4.6 Review

Pseudomonas aeruginosa Cytotoxins: Mechanisms of Cytotoxicity and Impact on Inflammatory Responses

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT

Mohamed F. Mohamed et al.

Summary: Pseudomonas aeruginosa secretes ExoT, a toxin that inhibits NLRC4-dependent inflammatory responses during wound infection. The T3SS recognition leads to phosphorylation cascade involving Abl/PKC delta/NLRC4, which activates NLRC4 inflammasome and initiates inflammatory responses to limit P. aeruginosa infection. ExoT functions as the main anti-inflammatory agent by targeting CrkII and blocking the phosphorylation cascade.

NATURE COMMUNICATIONS (2022)

Article Cell Biology

Pseudomonas aeruginosa ExoT induces G1 cell cycle arrest in melanoma cells

Mohamed F. Mohamed et al.

Summary: Research has shown that ExoT induces potent apoptotic cytotoxicity in cancer cell lines through two distinct mechanisms and significantly reduces tumor growth in melanoma. ExoT exhibits antiproliferative function in melanoma cells by causing cell cycle arrest in G1 interphase through dampening G1/S checkpoint proteins. Both domains of ExoT contribute to G1 cell cycle arrest in melanoma, with ADPRT likely involving the Crk adaptor protein.

CELLULAR MICROBIOLOGY (2021)

Article Multidisciplinary Sciences

The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis

Vincent Deruelle et al.

Summary: The phospholipase ExoU from Pseudomonas aeruginosa acts on plasma membrane lipids in infected cells, causing membrane rupture and host cell necrosis. Once injected into the host cytoplasm, ExoU requires a host chaperone found on secretory vesicles to reach the plasma membrane and exert its phospholipase activity.

NATURE COMMUNICATIONS (2021)

Review Cell Biology

Cell death mechanisms in eukaryotes

J. Grace Nirmala et al.

CELL BIOLOGY AND TOXICOLOGY (2020)

Article Medicine, Research & Experimental

Inhibitory effects of JQ1 on listeria monocytogenes-induced acute liver injury by blocking BRD4/RIPK1 axis

Zhao Qian et al.

BIOMEDICINE & PHARMACOTHERAPY (2020)

Editorial Material Multidisciplinary Sciences

Pseudomonas aeruginosa in cystic fibrosis: A chronic cheater

Christopher M. Waters et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

Pseudomonas aeruginosa Induced Host Epithelial Cell Mitochondrial Dysfunction

Nicholas M. Maurice et al.

SCIENTIFIC REPORTS (2019)

Review Biotechnology & Applied Microbiology

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Zheng Pang et al.

BIOTECHNOLOGY ADVANCES (2019)

Article Microbiology

Flagellar Stators Stimulate c-di-GMP Production by Pseudomonas aeruginosa

Amy E. Baker et al.

JOURNAL OF BACTERIOLOGY (2019)

Review Cell Biology

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

Rumani Singh et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)

Article Cell Biology

Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway

Justin S. A. Perry et al.

NATURE CELL BIOLOGY (2019)

Review Immunology

NLRP3 Inflammasome and Inflammatory Bowel Disease

Yu Zhen et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Cardiac & Cardiovascular Systems

Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

Chunxia Yao et al.

CIRCULATION (2018)

Review Immunology

Recent advances in inflammasome biology

David E. Place et al.

CURRENT OPINION IN IMMUNOLOGY (2018)

Article Medicine, Research & Experimental

Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease

Liming Mao et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Immunology

Necroptosis: a regulated inflammatory mode of cell death

Yogesh K. Dhuriya et al.

JOURNAL OF NEUROINFLAMMATION (2018)

Article Biochemistry & Molecular Biology

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

Alessandro Annibaldi et al.

MOLECULAR CELL (2018)

Review Biotechnology & Applied Microbiology

Targeting the NLRP3 inflammasome in inflammatory diseases

Matthew S. J. Mangan et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

Article Food Science & Technology

The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model

Christina Kloth et al.

