☆ 4.6 Review

Advances in peptides encoded by non-coding RNAs: A cargo in exosome

FRONTIERS IN ONCOLOGY (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Biochemistry & Molecular Biology

Exosomal lncRNA TUG1 from cancer-associated fibroblasts promotes liver cancer cell migration, invasion, and glycolysis by regulating the miR-524-5p/SIX1 axis

Le Lu et al.

Summary: Exosomes derived from cancer-associated fibroblasts (CAFs) promote migration, invasion, and glycolysis in hepatocellular carcinoma (HCC) cells through the miR-524-5p/SIX1 axis. TUG1 and SIX1 are upregulated in HCC patients with metastasis, while miR-524-5p is downregulated.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Upregulation of exosomal circPLK1 promotes the development of non-small cell lung cancer through the miR-1294/ high mobility group protein A1 axis

Chuankui Li et al.

Summary: This study found that circPLK1 expression was upregulated in NSCLC patients and its high expression was associated with a poor prognosis. Exosomes derived from NSCLC serum could enhance the migration, invasion, and replication of NSCLC cells while inhibiting apoptosis. The overexpression of circPLK1 also promoted the malignant phenotype of NSCLC cells. Molecular analyses revealed that circPLK1 directly targeted miR-1294 and negatively regulated its activity, resulting in the progression of NSCLC. The findings suggest a potential therapeutic strategy targeting exosomal circPLK1 in NSCLC treatment.

BIOENGINEERED (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Role of Cardiomyocyte-Derived Exosomal MicroRNA-146a-5p in Macrophage Polarization and Activation

Cong Chen et al.

Summary: The study revealed that cardiomyocyte-derived exosomal miR-146a-5p affected macrophage polarization, promoting M1 macrophage polarization, inhibiting M2 macrophage polarization, and exerting an anti-inflammatory effect by targeting TRAF6.

DISEASE MARKERS (2022)

添加到收藏夹

Article Pharmacology & Pharmacy

Exosome-transmitted circVMP1 facilitates the progression and cisplatin resistance of non-small cell lung cancer by targeting miR-524-5p-METTL3/SOX2 axis

Hongya Xie et al.

Summary: This study reveals the regulatory mechanism of circRNA circVMP1 in NSCLC progression and cisplatin resistance. circVMP1 promotes the malignant behavior and cisplatin resistance of NSCLC through the miR-524-5p-METTL3/SOX2 axis targeting.

DRUG DELIVERY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

A peptide encoded by pri-miRNA-31 represses autoimmunity by promoting Treg differentiation

Hong Zhou et al.

Summary: Recent evidence has shown that miPEP31, a peptide encoded by pri-miRNA-31, plays an important role in promoting the differentiation of T-regs and suppressing autoimmune diseases through mechanisms such as downregulating miR-31 expression. This reveals a potential therapeutic peptide for modulating miRNA expression and treating autoimmune diseases.

EMBO REPORTS (2022)

添加到收藏夹

Article Oncology

Exosomal LncRNA RP5-977B1 as a novel minimally invasive biomarker for diagnosis and prognosis in non-small cell lung cancer

Ling Min et al.

Summary: Based on the study, the expression level of exosomal LncRNA RP5-977B1 was found to be higher in NSCLC compared to the healthy controls. The exosomal RP5-977B1 showed better diagnostic capability than conventional biomarkers in testing and multicentric validation cohort, and its high expression was closely related to worse prognosis in NSCLC.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2022)

添加到收藏夹

Article Nanoscience & Nanotechnology

Exosomal lncRNA HOTAIR Promotes the Progression and Angiogenesis of Endometriosis via the miR-761/HDAC1 Axis and Activation of STAT3-Mediated Inflammation

Lu Zhang et al.

Summary: Exosomal HOTAIR promotes the progression and angiogenesis of endometriosis by regulating the miR-761/HDAC1 axis and activating STAT3-mediated inflammation, both in vitro and in vivo, providing a potential treatment for endometriosis.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2022)

添加到收藏夹

Article Immunology

miR-203, fine-tunning neuroinflammation by juggling different components of NE-κB signaling

Shufang Li et al.

