4.6 Article

Cervical squamous cell carcinoma of unknown primary: Oncological outcomes and prognostic factors

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Otorhinolaryngology

Transoral robotic surgery (TORS) using the da Vinci Xi: prospective analysis of feasibility, safety, and outcomes

Jeroen Meulemans et al.

Summary: This study evaluated the safety and effectiveness of Xi-TORS in the treatment of head and neck cancer, showing a high success rate, good survival rates, and improved quality of life.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2022)

Review Oncology

Systematic review of the CUP trials characteristics and perspectives for next-generation studies

Elie Rassy et al.

Summary: The paper summarizes and evaluates therapeutic research for unknown primary cancer (CUP) over the past five years. Based on this evaluation, recommendations for clinical trial designs are made to improve the impact of CUP research on patients.

CANCER TREATMENT REVIEWS (2022)

Review Otorhinolaryngology

Prognostic Significance of Extranodal Extension in HPV-Mediated Oropharyngeal Carcinoma: A Systematic Review and Meta-analysis

Liliya Benchetrit et al.

Summary: Extranodal extension (ENE) in patients with HPV+ oropharyngeal squamous cell carcinoma (OPSCC) is moderately associated with increased risk of overall mortality and distant recurrence. These findings can inform exclusion criteria for treatment trials and aid in refined risk stratification.

OTOLARYNGOLOGY-HEAD AND NECK SURGERY (2021)

Article Oncology

Prognostic value of clinical and radiologic extranodal extension and their role in the 8th edition TNM cN classification for HPV-negative oropharyngeal carcinoma

Avinash Pilar et al.

Summary: The study evaluated the performance of TNM-8 versus TNM-7 classification for HPV-negative oropharyngeal cancer, focusing on the prognostic contribution of radiologic extranodal extension (rENE). Results showed that both cENE and rENE are prognostic factors, with the cENE+/rENE+ subset having the worst outcome. A refined cN-category incorporating both cENE and rENE parameters outperformed TNM-8 and TNM-7 in predicting patient outcomes.

ORAL ONCOLOGY (2021)

Article Medicine, General & Internal

Genomic correlates of response and resistance to immune checkpoint inhibitors in carcinomas of unknown primary

Elie Rassy et al.

Summary: Research has shown that patients with CUP who have a higher tumor mutation burden may have a better response to ICI. Compared to other tumors eligible for ICI treatment, CUP has a higher prevalence of genetic mutations affecting ICI tolerance. Further research is needed to validate these findings.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2021)

Article Otorhinolaryngology

Swedish National Multicenter Study on Head and Neck Cancer of Unknown Primary: Prognostic Factors and Impact of Treatment on Survival

Lars Axelsson et al.

Summary: The study found that age, performance status, and N stage were significant prognostic factors for overall survival in HNCUP patients. There was no significant difference in overall 5-year survival between the group treated with neck dissection and (chemo) radiation and the group treated with primary (chemo) radiation.

INTERNATIONAL ARCHIVES OF OTORHINOLARYNGOLOGY (2021)

Review Medicine, Research & Experimental

Narrow band imaging in head and neck unknown primary carcinoma: A systematic review and meta-analysis

Pasquale Di Maio et al.

LARYNGOSCOPE (2020)

Article Oncology

Predictors of survival and recurrence after primary surgery for cervical metastasis of unknown primary

Won Ki Cho et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2020)

Article Medicine, Research & Experimental

HPV status in unknown primary head and neck cancer: Prognosis and treatment outcomes

Shayan Cheraghlou et al.

LARYNGOSCOPE (2019)

Article Otorhinolaryngology

Roles of Ki-67 and p16 as biomarkers for unknown primary head and neck squamous cell carcinoma

Toshiya Maebayashi et al.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY (2019)

Review Otorhinolaryngology

Comprehensive management of HPV-related squamous cell carcinoma of the head and neck of unknown primary

Elie Rassy et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2019)

Review Otorhinolaryngology

Role of palatine tonsillectomy in the diagnostic workup of head and neck squamous cell carcinoma of unknown primary origin: A systematic review and meta-analysis

Pasquale Di Maio et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2019)

Article Otorhinolaryngology

Ultraviolet light-related DNA damage mutation signature distinguishes cutaneous from mucosal or other origin for head and neck squamous cell carcinoma of unknown primary site

Jason W. Chan et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2019)

Article Otorhinolaryngology

Squamous cell carcinoma of unknown primary of the head and neck: Favorable prognostic factors comparable to those in oropharyngeal cancer

Margaret J. Zhou et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2018)

Article Medical Laboratory Technology

Human Papillomavirus Testing in Head and Neck Carcinomas Guideline From the College of American Pathologists

James S. Lewis et al.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE (2018)

Article Multidisciplinary Sciences

Treatment outcomes of unknown primary squamous cell carcinoma of the head and neck

Yu-Hsuan Hung et al.

PLOS ONE (2018)

Review Oncology

Precision medicine based on epigenomics: the paradigm of carcinoma of unknown primary

Sebastian Moran et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2017)

Article Otorhinolaryngology

Transoral Robotic Surgery-Assisted Endoscopy With Primary Site Detection and Treatment in Occult Mucosal Primaries

Kyle M. Hatten et al.

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY (2017)

Article Otorhinolaryngology

Neck dissection for unknown cancer of the head and neck in the era of chemoradiation

Mark J. Amsbaugh et al.

AMERICAN JOURNAL OF OTOLARYNGOLOGY (2017)

Review Oncology

Neck lymph node metastases from unknown primary

Alberto Daniele Arosio et al.

CANCER TREATMENT REVIEWS (2017)

Review Otorhinolaryngology

Narrow band imaging for the diagnosis of head and neck squamous cell carcinoma: A systematic review

Benjamin Cosway et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2016)

Article Otorhinolaryngology

Impact of p16 expression, nodal status, and smoking on oncologic outcomes of patients with head and neck unknown primary squamous cell carcinoma

Peter R. Dixon et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2016)

Article Otorhinolaryngology

Management of neck metastases of unknown primary origin united in two European centers

Jos Straetmans et al.

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY (2015)

Article Otorhinolaryngology

Head and neck squamous cell carcinoma of unknown primary: Neck dissection and radiotherapy or definitive radiotherapy

Candan Demiroz et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2014)

Article Otorhinolaryngology

p16 status, pathologic and clinical characteristics, biomolecular signature, and long-term outcomes in head and neck squamous cell carcinomas of unknown primary

Lanea M. Keller et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2014)

Review Otorhinolaryngology

Contemporary management of lymph node metastases from an unknown primary to the neck: I. A review of diagnostic approaches

Primoz Strojan et al.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2013)

Article Medicine, Research & Experimental

Cancer of unknown primary: Does treatment modality make a difference?

Ashley E. Balaker et al.

LARYNGOSCOPE (2012)

Article Otorhinolaryngology

Head and neck squamous cell carcinoma from an unknown primary site

Audrey Wallace et al.

AMERICAN JOURNAL OF OTOLARYNGOLOGY (2011)