TOXINS (2018)

Review Immunology

Damage-Associated Molecular Patterns in Inflammatory Diseases

Jong Seong Roh et al.

IMMUNE NETWORK (2018)

Review Immunology

Pseudomonas aeruginosa in Chronic Lung Infections: How to Adapt Within the Host?

Emmanuel Faure et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Cardiac & Cardiovascular Systems

Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases

Dongling Liu et al.

BASIC RESEARCH IN CARDIOLOGY (2018)

Review Immunology

Inflammation: A Double-Edged Sword in the Response to Pseudomonas aeruginosa Infection

Christina K. Lin et al.

JOURNAL OF INNATE IMMUNITY (2017)

Review Biochemistry & Molecular Biology

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

Jianjin Shi et al.

TRENDS IN BIOCHEMICAL SCIENCES (2017)

Article Multidisciplinary Sciences

Pseudomonas aeruginosa Exolysin promotes bacterial growth in lungs, alveolar damage and bacterial dissemination

Stephanie Bouillot et al.

SCIENTIFIC REPORTS (2017)

Review Microbiology

Structure, function and regulation of Pseudomonas aeruginosa porins

Sylvie Chevalier et al.

FEMS MICROBIOLOGY REVIEWS (2017)

Article Biochemistry & Molecular Biology

Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis

Jonathan Maelfait et al.

EMBO JOURNAL (2017)

Review Biochemistry & Molecular Biology

Initiation and execution mechanisms of necroptosis: an overview

Sasker Grootjans et al.

CELL DEATH AND DIFFERENTIATION (2017)

Article Biochemistry & Molecular Biology

Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway

Suruchi N. Schock et al.

CELL DEATH AND DIFFERENTIATION (2017)

Review Immunology

Programmed cell death as a defence against infection

Ine Jorgensen et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Enhanced annotations and features for comparing thousands of Pseudomonas genomes in the Pseudomonas genome database

Geoffrey L. Winsor et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Microbiology

Antibiotic resistance in Pseudomonas aeruginosa and alternative therapeutic options

Maitrayee Chatterjee et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2016)

Review Cell Biology

The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

Deepika Sharma et al.

JOURNAL OF CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

Pore-forming activity and structural autoinhibition of the gasdermin family

Jingjin Ding et al.

NATURE (2016)

Article Multidisciplinary Sciences

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis

Rossana G. Iannitti et al.

NATURE COMMUNICATIONS (2016)

Review Immunology

Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity

Jieling Yang et al.

CURRENT OPINION IN IMMUNOLOGY (2015)

Review Pharmacology & Pharmacy

The increasing threat of Pseudomonas aeruginosa high-risk clones

Antonio Oliver et al.

DRUG RESISTANCE UPDATES (2015)

Article Immunology

Caspase-11 activates a canonical NLRP3 inflammasome by promoting K+ efflux

Sebastian Ruehl et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2015)

Article Immunology

Caspase-4 mediates non-canonical activation of the NLRP3 inflammasome in human myeloid cells

Jonathan L. Schmid-Burgk et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2015)

Review Infectious Diseases

Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: Mechanisms and epidemiology

Anais Potron et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2015)

Review Cell Biology

NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration

Jiangyuan Gao et al.

MEDIATORS OF INFLAMMATION (2015)

Article Multidisciplinary Sciences

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

Jianjin Shi et al.

NATURE (2015)

Review Multidisciplinary Sciences

Necroptosis and its role in inflammation

Manolis Pasparakis et al.

NATURE (2015)

Review Cell Biology

Live to die another way: modes of programmed cell death and the signals emanating from dying cells

Yaron Fuchs et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

Article Cell Biology

Pseudomonas aeruginosa uses T3SS to inhibit diabetic wound healing

Josef Goldufsky et al.

WOUND REPAIR AND REGENERATION (2015)

Article Microbiology

Novel Type III Effectors in Pseudomonas aeruginosa

David Burstein et al.