Summary: miR-203 plays a role in promoting inflammation and neurodisruption by targeting Akirin2 and 14-3-3 theta. It may act as a master modulator fine-tuning neuroinflammation by juggling different components of the NF-kappa B signaling pathway.

JOURNAL OF NEUROINFLAMMATION (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating the Wnt/beta-catenin pathway

Yaming Li et al.

Summary: The protein-coding ability of circRNAs in TNBC has not been well understood. This study identified a circRNA called circ-EIF6, which was associated with poorer prognosis and clinicopathological characteristics in TNBC patients. Functional experiments showed that circ-EIF6 promoted proliferation and metastasis of TNBC cells, mediated by encoding a novel peptide called EIF6-224aa that interacted with MYH9, leading to activation of the Wnt/β-catenin pathway.

MOLECULAR THERAPY (2022)

添加到收藏夹

Review Medicine, Research & Experimental

Roles and clinical application of exosomal circRNAs in the diagnosis and treatment of malignant tumors

Dong Ye et al.

Summary: Exosomal circRNAs are nucleic acid molecules found in microvesicles secreted by cells, playing important roles in intercellular communication and gene expression regulation. They can modulate tumor growth and metastasis in tumors and can be used as biomarkers for tumor diagnosis and treatment.

JOURNAL OF TRANSLATIONAL MEDICINE (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation

Chuanchao Zhang et al.

Summary: This study identifies a human long noncoding RNA (lncRNA)-derived micropeptide, PACMP, which functions to maintain CtIP abundance and promote poly(ADP-ribosyl)ation. Targeting PACMP inhibits tumor growth through synthetic lethal interaction between CtIP and PARP inhibitions, and enhances sensitivity to various anticancer drugs and radiation.

MOLECULAR CELL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis

Abhishek Tyagi et al.

Summary: Smoking is associated with increased risk of lung cancer brain metastasis. Chronic nicotine exposure recruits specific cells, secretes specific genes, and enhances the metastatic capacity of tumor cells in the brain.

ONCOGENE (2022)

添加到收藏夹

Article Cell Biology

circFAM120B functions as a tumor suppressor in esophageal squamous cell carcinoma via the miR-661/PPM1L axis and the PKR/p38 MAPK/EMT pathway

Huan Song et al.

Summary: Extensive changes in circRNA expression contribute to cancer hallmarks. In this study, circFAM120B was found to be downregulated in esophageal squamous cell carcinoma (ESCC) and its expression level was associated with patient survival. CircFAM120B acts as a tumor suppressor by sponging miR-661 to restore the expression of PPM1L, and by promoting ubiquitination-dependent degradation of RNA-dependent protein kinase (PKR) to regulate the p38 MAPK signaling pathway and suppress epithelial-mesenchymal transitions (EMTs) in ESCC cells.

CELL DEATH & DISEASE (2022)

添加到收藏夹

Article Cell Biology

Serum-derived extracellular vesicles facilitate temozolomide resistance in glioblastoma through a HOTAIR-dependent mechanism

Xiaosong Wang et al.

Summary: In this study, the researchers found that extracellular vesicles (EVs) transfer a long non-coding RNA (lncRNA) called HOTAIR, which regulates resistance to the chemotherapy drug temozolomide (TMZ) in glioblastoma (GBM). Through in vitro and in vivo experiments, it was demonstrated that HOTAIR promotes tumor growth, increases invasiveness, and enhances resistance to TMZ. In GBM cells, HOTAIR competitively binds to miR-526b-3p, weakening its ability to bind to EVA1 and consequently increasing EVA1 expression. Furthermore, HOTAIR carried by serum-EVs suppresses miR-526b-3p-mediated inhibition of EVA1, promoting tumor growth and TMZ resistance in vivo.

