Psychological Characteristics and Quality of Life of Patients with Upper and Lower Functional Gastrointestinal Disorders

Background: This study aimed to identify the differences in the psychological characteristics of the anatomical location of functional gastrointestinal disorders (FGIDs) and the factors that influence the quality of life (QOL). Methods: Altogether, 233 patients with FGIDs were classified into the upper gastrointestinal disorder (UGID; n = 175) group and the lower gastrointestinal disorder group (LGID; n = 58). Psychological characteristics and QOL were evaluated using the validated questionnaires. Results: The LGID group demonstrated higher scores in 'emotional depression' than the UGID group in depressive symptoms (t = -3.031, p < 0.01). A significant difference was observed between groups in 'significant others' in social supports (t = 2.254, p < 0.05). Significant differences were observed between the groups in hardiness (t = 2.259, p < 0.05) and persistence (t = 2.526, p < 0.05) in resilience, while the LGID group demonstrated significantly lower scores than the UGID group in 'negative affectivity' in type-D personality (t = -1.997, p < 0.05). Additionally, the LGID group demonstrated lower QOL than the UGID group (t = 2.615, p < 0.05). The stepwise regression analysis on QOL involved depression, resilience, social support, and childhood trauma, which accounted for 48.4% of the total QOL explanatory variance. Conclusions: Psychological characteristics and QOL significantly differed when FGIDs were classified according to anatomical location. Thus, psychological interventions customized for each type of FGIDs may be necessary for effective treatment.

Automated summary

This study aimed to investigate the differences in psychological characteristics and factors influencing quality of life (QOL) based on the anatomical location of functional gastrointestinal disorders (FGIDs). The study found that the lower gastrointestinal disorder (LGID) group had higher scores in 'emotional depression' and lower QOL compared to the upper gastrointestinal disorder (UGID) group. Significant differences were also observed in resilience, social support, and childhood trauma. These findings highlight the importance of personalized psychological interventions for effective treatment of FGIDs.