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Article
Critical Care Medicine
Lixue Huang et al.
Summary: With the ongoing COVID-19 pandemic, a study was conducted to characterize the longitudinal evolution of health outcomes in hospitalized survivors of COVID-19 over a period of 2 years. The study found that although most survivors recovered and returned to work within 2 years, a significant proportion of them experienced persistent symptoms and health problems. These findings emphasize the need for further research and interventions to understand and reduce the risk of long-term COVID-19.
LANCET RESPIRATORY MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Valentina O. Puntmann et al.
Summary: Cardiac symptoms are a common late complication of COVID-19 infection in previously healthy individuals. Ongoing inflammatory cardiac involvement may explain the persistence of these symptoms, and magnetic resonance imaging and measurement of cardiac injury biomarkers can assist in detecting this inflammation.
Article
Microbiology
Richa Batra et al.
Summary: This study compares the molecular characteristics of COVID-19-induced ARDS and bacterial sepsis-induced ARDS. The findings uncover differences between the two etiologies and suggest potential therapeutic interventions. Additionally, the study examines the clinical manifestations of the two types of ARDS, identifying features associated with acute kidney injury and thrombocytosis. The research provides valuable insights into the pathophysiological processes of ARDS and offers new possibilities for therapeutic interventions.
Article
Critical Care Medicine
Martin S. Winkler et al.
Summary: A clear indication for the use of glucocorticosteroids (GCs) in severe COVID-19 has been established, potentially leading to a wider use of GCs in critical illnesses. To better understand the heterogeneity of critical illness and optimize the use of GCs within the precision medicine approach, this study formulates ten major questions that need to be answered.
Review
Critical Care Medicine
Allan E. Stolarski et al.
Summary: Research findings suggest that the levels of cytokines vary among different clinical conditions, indicating a lack of clear correlation between the conditions and the levels of cytokines.
Review
Critical Care Medicine
Marcin F. Osuchowski et al.
Summary: The zoonotic SARS-CoV-2 virus causing COVID-19 has devastating consequences worldwide, affecting primarily the respiratory system but also leading to long-term complications. Understanding the pathophysiology and immune response of COVID-19 is crucial for optimizing patient care and treatment strategies.
LANCET RESPIRATORY MEDICINE
(2021)
Review
Medicine, General & Internal
Martin S. Winkler et al.
Summary: Animal models have played a crucial role in medical research, especially in studying the novel coronavirus. Apart from clinical studies, these models have provided significant support for COVID-19 drug and vaccine development. During pandemics, optimizing the synergy between preclinical and clinical domains is essential for efficient resource utilization.
Article
Medicine, General & Internal
Mervyn Singer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2016)
Article
Critical Care Medicine
Marcin F. Osuchowski et al.