CELL DEATH & DISEASE (2022)

添加到收藏夹

Article Oncology

Exosomal circDNER enhances paclitaxel resistance and tumorigenicity of lung cancer via targeting miR-139-5p/ITGB8

Jinyou Li et al.

Summary: In this study, the researchers found that circDNER could suppress the progression of lung cancer by regulating the miR-139-5p/ITGB8 axis, suggesting that circDNER may serve as a potential prognostic biomarker and therapeutic target for lung cancer treatment.

THORACIC CANCER (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Noncoding RNAs in the Glycolysis of Ovarian Cancer

Chunmei Zhang et al.

Summary: Energy metabolism reprogramming is a characteristic feature of tumors, and non-coding RNAs play an important role in regulating glycolysis. This review summarizes the regulatory mechanisms and explores potential therapeutic targets.

FRONTIERS IN PHARMACOLOGY (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Bone mesenchymal stem cells (BMSCs)-derived exosomal microRNA-21-5p regulates Kruppel-like factor 3 (KLF3) to promote osteoblast proliferation in vitro

Murong You et al.

Summary: The study found that BMSCs-derived exosomes can enhance proliferation, osteoblastic differentiation, and ALP activity of hFOB1.19 cells through the regulation of miR-21-5p, providing a potential therapeutic strategy for osteoporosis.

BIOENGINEERED (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Colorectal cancer stem cell-derived exosomal long intergenic noncoding RNA 01315 (LINC01315) promotes proliferation, migration, and stemness of colorectal cancer cells

Youran Li et al.

Summary: This research investigates the role of LINC01315 in colorectal cancer stem cells and whether it exists in colorectal cancer stem cell-derived exosomes. The results show that exosomal LINC01315 derived from colorectal cancer stem cells promotes the proliferation, migration, and stemness of colorectal cancer cells.

BIOENGINEERED (2022)

添加到收藏夹

Article Oncology

Oncopeptide MBOP Encoded by LINC01234 Promotes Colorectal Cancer through MAPK Signaling Pathway

Chunyuan Tang et al.

Summary: This study reports the identification and characterization of a peptide called MEK1-binding oncopeptide (MBOP) encoded by LINC01234, which is highly expressed in colorectal cancer (CRC) and plays an oncogenic role in tumorigenesis. MBOP interacts with MEK1 and activates the MEK1/pERK/MMP2/MMP9 signaling pathway. The degradation of MBOP is mediated by the E3 ubiquitin-protein transferases MAEA and RMND5A. These findings suggest that MBOP could serve as a potential target and prognostic indicator for clinical therapy of CRC.

CANCERS (2022)

添加到收藏夹

Review Oncology

Circular RNAs and Their Role in Exosomes

Zeping Han et al.

Summary: This review summarizes the biological functions of circRNAs and exosomes, and explores the potential roles of exosomal circRNAs in different diseases.

FRONTIERS IN ONCOLOGY (2022)

添加到收藏夹

Article Oncology

Exosome-transmitted miR-769-5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53

Xinming Jing et al.

Summary: In this study, it was found that cisplatin-resistant gastric cancer (GC) cells communicate with the tumor microenvironment by secreting microvesicles. The upregulation of miR-769-5p in GC tissues and its enrichment in exosomes from cisplatin-resistant patients' serum were observed. The biologically active miR-769-5p could be integrated into exosomes and delivered to sensitive cells, spreading cisplatin resistance. The underlying mechanism involved miR-769-5p targeting CASP9 and promoting the degradation of p53 through the ubiquitin-proteasome pathway.

CLINICAL AND TRANSLATIONAL MEDICINE (2022)

添加到收藏夹

Article Oncology

Loss of exosomal miR-26a-5p contributes to endometrial cancer lymphangiogenesis and lymphatic metastasis

Jing Wang et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2022)

添加到收藏夹

Article Medicine, Research & Experimental

Exosome-mediated lncRNA SND1-IT1 from gastric cancer cells enhances malignant transformation of gastric mucosa cells via up-regulating SNAIL1

Guohua Jin et al.

