Photocatalytic aerobic oxidative deoximation reaction with degradable rhodamine B

Herein, we report an environment-friendly method for deoximation, i.e. photocatalytic aerobic oxidative deoximation reaction with degradable rhodamine B. In the reaction, visible light was employed as the driving force, while air was used as a green, cheap and safe oxidant. In comparison with reported deoximation reactions driven by light, the photosensitizer, i.e. rhodamine B, was cheap, less toxic and degradable, while the substrate scope of the reaction was very wide. This work may provide a practical protocol for deoximation, which is a significant transformation in the synthetic industry.

Automated summary

Here, we present an environmentally friendly method for deoximation, namely photocatalytic aerobic oxidative deoximation reaction utilizing degradable rhodamine B. In this reaction, visible light was used as the driving force, while air served as a green, cheap and safe oxidant. Compared to previous light-driven deoximation reactions, the photosensitizer, rhodamine B, was cost-effective, less toxic, and degradable, and the reaction exhibited a wide substrate scope. This study may offer a practical protocol for deoximation, which holds significant importance in the synthetic industry.