期刊
CHEMISTRYSELECT
卷 8, 期 5, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.202204294
关键词
Tetrazole derivatives; Pd-catalyst; MCR reactions; isocyanide insertion; antifungal activities
A straightforward method for the construction of tetrazole derivatives was achieved through Pd-catalyzed isocyanide insertion reactions, providing an extension for the response of multi-molecule isocyanides. The Ugi-N-3 reaction was introduced to enrich the diversity of skeleton structures. The commercially available starting materials and moderate to good yields make this method a valuable tool for generating N-containing heterocyclic compounds.
Herein, a straightforward method for the construction of tetrazole derivatives has been achieved through Pd-catalyzed isocyanide insertion reactions, which is a good extension for the response of multi-molecule isocyanides. The Ugi-N-3 reaction was introduced to the transformation to enrich the diversity of skeleton structures. The commercially available starting materials and moderate to good yields make this method a valuable tool for generating N-containing heterocyclic compounds.
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