Summary: Exosome-mediated lncRNA SND1-IT1 from GC cells enhances malignant transformation of GES-1 cells via up-regulating SNAIL1.

JOURNAL OF TRANSLATIONAL MEDICINE (2022)

添加到收藏夹

Article Pathology

Exosomal MiR-423-3p inhibits macrophage M2 polarization to suppress the malignant progression of cervical cancer

Xin Yan et al.

Summary: This study found that exosomal miR-423-3p inhibited macrophage M2 polarization to suppress the progression of cervical cancer cells.

PATHOLOGY RESEARCH AND PRACTICE (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Downregulation of lncRNA APCDD1L-AS1 due to DNA hypermethylation and loss of VHL protein expression promotes the progression of clear cell renal cell carcinoma

Wuping Yang et al.

Summary: APCDD1L-AS1 inhibits the progression of ccRCC and its reduced expression could be caused by DNA hypermethylation and loss of VHL protein expression. Therefore, APCDD1L-AS1 may serve as a new therapeutic target in the treatment of ccRCC.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Exosomal circRNA FNDC3B promotes the progression of esophageal squamous cell carcinoma by sponging miR-490-5p and regulating thioredoxin reductase 1 expression

Bo Tang et al.

Summary: Exosomal circFNDC3B drives the progression of esophageal squamous cell carcinoma (ESCC) by regulating the miR-490-5p/TXNRD1 axis, suggesting circFNDC3B as a potential therapeutic target.

BIOENGINEERED (2022)

添加到收藏夹

Article Toxicology

Exosomal miR-455-3p from BMMSCs prevents cardiac ischemia-reperfusion injury

Yue Wang et al.

Summary: This study reveals that miR-455-3p secreted by BMMSCs targets the MEKK1-MKK4-JNK signaling pathway through exosomes, providing protection against myocardial ischemia-reperfusion damage.

HUMAN & EXPERIMENTAL TOXICOLOGY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Smartly responsive DNA-miRNA hybrids packaged in exosomes for synergistic enhancement of cancer cell apoptosis

Fan Zhang et al.

Summary: A miRNA self-responsive drug delivery system was proposed to achieve synergistic inhibition of breast cancer cells by intelligently linking endogenous and exogenous miRNAs.

NANOSCALE (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

CircRAPGEF5 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma through the miR-1236-3p/ZEB1 Axis and Serves as a Potential Biomarker

Huixin Zhou et al.

Summary: circRAPGEF5 is overexpressed in lung adenocarcinoma and promotes the proliferation and metastasis of lung adenocarcinoma through the miR-1236-3p/ZEB1 axis. Exosomal circRAPGEF5 may serve as a potential biomarker for lung adenocarcinoma.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2022)

添加到收藏夹

Article Oncology

Translation of noncoding RNAs and cancer

Bo Zhou et al.

Summary: This article summarizes the importance of noncoding RNAs (ncRNAs) and their encoded peptides/proteins in cancer research, introduces the methods, tools, and databases for identifying and validating these peptides/proteins, and discusses the future application prospects and challenges.

CANCER LETTERS (2021)

添加到收藏夹

Article Oncology

Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC

Yiwen Huang et al.

Summary: The study found that colorectal cancer cell-derived exosomal lncRNA SNHG10 inhibits the function of NK cells by upregulating INHBC expression, ultimately promoting tumor growth.

CANCER CELL INTERNATIONAL (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Review Oncology

Non-coding RNAs related to angiogenesis in gynecological cancer

Neda Rahimian et al.

Summary: Gynecological cancer is influenced by non-coding RNAs, particularly microRNAs, which regulate angiogenesis. Understanding the molecular mechanisms of microRNAs in regulating angiogenesis may offer new treatment options for gynecological cancer.

GYNECOLOGIC ONCOLOGY (2021)

添加到收藏夹

Review Biotechnology & Applied Microbiology

An overview on miRNA-encoded peptides in plant biology research

Ankita Yadav et al.

