期刊
JOURNAL OF CLINICAL MEDICINE
卷 11, 期 24, 页码 -出版社
MDPI
DOI: 10.3390/jcm11247276
关键词
magnetic resonance imaging; respiratory muscle; chest wall; diaphragm; respiratory function
资金
- National Key Technologies R & D Program Precision China
- National Natural Science Foundation of China
- [2021YFC2500700]
- [2016YFC0901101]
- [81870056]
Dynamic magnetic resonance imaging (D-MRI) can quantitatively study the characteristic of diaphragm and chest wall motion in Chinese people with normal lung function. The chest wall motion is prominent in the anteroposterior direction during both quiet and deep breathing, with the motions of diaphragm apex and posterior diaphragm more prominent than that of the anterior diaphragm. Smoking may affect respiratory muscle mobility.
Objective: We aimed to quantitatively study the characteristic of diaphragm and chest wall motion using free-breathing dynamic magnetic resonance imaging (D-MRI) in Chinese people with normal lung function. Methods: 74 male subjects (mean age, 37 +/- 11 years old) were prospectively enrolled, and they underwent high-resolution CT(HRCT), pulmonary functional tests (PFTs), and D-MRI in the same day. D-MRI was acquired with a gradient-echo sequence during the quiet and deep breathing. The motion of the diaphragm and chest wall were respectively assessed by measuring thoracic anteroposterior diameter (AP), left-right diameter (LR), cranial-caudal diameter (CC), and thoracic area ratios between end-inspiration and end-expiration. The effect of age, body mass index (BMI), and smoking on respiratory muscle function was also analyzed. Results: The mean ratio of right and left AP was greater than that of LR on three transversal planes during both quiet and deep breathing. The mean ratio at the anterior diaphragm (AND, Quiet: 1.04 +/- 0.03; Deep: 1.15 +/- 0.09) was weaker than that of the apex (vs. APD, Quiet: 1.08 +/- 0.05, p < 0.001; Deep: 1.29 +/- 0.12, p < 0.001) and posterior diaphragm (vs. POD, Quiet: 1.09 +/- 0.04, p < 0.001; Deep: 1.30 +/- 0.12, p < 0.001) both in quiet and deep breathing. Compared with non-smokers, the left AP and thoracic area ratios in smokers were significantly decreased (p < 0.05). However, the ratios of AP, LR, CC, and thoracic area on each plane were similar among groups in different age and BMI. Conclusions: During both quiet and deep breathing, the chest wall motion is prominent in the anteroposterior direction. The motions of diaphragm apex and posterior diaphragm were more prominent than that of the anterior diaphragm. Smoking may affect the respiratory muscle mobility. Dynamic MRI can quantitatively evaluate the motion of respiratory muscles.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据