4.7 Article

miR-23a/b clusters are not essential for the pathogenesis of osteoarthritis in mouse aging and post-traumatic models

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

Long non-coding RNA PCAT-1 regulates apoptosis of chondrocytes in osteoarthritis by sponging miR-27b-3p

Lei Zhou et al.

Summary: PCAT-1 was found to be up-regulated in OA chondrocytes and could promote apoptosis by binding with miR-27b-3p. Therefore, PCAT-1 has potential value as a new therapeutic target for OA patients.

JOURNAL OF BONE AND MINERAL METABOLISM (2021)

Article Multidisciplinary Sciences

Both microRNA-455-5p and-3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis

Yoshiaki Ito et al.

Summary: Osteoarthritis is caused by an imbalance between extracellular matrix synthesis and degradation. Here, the authors show that both strands of microRNA-455, -5p and -3p, target HIF2 alpha and regulate cartilage homeostasis, and show that overexpression of these miRNAs is protective against osteoarthritis in mice.

NATURE COMMUNICATIONS (2021)

Article Orthopedics

MiR-24-3p attenuates IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12

Jin Xu et al.

Summary: The study demonstrated that miR-24-3p expression was decreased in OA cases compared to controls, and IL-1 beta further reduced miR-24-3p expression in chondrocyte cell line CHON-001. Overexpression of miR-24-3p attenuated IL-1 beta-induced chondrocyte injury, as shown by increased cell viability, decreased caspase-3 activity, and reduced levels of pro-inflammatory cytokines (TNF-alpha and IL-18). The protective effects of miR-24-3p were mediated through targeting BCL2L12 in the context of OA therapy.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2021)

Review Biochemistry & Molecular Biology

Exosomal miRNAs in osteoarthritis

Aynaz Mihanfar et al.

MOLECULAR BIOLOGY REPORTS (2020)

Article Multidisciplinary Sciences

Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway

Song Ho Chang et al.

NATURE COMMUNICATIONS (2019)

Article Dentistry, Oral Surgery & Medicine

MicroRNA-23a inhibits osteogenesis of periodontal mesenchymal stem cells by targeting bone morphogenetic protein signaling

Yuchen Zhang et al.

ARCHIVES OF ORAL BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Adipose-derived exosomes deliver miR-23a/b to regulate tumor growth in hepatocellular cancer by targeting the VHL/HIF axis

Yang Liu et al.

JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2019)

Article Multidisciplinary Sciences

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Yingyao Zhou et al.

NATURE COMMUNICATIONS (2019)

Review Cell Biology

Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease

Marcelo A. Mori et al.

CELL METABOLISM (2019)

Article Biochemistry & Molecular Biology

Optimization of Data-Independent Acquisition Mass Spectrometry for Deep and Highly Sensitive Proteomic Analysis

Yusuke Kawashima et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Cardiac & Cardiovascular Systems

Role of endothelial microRNA-23 clusters in angiogenesis in vivo

Satoshi Oikawa et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)

Review Biochemistry & Molecular Biology

Metazoan MicroRNAs

David P. Bartel

Review Rheumatology

Extracellular vesicles in cartilage homeostasis and osteoarthritis

Shigeru Miyaki et al.

CURRENT OPINION IN RHEUMATOLOGY (2018)

Article Pharmacology & Pharmacy

Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes

Hiroyuki Ishitobi et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2018)

Article Biochemistry & Molecular Biology

The microRNA-23a cluster regulates the developmental HoxA cluster function during osteoblast differentiation

Tanner C. Godfrey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Review Medicine, Research & Experimental

The complex landscape of microRNAs in articular cartilage: biology, pathology, and therapeutic targets

Helal Endisha et al.

JCI INSIGHT (2018)

Article Dentistry, Oral Surgery & Medicine

miR-27b-3p Suppressed Osteogenic Differentiation of Maxillary Sinus Membrane Stem Cells by Targeting Sp7

Wei Peng et al.

IMPLANT DENTISTRY (2017)

Article Medicine, Research & Experimental

miR-27 inhibits the NF-κB signaling pathway by targeting leptin in osteoarthritic chondrocytes

Bin Zhou et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)

Article Biochemistry & Molecular Biology

Targeting cellular senescence prevents age-related bone loss in mice

Joshua N. Farr et al.

NATURE MEDICINE (2017)

Article Multidisciplinary Sciences

MicroRNA miR-23a cluster promotes osteocyte differentiation by regulating TGF-β signalling in osteoblasts

Huan-Chang Zeng et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

MicroRNA-23a-3p promotes the development of osteoarthritis by directly targeting SMAD3 in chondrocytes

Liang Kang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Review Orthopedics

Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis

Ronald K. June et al.

JOURNAL OF ORTHOPAEDIC RESEARCH (2016)

Article Multidisciplinary Sciences

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

Darren J. Baker et al.

NATURE (2016)

Article Cell & Tissue Engineering

Mesenchymal Stem Cell-Derived Exosomes Promote Fracture Healing in a Mouse Model

Taisuke Furuta et al.

STEM CELLS TRANSLATIONAL MEDICINE (2016)

Article Physiology

The MicroRNA-23a Has Limited Roles in Bone Formation and Homeostasis In Vivo

J. Park et al.

PHYSIOLOGICAL RESEARCH (2015)

Editorial Material Rheumatology

OSTEOARTHRITIS Is OA a mechanical or systemic disease?

Flavia M. Cicuttini et al.

NATURE REVIEWS RHEUMATOLOGY (2014)

Review Rheumatology

Osteoarthritis: A disease of the joint as an organ

Richard F. Loeser et al.

ARTHRITIS AND RHEUMATISM (2012)

Article Biochemistry & Molecular Biology

Control of Mesenchymal Lineage Progression by MicroRNAs Targeting Skeletal Gene Regulators Trps1 and Runx2

Ying Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

Ying Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Cell Biology

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

Shigeru Miyaki et al.

GENES & DEVELOPMENT (2010)

Article Multidisciplinary Sciences

A network connecting Runx2, SATB2, and the miR-23a∼27a∼24-2 cluster regulates the osteoblast differentiation program

Mohammad Q. Hassan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemistry & Molecular Biology

Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain

H Matsumura et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)