencies Contribute to Podocyte Defects in Multiple Human Glomerulopathies

Zhongmin Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Urology & Nephrology

Pdlim2 is a novel actin-regulating protein of podocyte foot processes

Laleh Sistani et al.

KIDNEY INTERNATIONAL (2011)

Article Biochemistry & Molecular Biology

PDLIM2 Inhibits T Helper 17 Cell Development and Granulomatous Inflammation Through Degradation of STAT3

Takashi Tanaka et al.

SCIENCE SIGNALING (2011)

Review Biochemistry & Molecular Biology

Nucleocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development

Jennifer Krcmery et al.

BIOESSAYS (2010)

Article Biochemical Research Methods

Interaction prediction and classification of PDZ domains

Sibel Kalyoncu et al.

BMC BIOINFORMATICS (2010)

Article Biotechnology & Applied Microbiology

A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding

Nicolas Lenfant et al.

BMC GENOMICS (2010)

Article Cardiac & Cardiovascular Systems

Splice variants of Enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy

Tomoko Yamazaki et al.

CARDIOVASCULAR RESEARCH (2010)

Review Cell Biology

PDZ domains and their binding partners: structure, specificity, and modification

Ho-Jin Lee et al.

CELL COMMUNICATION AND SIGNALING (2010)

Review Biochemistry & Molecular Biology

Structural Diversity of PDZ-Lipid Interactions

Rodrigo Gallardo et al.

CHEMBIOCHEM (2010)

Article Cardiac & Cardiovascular Systems

Loss of Enigma Homolog Protein Results in Dilated Cardiomyopathy

Hongqiang Cheng et al.

CIRCULATION RESEARCH (2010)

Article Cardiac & Cardiovascular Systems

A ZASP Missense Mutation, S196L, Leads to Cytoskeletal and Electrical Abnormalities in a Mouse Model of Cardiomyopathy

Zhaohui Li et al.

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2010)

Article Endocrinology & Metabolism

Muscle stem cells in developmental and regenerative myogenesis

Jong-Sun Kang et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2010)

Article Oncology

Identification of ZASP, a novel protein associated to Zona occludens-2

Susana Lechuga et al.

EXPERIMENTAL CELL RESEARCH (2010)

Article Cell Biology

Analysis of integrin turnover in fly myotendinous junctions

Lin Yuan et al.

JOURNAL OF CELL SCIENCE (2010)

Article Medicine, Research & Experimental

Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice

Cho-Rok Jung et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Neurosciences

Postsynaptic PDLIM5/Enigma Homolog binds SPAR and causes dendritic spine shrinkage

Scott Herrick et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2010)

Article Biochemistry & Molecular Biology

Coevolution of PDZ domain-ligand interactions analyzed by high-throughput phage display and deep sequencing

Andreas Ernst et al.

MOLECULAR BIOSYSTEMS (2010)

Article Neurosciences

CLP36 interacts with palladin in dorsal root ganglion neurons

Tomohiko Hasegawa et al.

NEUROSCIENCE LETTERS (2010)

Article Biochemistry & Molecular Biology

Molecular determinants of PDLIM2 in suppressing HTLV-I Tax-mediated tumorigenesis

J. Fu et al.

ONCOGENE (2010)

Review Cell Biology

ALP/Enigma PDZ-LIM Domain Proteins in the Heart

Ming Zheng et al.

JOURNAL OF MOLECULAR CELL BIOLOGY (2010)

Review Cell Biology

Extensions of PDZ domains as important structural and functional elements

Conan K. Wang et al.

PROTEIN & CELL (2010)

Article Cell Biology

Localization of Reversion-Induced LIM Protein (RIL) in the Rat Central Nervous System

Yuko Iida et al.

ACTA HISTOCHEMICA ET CYTOCHEMICA (2009)

Article Oncology

PDLIM4, An Actin Binding Protein, Suppresses Prostate Cancer Cell Growth

Donkena Krishna Vanaja et al.

CANCER INVESTIGATION (2009)

Article Cardiac & Cardiovascular Systems

Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy

Takuro Arimura et al.