Summary: This review discusses the importance of miPEPs as regulators of miRNAs, which enhance the activity of miRNAs by increasing their accumulation and subsequently downregulating target genes to improve plant growth and plant-microbe interaction. miPEPs are considered novel and effective tools for enhancing desired plant traits.

GENOMICS (2021)

添加到收藏夹

Article Cell Biology

LncRNA-encoded microproteins: A new form of cargo in cell culture-derived and circulating extracellular vesicles

Tanxi Cai et al.

Summary: Advancements in omics-based technologies have revealed the abundant presence of microproteins in extracellular vesicles (EVs) derived from glioma cancer cells, suggesting a novel mechanism for intercellular communication. Circulating microproteins are primarily enriched in EVs in human plasma, with preliminary data indicating potential diagnostic applications in identifying glioma patients based on divergent expression profiles of EV microproteins compared to healthy donors.

JOURNAL OF EXTRACELLULAR VESICLES (2021)

添加到收藏夹

Article Medicine, Research & Experimental

Micropeptide ASAP encoded by LINC00467 promotes colorectal cancer progression by directly modulating ATP synthase activity

Qiwei Ge et al.

Summary: The study identified a 94 amino acid-length micropeptide encoded by lncRNA LINC00467 in colorectal cancer, named ASAP, that promoted colorectal cancer cell proliferation by interacting with mitochondria and ATP synthase activity. High expression of ASAP and LINC00467 predicted poor prognosis in colorectal cancer patients.

JOURNAL OF CLINICAL INVESTIGATION (2021)

添加到收藏夹

Article Oncology

Hsa_circ_0065149 is an Indicator for Early Gastric Cancer Screening and Prognosis Prediction

Yongfu Shao et al.

PATHOLOGY & ONCOLOGY RESEARCH (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Micropeptide CIP2A-BP encoded by LINC00665 inhibits triple-negative breast cancer progression

Binbin Guo et al.

EMBO JOURNAL (2020)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

The LINC00961 transcript and its encoded micropeptide, small regulatory polypeptide of amino acid response, regulate endothelial cell function

Helen L. Spencer et al.

CARDIOVASCULAR RESEARCH (2020)

添加到收藏夹

Article Immunology

LncRNA-encoded polypeptide ASRPS inhibits triple-negative breast cancer angiogenesis

Yirong Wang et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2020)

添加到收藏夹

Review Cell Biology

Biogenesis and Functions of Circular RNAs Come into Focus

Mei-Sheng Xiao et al.

TRENDS IN CELL BIOLOGY (2020)

添加到收藏夹

Article Oncology

Exosome-transmitted circular RNA hsa_circ_0051443 suppresses hepatocellular carcinoma progression

Wei Chen et al.

CANCER LETTERS (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

Peptide SMIM30 promotes HCC development by inducing SRC/YES1 membrane anchoring and MAPK pathway activation

Yanan Pang et al.

JOURNAL OF HEPATOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

Song Zhu et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Small Protein Hidden in lncRNA LOC90024 Promotes Cancerous RNA Splicing and Tumorigenesis

Nan Meng et al.

ADVANCED SCIENCE (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

The diversity, plasticity, and adaptability of cap-dependent translation initiation and the associated machinery

Katherine L. B. Borden et al.

RNA BIOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Identification of miPEP133 as a novel tumor-suppressor microprotein encoded by miR-34a pri-miRNA

Min Kang et al.

MOLECULAR CANCER (2020)

添加到收藏夹

Article Genetics & Heredity

Exosomal Circ-MEMO1 Promotes the Progression and Aerobic Glycolysis of Non-small Cell Lung Cancer Through Targeting MiR-101-3p/KRAS Axis

Chengzhi Ding et al.

FRONTIERS IN GENETICS (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

ZFAS1 Exerts an Oncogenic Role via Suppressing miR-647 in an m6A-Dependent Manner in Cervical Cancer

Zhijuan Yang et al.

