4.7 Article

The Influence of Blonanserin Supersaturation in Liquid and Silica Stabilised Self-Nanoemulsifying Drug Delivery Systems on In Vitro Solubilisation

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Medicine, Research & Experimental

Role of Silica Intrawall Microporosity on Abiraterone Acetate Solubilization and In Vivo Oral Absorption

Ruba Almasri et al.

Summary: SBA-15 mesoporous silica (MPS) is widely used in oral drug delivery, but its application in solidifying lipid-based formulations is still underexplored. This study investigates the impact of MPS microporosity on the solubility and oral pharmacokinetics of the prostate cancer drug abiraterone acetate (AbA) and finds that microporosity plays a key role in enhancing AbA solubilization.

MOLECULAR PHARMACEUTICS (2022)

Article Pharmacology & Pharmacy

The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

Amalie Moller et al.

Summary: This study investigated the influence of lipid formulation classification and physical state on the in vitro solubilisation of blonanserin, a poorly soluble drug. The results showed that liquid SNEDDS was identified as the optimal oral supersaturated lipid-based formulation strategy for BLON.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

Review Chemistry, Multidisciplinary

Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos

Indrani Maji et al.

Summary: The poor aqueous solubility of drug molecules presents challenges in their bioavailability, which solid self-emulsifying drug delivery systems (S-SEDDS) aim to address by solidifying liquid or semi-solid self-emulsifying ingredients onto powders to improve stability, portability, and bioavailability.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Pharmacology & Pharmacy

Enhancement of abiraterone acetate oral bioavailability by supersaturated-silica lipid hybrids

Hayley B. Schultz et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Article Chemistry, Multidisciplinary

Supersaturated-Silica Lipid Hybrids Improve in Vitro Solubilization of Abiraterone Acetate

Hayley B. Schultz et al.

PHARMACEUTICAL RESEARCH (2020)

Article Pharmacology & Pharmacy

Enhancing the oral bioavailability of simvastatin with silica -lipid hybrid particles: The effect of supersaturation and silica geometry

Tahlia R. Meola et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

Review Pharmacology & Pharmacy

Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches - a PEARRL review

Felix Ditzinger et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2019)

Review Pharmacology & Pharmacy

Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges

Paul Joyce et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Pharmacology & Pharmacy

Supersaturated Silica-Lipid Hybrid Oral Drug Delivery Systems: Balancing Drug Loading and In Vivo Performance

Hayley B. Schultz et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2019)

Article Pharmacology & Pharmacy

Supersaturated silica-lipid hybrids (super-SLH): An improved solid-state lipid-based oral drug delivery system with enhanced drug loading

Hayley B. Schultz et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2018)

Article Chemistry, Physical

Engineering intelligent particle-lipid composites that control lipase-mediated digestion

Paul Joyce et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2018)

Article Nanoscience & Nanotechnology

Nanostructured Montmorillonite Clay for Controlling the Lipase-Mediated Digestion of Medium Chain Triglycerides

Tahnee J. Dening et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Review Pharmacology & Pharmacy

50 years of oral lipid-based formulations: Provenance, progress and future perspectives

Orlagh M. Feeney et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Article Pharmacology & Pharmacy

Strategies for formulating and delivering poorly water-soluble drugs

Marta Rodriguez-Aller et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2015)

Article Chemistry, Multidisciplinary

High Solubility Crystalline Pharmaceutical Forms of Blonanserin

D. Maddileti et al.

CRYSTAL GROWTH & DESIGN (2014)

Review Pharmacology & Pharmacy

Lipid-based formulations for oral administration of poorly water-soluble drugs

Huiling Mu et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

Review Pharmacology & Pharmacy

Strategies to Address Low Drug Solubility in Discovery and Development

Hywel D. Williams et al.

PHARMACOLOGICAL REVIEWS (2013)

Review Pharmacology & Pharmacy

New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

Anette Muellertz et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2010)

Article Thermodynamics

Use of thermoanalytical methods in quantification of drug load in mesoporous silicon microparticles

VP Lehto et al.

JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY (2005)

Article Pharmacology & Pharmacy

A dynamic in vitro lipolysis model II:: Evaluation of the model

NH Zangenberg et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2001)