Catalyst- and Solvent-Free Hydrophosphorylation of Aldimines with Secondary Phosphine Chalcogenides: Synthesis of Tertiary α-Aminophosphine Oxides, Sulfides and Selenides

Secondary phosphine chalcogenides mildly (no catalysts and solvents, 20-65 degrees C, 0.25-65.5 h) react with aldimines to deliver the hitherto unknown alpha-aminophosphine oxides, sulfides and selenides in good to excellent yields.

Automated summary

In this study, secondary phosphine chalcogenides reacted mildly with aldimines (without catalysts and solvents, at temperatures of 20-65 degrees Celsius for 0.25-65.5 hours) to yield previously unknown alpha-aminophosphine oxides, sulfides, and selenides in good to excellent yields.