CARDIOVASCULAR RESEARCH (2009)

Article Biochemistry & Molecular Biology

Characterization of interaction between CLP36 and palladin

Masao Maeda et al.

FEBS JOURNAL (2009)

Article Biochemistry & Molecular Biology

Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death

Ming Zheng et al.

HUMAN MOLECULAR GENETICS (2009)

Article Biochemistry & Molecular Biology

Characterization of CLP36/Elfin/PDLIM1 in the nervous system

Koji Ohno et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

A Class III PDZ Binding Motif in the Myotilin and FATZ Families Binds Enigma Family Proteins: a Common Link for Z-Disc Myopathies

Pernilla von Nandelstadh et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Cell Biology

The initial steps of myofibril assembly: integrins pave the way

John C. Sparrow et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Rapid Evolution of Functional Complexity in a Domain Family

Andreas Ernst et al.

SCIENCE SIGNALING (2009)

Article Cardiac & Cardiovascular Systems

Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel

Andres D. Maturana et al.

CARDIOVASCULAR RESEARCH (2008)

Article Clinical Neurology

Positive association between PDLIM5 and schizophrenia in the Chinese Han population

Chao Li et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

A specificity map for the PDZ domain family

Raffi Tonikian et al.

PLOS BIOLOGY (2008)

Article Cell Biology

Zasp is required for the assembly of functional integrin adhesion sites

Klodiana Jani et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

The LIM domains of WLIM1 define a new class of actin bundling modules

Clement Thomas et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Modeling and analysis of molecular interaction between Smurf1-WW2 domain and various isoforms of LIM mineralization protein

Sreedhara Sangadala et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)

Article Hematology

Plasma membrane Ca2+-ATPase associates with CLP36, α-actinin and actin in human platelets

Larry D. Bozulic et al.

THROMBOSIS AND HAEMOSTASIS (2007)

Article Biochemistry & Molecular Biology

Echocardiographic-determined septal morphology in Z-disc hypertrophic cardiomyopathy

Jeanne L. Theis et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Multidisciplinary Sciences

The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system

A Lasorella et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Gene expression and association analyses of LIM (PDLIM5) in bipolar disorder and schizophrenia

T Kato et al.

MOLECULAR PSYCHIATRY (2005)

Article Cell Biology

Dynamics of Z-band based proteins in developing skeletal muscle cells

J Wang et al.

CELL MOTILITY AND THE CYTOSKELETON (2005)

Article Clinical Neurology

Mutations in ZASP define a novel form of muscular dystrophy in humans

D Selcen et al.

ANNALS OF NEUROLOGY (2005)

Article Biochemistry & Molecular Biology

A Cypher/ZASP mutation associated with dilated cardiomyopathy alters the binding affinity to protein kinase C

T Arimura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Characterization of a new human isoform of the enigma homolog family specifically expressed in skeletal muscle

N Niederländer et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Ophthalmology

Pdlim2, a novel PDZ-LIM domain protein, interacts with α-actinins and filamin A

M Torrado et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)

Review Cell Biology

The LIM domain: From the cytoskeleton to the nucleus

JL Kadrmas et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction

M Vatta et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2003)

Article Neurosciences

A PKCε-ENH-channel complex specifically modulates N-type Ca2+ channels

Y Maeno-Hikichi et al.

NATURE NEUROSCIENCE (2003)

Article Cell Biology

ALP and MLP distribution during myofibrillogenesis in cultured cardiomyocytes

JR Henderson et al.

CELL MOTILITY AND THE CYTOSKELETON (2003)

Article Biochemistry & Molecular Biology

Characterization and in vivo functional analysis of splice variants of cypher

CQ Huang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins

N Frey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL

T Walma et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Actinin-associated LIM protein-deficient mice maintain normal development and structure of skeletal muscle

K Jo et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Article Biochemistry & Molecular Biology

ENH, containing PDZ and LIM domains, heart/skeletal muscle-specific protein, associates with cytoskeletal proteins through the PDZ domain

N Nakagawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)

Article Biochemistry & Molecular Biology

CLP-36 PDZ-LIM protein associates with nonmuscle α-actinin-1 and α-actinin-4

T Vallenius et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)