Article Multidisciplinary Sciences

Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3

Seokwon Kang et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E. Lawlor et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes

Elena Vigano et al.

NATURE COMMUNICATIONS (2015)

Article Cell Biology

Activation of Necroptosis in Multiple Sclerosis

Dimitry Ofengeim et al.

CELL REPORTS (2015)

Review Biotechnology & Applied Microbiology

The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms

Tsiry Rasamiravaka et al.

BIOMED RESEARCH INTERNATIONAL (2015)

Review Biochemistry & Molecular Biology

Old, new and emerging functions of caspases

S. Shalini et al.

CELL DEATH AND DIFFERENTIATION (2015)

Article Microbiology

Genome Sequences of Three Strains of the Pseudomonas aeruginosa PA7 Clade

Amine M. Boukerb et al.

GENOME ANNOUNCEMENTS (2015)

Article Gastroenterology & Hepatology

Necroptosis Is Active in Children With Inflammatory Bowel Disease and Contributes to Heighten Intestinal Inflammation

Maria Pierdomenico et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2014)

Article Physiology

The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung

Trevor C. Stevens et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)

Article Critical Care Medicine

Pseudomonas aeruginosa Type-3 Secretion System Dampens Host Defense by Exploiting the NLRC4-coupled Inflammasome

Emmanuel Faure et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)

Article Medicine, Research & Experimental

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

Kenji Mizumura et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Medicine, Research & Experimental

Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression

Qing Wei et al.

LABORATORY INVESTIGATION (2014)

Article Multidisciplinary Sciences

Inflammatory caspases are innate immune receptors for intracellular LPS

Jianjin Shi et al.

NATURE (2014)

Review Biotechnology & Applied Microbiology

Targeting inflammation in the treatment of type 2 diabetes: time to start

Marc Y. Donath

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Multidisciplinary Sciences

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

Dan Weng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Biochemistry & Molecular Biology

A Plug Release Mechanism for Membrane Permeation by MLKL

Lijing Su et al.

STRUCTURE (2014)

Article Public, Environmental & Occupational Health

Clinical and economic consequences of hospital-acquired resistant and multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis

Dilip Nathwani et al.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2014)

Article Biochemistry & Molecular Biology

PIDD mediates and stabilizes the interaction between RAIDD and Caspase-2 for the PIDDosome assembly

Tae-Ho Jang et al.

BMB REPORTS (2013)

Review Microbiology

Antimicrobial Resistance and Virulence: a Successful or Deleterious Association in the Bacterial World?

Alejandro Beceiro et al.

CLINICAL MICROBIOLOGY REVIEWS (2013)

Article Biochemistry & Molecular Biology

Identification of the Major Ubiquitin-binding Domain of the Pseudomonas aeruginosa ExoU A2 Phospholipase

David M. Anderson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

William J. Kaiser et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Medicine, Research & Experimental

Antiinflammatory effects of apoptotic cells

Peter M. Henson et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Multidisciplinary Sciences

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3

John R. Lukens et al.

NATURE (2013)

Article Multidisciplinary Sciences

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

Bo Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

Jon A. Hagar et al.

SCIENCE (2013)

Article Biochemistry & Molecular Biology

TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation

S. Jouan-Lanhouet et al.

CELL DEATH AND DIFFERENTIATION (2012)

Article Biochemistry & Molecular Biology

Pseudomonas aeruginosa Exotoxin Y Is a Promiscuous Cyclase That Increases Endothelial Tau Phosphorylation and Permeability

Cristhiaan D. Ochoa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Editorial Material Cell Biology

Caspase-2 at a glance

Luca L. Fava et al.

JOURNAL OF CELL SCIENCE (2012)

Article Immunology

Apoptotic cells suppress mast cell inflammatory responses via the CD300a immunoreceptor

Chigusa Nakahashi-Oda et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Review Immunology

Regulation of inflammasome signaling

Vijay A. K. Rathinam et al.