ONCOTARGETS AND THERAPY (2020)

添加到收藏夹

Article Biotechnology & Applied Microbiology

CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes

Wanying Wu et al.

GENOME BIOLOGY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling

Xiao Zheng et al.

MOLECULAR CANCER (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma

Liang Yang et al.

MOLECULAR CANCER (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1

Xin Xia et al.

MOLECULAR CANCER (2019)

添加到收藏夹

Article Genetics & Heredity

CircCode: A Powerful Tool for Identifying circRNA Coding Ability

Peisen Sun et al.

FRONTIERS IN GENETICS (2019)

添加到收藏夹

Article Biochemical Research Methods

Characterization and identification of long non-coding RNAs based on feature relationship

Guangyu Wang et al.

BIOINFORMATICS (2019)

添加到收藏夹

Article Oncology

Serum miR-100 is a potential biomarker for detection and outcome prediction of glioblastoma patients

Huiping Zhang et al.

CANCER BIOMARKERS (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Exosome-Mediated Transfer of lncRNA HOTTIP Promotes Cisplatin Resistance in Gastric Cancer Cells by Regulating HMGAI/miR-218 Axis

Jingyu Wang et al.

ONCOTARGETS AND THERAPY (2019)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Translation of the circular RNA circ-catenin promotes liver cancer cell growth through activation of the Wnt pathway

Wei-Cheng Liang et al.

GENOME BIOLOGY (2019)

添加到收藏夹

Article Oncology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

Yibing Yang et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

添加到收藏夹

Article Oncology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

Yibing Yang et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

An epi(c)genetic war: Pathogens, cancer and human genome

Deepa Rajagopalan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2018)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

A comprehensive evaluation of the genetic architecture of sudden cardiac arrest

Foram N. Ashar et al.

EUROPEAN HEART JOURNAL (2018)

添加到收藏夹

Letter Biochemistry & Molecular Biology

IRESfinder: Identifying RNA internal ribosome entry site in eukaryotic cell using framed k-mer features

Jian Zhao et al.

JOURNAL OF GENETICS AND GENOMICS (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

Maolei Zhang et al.

ONCOGENE (2018)

添加到收藏夹

Review Pharmacology & Pharmacy

Circular RNA and its mechanisms in disease: From the bench to the clinic

Bing Han et al.

PHARMACOLOGY & THERAPEUTICS (2018)

添加到收藏夹

Article Oncology

Elevated circulating miR-182 acts as a diagnostic biomarker for early colorectal cancer

Xiangxiang Liu et al.

CANCER MANAGEMENT AND RESEARCH (2018)

添加到收藏夹

Article Multidisciplinary Sciences

A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma

Maolei Zhang et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹

Article Medicine, Research & Experimental

circGprc5a Promoted Bladder Oncogenesis and Metastasis through Gprc5a-Targeting Peptide

Chaohui Gu et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

The emerging role of lncRNAs in inflammatory bowel disease

Reza Yarani et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2018)

添加到收藏夹

Article Biochemistry & Molecular Biology

A Peptide Encoded by a Putative lncRNA HOXB-AS3 Suppresses Colon Cancer Growth

Jin-Zhou Huang et al.

MOLECULAR CELL (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Bayesian prediction of RNA translation from ribosome profiling

Brandon Malone et al.

NUCLEIC ACIDS RESEARCH (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

CPC2: a fast and accurate coding potential calculator based on sequence intrinsic features

Yu-Jian Kang et al.

NUCLEIC ACIDS RESEARCH (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

Qiupeng Zheng et al.

NATURE COMMUNICATIONS (2016)

添加到收藏夹

Article Multidisciplinary Sciences

circRNADb: A comprehensive database for human circular RNAs with protein-coding annotations

Xiaoping Chen et al.

SCIENTIFIC REPORTS (2016)

添加到收藏夹

Letter Cell Biology

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

Yan Li et al.

CELL RESEARCH (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation

Alexander P. Fields et al.

