4.6 Article

Dinutuximab beta plus conventional chemotherapy for relapsed/refractory high-risk neuroblastoma: A single-center experience

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Improved Outcome in Children With Newly Diagnosed High-Risk Neuroblastoma Treated With Chemoimmunotherapy: Updated Results of a Phase II Study Using hu14.18K322A

Wayne L. Furman et al.

Summary: Combining hu14.18K322A with chemotherapy improves early response and outcomes in high-risk neuroblastoma. This treatment is well-tolerated and reduces tumor volume in most patients, leading to improved end-of-induction response rates and encouraging 3-year event-free survival.

JOURNAL OF CLINICAL ONCOLOGY (2022)

Article Pediatrics

Early Use of Dinutuximab Beta in Patients with High-Risk Neuroblastoma

Neofit Spasov et al.

Summary: Neuroblastoma is the most common extracranial solid tumor in children, with high-risk neuroblastoma requiring aggressive treatment. Early use of dinutuximab beta post-induction may improve outcomes in patients with high-risk neuroblastoma.

CASE REPORTS IN PEDIATRICS (2021)

Article Oncology

Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) plus Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032

Alice L. Yu et al.

Summary: The study showed that immuotherapy with dinutuximab improved outcomes for high-risk neuroblastoma patients. Although early termination for efficacy resulted in a smaller sample size, clinically significant long-term survival differences were observed.

CLINICAL CANCER RESEARCH (2021)

Article Oncology

Clinical and Pathological Evidence of Anti-GD2 Immunotherapy Induced Differentiation in Relapsed/Refractory High-Risk Neuroblastoma

Jaume Mora et al.

Summary: The anti-tumor activity of anti-GD2 monoclonal antibodies has been demonstrated through immunological cytotoxicity and direct cell death induction. Studies on high-risk neuroblastoma patients treated with anti-GD2 mAbs have shown significant objective responses, with some patients experiencing long periods of stable disease. Comprehensive imaging evaluation of lesions in these patients revealed potential tissue differentiation induced by the antibodies, suggesting a novel mechanism of action.

CANCERS (2021)

Article Pediatrics

Managing Adverse Events Associated with Dinutuximab Beta Treatment in Patients with High-Risk Neuroblastoma: Practical Guidance

Giuseppe Barone et al.

Summary: Neuroblastoma is the most common extracranial solid tumor in children, and high-risk neuroblastoma is challenging to treat with poor prognosis. Immunotherapy with anti-GD2 antibodies, such as dinutuximab beta, has been shown to improve survival rates. However, it is associated with adverse events that may be challenging for clinicians to manage.

PEDIATRIC DRUGS (2021)

Article Oncology

Induction Chemotherapy With an Anti-GD2 Monoclonal Antibody (Dinutuximab) and Cytokines in Children With Newly Diagnosed High-risk Neuroblastoma: A Case Series

Jessica Gartrell et al.

Summary: The combination of chimeric anti-GD2 monoclonal antibody (dinutuximab) and chemotherapy has shown efficacy and tolerability in high-risk neuroblastoma patients, but further studies are needed for validation.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2021)

Article Oncology

Nivolumab and dinutuximab beta in two patients with refractory neuroblastoma

Karoline Ehlert et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

High-dose131I-mIBG as consolidation therapy in pediatric patients with relapsed neuroblastoma and ganglioneuroblastoma: the Japanese experience

Hiroshi Wakabayashi et al.

ANNALS OF NUCLEAR MEDICINE (2020)

Article Oncology

Ifosfamide, carboplatin, and etoposide for neuroblastoma

Brian H. Kushner et al.

CANCER (2013)

Article Medicine, General & Internal

Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma.

Alice L. Yu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Oncology

Topotecan, cyclophosphamide, and etoposide (TCE) in the treatment of high-risk neuroblastoma.: Results of a phase-II trial

Thorsten Simon et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2007)

Article Oncology

Irinotecan plus temozolomide for relapsed or refractory neuroblastoma

Brian H. Kushner et al.

JOURNAL OF CLINICAL ONCOLOGY (2006)