NATURE IMMUNOLOGY (2012)

Review Oncology

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis

Tsukasa Seya et al.

ONCOIMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane

Z. T. Schug et al.

CELL DEATH AND DIFFERENTIATION (2011)

Article Immunology

Full Virulence of Pseudomonas aeruginosa Requires OprF

Laurene Fito-Boncompte et al.

INFECTION AND IMMUNITY (2011)

Article Biochemistry & Molecular Biology

Ubiquitin and ubiquitin-modified proteins activate the Pseudomonas aeruginosa T3SS cytotoxin, ExoU

David M. Anderson et al.

MOLECULAR MICROBIOLOGY (2011)

Article Multidisciplinary Sciences

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Claudia Guenther et al.

NATURE (2011)

Editorial Material Multidisciplinary Sciences

PROGRAMMED CELL DEATH Apoptosis meets necrosis

Marcus E. Peter

NATURE (2011)

Article Multidisciplinary Sciences

Non-canonical inflammasome activation targets caspase-11

Nobuhiko Kayagaki et al.

NATURE (2011)

Article Multidisciplinary Sciences

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway

Sudan He et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biochemistry & Molecular Biology

Pseudomonas aeruginosa: all roads lead to resistance

Elena B. M. Breidenstein et al.

TRENDS IN MICROBIOLOGY (2011)

Article Biochemistry & Molecular Biology

Activation and Specificity of Human Caspase-10

Katherine Wachmann et al.

BIOCHEMISTRY (2010)

Review Biochemistry & Molecular Biology

The Inflammasomes

Kate Schroder et al.

Review Biochemistry & Molecular Biology

Regulation of mitochondrial biogenesis

Francois R. Jornayvaz et al.

ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)

Review Microbiology

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

Michael Hogardt et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2010)

Review Cell Biology

Clearance of apoptotic cells: implications in health and disease

Michael R. Elliott et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Pseudomonas Exotoxin A-Mediated Apoptosis Is Bak Dependent and Preceded by the Degradation of Mcl-1

Xing Du et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Review Food Science & Technology

AB Toxins: A Paradigm Switch from Deadly to Desirable

Oludare Odumosu et al.

TOXINS (2010)

Article Biochemistry & Molecular Biology

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He et al.

Review Microbiology

Role of Pseudomonas aeruginosa type III effectors in disease

Joanne Engel et al.

CURRENT OPINION IN MICROBIOLOGY (2009)

Article Microbiology

Effects of bacterial N-acyl homoserine lactones on human Jurkat T lymphocytes-OdDHL induces apoptosis via the mitochondrial pathway

Christoph A. Jacobi et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2009)

Article Biochemical Research Methods

Modeling Pseudomonas aeruginosa pathogenesis in plant hosts

Melissa Starkey et al.

NATURE PROTOCOLS (2009)

Review Microbiology

Pyroptosis: host cell death and inflammation

Tessa Bergsbaken et al.

NATURE REVIEWS MICROBIOLOGY (2009)

Review Microbiology

The type III secretion system of Pseudomonas aeruginosa: infection by injection

Alan R. Hauser

NATURE REVIEWS MICROBIOLOGY (2009)

Article Microbiology

Effects of rhamnolipid-biosurfactant on cell surface of Pseudomonas aeruginosa

A. Sotirova et al.

MICROBIOLOGICAL RESEARCH (2009)

Review Pathology

The inflammatory response to cell death

Kenneth L. Rock et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)

Article Environmental Sciences

Orf1/SpcS chaperones ExoS for type three secretion by Pseudomonas aeruginosa

Da-Kang Shen et al.

BIOMEDICAL AND ENVIRONMENTAL SCIENCES (2008)

Article Biochemistry & Molecular Biology

The nature and character of the transition state for the ADP-ribosyltransferase reaction

Rene Jorgensen et al.