MOLECULAR CELL (2015)

添加到收藏夹

Article Multidisciplinary Sciences

Primary transcripts of microRNAs encode regulatory peptidesPrimary transcripts of microRNAs encode regulatory peptides

Dominique Lauressergues et al.

NATURE (2015)

添加到收藏夹

Article Oncology

Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p

Guoping Ding et al.

ONCOTARGET (2015)

添加到收藏夹

Article Oncology

Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer

Qier Li et al.

TUMOR BIOLOGY (2015)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Extensive identification and analysis of conserved small ORFs in animals

Sebastian D. Mackowiak et al.

GENOME BIOLOGY (2015)

添加到收藏夹

Article Biochemical Research Methods

PLEK: a tool for predicting long non-coding RNAs and messenger RNAs based on an improved k-mer scheme

Aimin Li et al.

BMC BIOINFORMATICS (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation

Ariel A. Bazzini et al.

EMBO JOURNAL (2014)

添加到收藏夹

Article Biochemistry & Molecular Biology

A Human Short Open Reading Frame ( sORF)-encoded Polypeptide That Stimulates DNA End Joining

Sarah A. Slavoff et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Quantitative profiling of peptides from RNAs classified as noncoding

Sudhakaran Prabakaran et al.

NATURE COMMUNICATIONS (2014)

添加到收藏夹

Review Cell Biology

Extracellular vesicles: Exosomes, microvesicles, and friends

Graca Raposo et al.

JOURNAL OF CELL BIOLOGY (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Circular RNAs are a large class of animal RNAs with regulatory potency

Sebastian Memczak et al.

NATURE (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

Liguo Wang et al.

NUCLEIC ACIDS RESEARCH (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts

Liang Sun et al.

NUCLEIC ACIDS RESEARCH (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Long Noncoding RNAs with snoRNA Ends

Qing-Fei Yin et al.

MOLECULAR CELL (2012)

添加到收藏夹

Article Genetics & Heredity

Polyadenylation-Dependent Control of Long Noncoding RNA Expression by the Poly(A)-Binding Protein Nuclear 1

Yves B. Beaulieu et al.

PLOS GENETICS (2012)

添加到收藏夹

Article Biochemical Research Methods

PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

Michael F. Lin et al.

BIOINFORMATICS (2011)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Non-coding RNAs: could they be the answer?

Fabricio F. Costa

BRIEFINGS IN FUNCTIONAL GENOMICS (2011)

添加到收藏夹

Article Biochemical Research Methods

sORF finder: a program package to identify small open reading frames with high coding potential

Kousuke Hanada et al.

BIOINFORMATICS (2010)

添加到收藏夹

Article Biochemistry & Molecular Biology

IRESite-a tool for the examination of viral and cellular internal ribosome entry sites

Martin Mokrejs et al.

NUCLEIC ACIDS RESEARCH (2010)

添加到收藏夹

Review Biochemistry & Molecular Biology

Origin, Biogenesis, and Activity of Plant MicroRNAs

Olivier Voinnet

CELL (2009)

添加到收藏夹

Article Multidisciplinary Sciences

Serum MicroRNAs Are Promising Novel Biomarkers

Shlomit Gilad et al.

PLOS ONE (2008)

添加到收藏夹

Article Biochemistry & Molecular Biology

Transcriptional noise and the fidelity of initiation by RNA polymerase II

Kevin Struhl

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

添加到收藏夹

Article Immunology

Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function

CR Liu et al.

JOURNAL OF IMMUNOLOGY (2006)

添加到收藏夹

Article Biochemistry & Molecular Biology

IRESite: the database of experimentally verified IRES structures (www.iresite.org)

Martin Mokrejs et al.

NUCLEIC ACIDS RESEARCH (2006)

添加到收藏夹

Article Hematology

Preparation of human ovarian cancer ascites-derived exosomes for a clinical trial

H Navabi et al.

BLOOD CELLS MOLECULES AND DISEASES (2005)

添加到收藏夹

Article Multidisciplinary Sciences

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

Y Okazaki et al.

NATURE (2002)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.