Structural Advancement in Shoc2-MAPK Signaling Pathways in the Treatment of Cancer and Other Diseases

The structural advancement in Shoc, a prototypical Leucine rich protein, involved in MAPK pathway has added a new dimension in the development of drugs and therapeutics in treatment of cancer and other diseases. Here we have used computational studies to show that Shoc2 protein likely exhibits a dimer or even higher order oligomer structure during its scaffolding activity. The new perspective needs to be further explored for development of effective treatment against cancer, and other diseases.

Automated summary

The structural advancement in Shoc2 protein suggests that it may exhibit a dimer or higher order oligomer structure during its scaffolding activity, providing a new perspective for drug development in treating cancer and other diseases.