EMBO REPORTS (2008)

Article Immunology

Pseudomonas aeruginosa induces localized immunosuppression during pneumonia

Maureen H. Diaz et al.

INFECTION AND IMMUNITY (2008)

Review Veterinary Sciences

Apoptosis: A review of pro-apoptotic and anti-apoptotic pathways and dysregulation in disease

Mauria A. O'Brien et al.

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE (2008)

Review Biochemistry & Molecular Biology

BH3-only proteins in apoptosis and beyond: an overview

E. Lomonosova et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

Pseudomonas aeruginosa activates caspase 1 through Ipaf

Edward A. Miao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Biochemistry & Molecular Biology

Apoptosis in the development of the immune system

J. T. Opferman

CELL DEATH AND DIFFERENTIATION (2008)

Review Biochemistry & Molecular Biology

Clearance of apoptotic cells by phagocytes

L-P Erwig et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Immunology

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome

Fayyaz S. Sutterwala et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2007)

Article Immunology

Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation

Luigi Franchi et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2007)

Review Microbiology

Type III secretion systems and disease

Bryan Coburn et al.

CLINICAL MICROBIOLOGY REVIEWS (2007)

Article Immunology

The role of flagellin versus motility in acute lung disease caused by Pseudomonas aeruginosa

Viviane Balloy et al.

JOURNAL OF INFECTIOUS DISEASES (2007)

Article Microbiology

Multiple roles of biosurfactants in structural biofilm development by Pseudomonas aeruginosa

Sunje Johanna Pamp et al.

JOURNAL OF BACTERIOLOGY (2007)

Article Biochemistry & Molecular Biology

Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis

Christian Ottmann et al.

EMBO JOURNAL (2007)

Article Medicine, Research & Experimental

The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T-mediated virulence

Priya Balachandran et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Review Pathology

Apoptosis: A review of programmed cell death

Susan Elmore

TOXICOLOGIC PATHOLOGY (2007)

Article Cell Biology

Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation

Anthony W. Maresso et al.

CELLULAR MICROBIOLOGY (2007)

Article Genetics & Heredity

Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis

Amitabha Bandyopadhyay et al.

PLOS GENETICS (2006)

Review Microbiology

The type III secretion injectisome

Guy R. Cornelis

NATURE REVIEWS MICROBIOLOGY (2006)

Article Biotechnology & Applied Microbiology

Monorhamnolipids and 3-(3-hydroxyalkanoyloxy)alkanoic acids (HAAs) production using Escherichia coli as a heterologous host

Natividad Cabrera-Valladares et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2006)

Article Multidisciplinary Sciences

Pseudomonas aeruginosa type III-secreted toxin ExoT inhibits host-cell division by targeting cytokinesis at multiple steps

Sasha H. Shafikhani et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Involvement of Toll-like receptor 5 in the recognition of flagellated bacteria

Vincent Feuillet et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

The discovery of SycO highlights a new function for type III secretion effector chaperones

Michel Letzelter et al.

EMBO JOURNAL (2006)

Review Infectious Diseases

Targeting mechanisms of Pseudomonas aeruginosa pathogenesis

E Kipnis et al.

MEDECINE ET MALADIES INFECTIEUSES (2006)

Article Pharmacology & Pharmacy

Bacterial redox protein azurin induce apoptosis in human osteosarcoma U2OS cells

DS Yang et al.

PHARMACOLOGICAL RESEARCH (2005)

Article Biochemistry & Molecular Biology

Uncoupling Crk signal transduction by Pseudomonas exoenzyme T

Q Deng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Microbiology

Actin cytoskeleton disruption by ExoY and its effects on Pseudomonas aeruginosa invasion

BA Cowell et al.

FEMS MICROBIOLOGY LETTERS (2005)

Article Biochemistry & Molecular Biology

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

A Degterev et al.

NATURE CHEMICAL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Lysophospholipase A activity of Pseudomonas aeruginosa type III secretory toxin ExoU

M Tamura et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Review Cell Biology

Apoptosis and genomic instability

B Zhivotovsky et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

How bacterial ADP-ribosylating toxins recognize substrates

JJ Sun et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)

Review Biochemistry & Molecular Biology

ExoU is a potent intracellular phospholipase

H Sato et al.

MOLECULAR MICROBIOLOGY (2004)

Article Biochemistry & Molecular Biology

Pseudomonas aeruginosa exotoxin A induces human mast cell apoptosis by a caspase-8 and -3-dependent mechanism

CE Jenkins et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Immunology

Different domains of Pseudomonas aeruginosa exoenzyme S activate distinct TLRs

S Epelman et al.

JOURNAL OF IMMUNOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Paradoxical cAMP-induced lung endothelial hyperpermeability revealed by Pseudomonas aeruginosa ExoY

SL Sayner et al.

CIRCULATION RESEARCH (2004)

Review Biochemistry & Molecular Biology

The role of pyocyanin in Pseudomonas aeruginosa infection

GW Lau et al.

TRENDS IN MOLECULAR MEDICINE (2004)

Article Immunology

Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice

GW Lau et al.

INFECTION AND IMMUNITY (2004)

Article Biochemistry & Molecular Biology

A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses

FKM Chan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Human targets of Pseudomonas aeruginosa pyocyanin

HM Ran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Biochemistry & Molecular Biology

Phagocytosis of apoptotic cells and the resolution of inflammation

P Maderna et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2003)

Review Biochemistry & Molecular Biology

Promises and pitfalls of Pseudomonas aeruginosa lipopolysaccharide as a vaccine antigen

GB Pier

CARBOHYDRATE RESEARCH (2003)

Article Biochemistry & Molecular Biology

A four-tiered transcriptional regulatory circuit controls flagellar biogenesis in Pseudomonas aeruginosa

N Dasgupta et al.

MOLECULAR MICROBIOLOGY (2003)

Article Biochemistry & Molecular Biology

Pseudomonas aeruginosa ExoT ADP-ribosylates CT10 regulator of kinase (Crk) proteins

JJ Sun et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

O Micheau et al.

Article Cell Biology

Bordetella type III secretion induces caspase 1-independent necrosis

KE Stockbauer et al.

CELLULAR MICROBIOLOGY (2003)

Review Oncology

Necrosis: a specific form of programmed cell death?

SY Proskuryakov et al.

EXPERIMENTAL CELL RESEARCH (2003)

Article Biochemistry & Molecular Biology

Intracellular localization modulates targeting of ExoS, a type III cytotoxin, to eukaryotic signalling proteins

KJ Pederson et al.

MOLECULAR MICROBIOLOGY (2002)

Review Cell Biology

Receptor downregulation and multivesicular-body sorting

DJ Katzmann et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Biochemistry & Molecular Biology

SycE allows secretion of YopE-DHFR hybrids by the Yersinia enterocolitica type III Ysc system

MF Feldman et al.

MOLECULAR MICROBIOLOGY (2002)

Article Pediatrics

Early infection and progression of cystic fibrosis lung disease

C Koch

PEDIATRIC PULMONOLOGY (2002)

Article Biochemistry & Molecular Biology

Small molecular weight secretory factors from Pseudomonas aeruginosa have opposite effects on IL-8 and RANTES expression by human airway epithelial cells

KG Leidal et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2001)

Article Multidisciplinary Sciences

Polymerization of a single protein of the pathogen Yersinia enterocolitica into needles punctures eukaryotic cells

E Hoiczyk et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Biotechnology & Applied Microbiology

Pseudomonas aeruginosa rhamnolipids:: biosynthesis and potential applications

RM Maier et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2000)

Article Immunology

Pseudomonas aeruginosa ExoT is a Rho GTPase-activating protein

R Krall et al.

INFECTION AND IMMUNITY (2000)

Review Oncology

Apoptosis in cancer

SW Lowe et al.

CARCINOGENESIS (2000)