4.7 Article

Oral administration of VDAC1-derived small molecule peptides increases circulating testosterone levels in male rats

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Treatment of Men with Central Hypogonadism: Alternatives for Testosterone Replacement Therapy

Veerle Ide et al.

Summary: Central hypogonadism is a clinical condition characterized by sexual symptoms and low testosterone levels due to impaired hypothalamus or pituitary function. Testosterone replacement therapy (TRT) is the standard treatment, but not recommended for men wishing to preserve fertility or those with certain health conditions. Alternative treatments such as gonadotropins, clomiphene citrate, and tamoxifen may be considered, although more research is needed on their efficacy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Urology & Nephrology

Advances in stem cell research for the treatment of primary hypogonadism

Lu Li et al.

Summary: In Leydig cell dysfunction, treatment with testosterone replacement therapy (TRT) can lead to adverse effects such as infertility. Stem-cell-based therapy shows promise in re-establishing testosterone-producing cell lineages for transplantation therapy.

NATURE REVIEWS UROLOGY (2021)

Review Andrology

Late-onset hypogonadism: metabolic impact

M. Grossmann et al.

ANDROLOGY (2020)

Review Andrology

Late-onset hypogonadism: a concept comes of age

E. Nieschlag

ANDROLOGY (2020)

Review Andrology

Testosterone replacement therapy

Arcangelo Barbonetti et al.

ANDROLOGY (2020)

Article Endocrinology & Metabolism

A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal M

Ronald S. Swerdloff et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)

Review Andrology

Reflections on the T Trials

Ronald Swerdloff et al.

ANDROLOGY (2020)

Review Endocrinology & Metabolism

Aging and the Male Reproductive System

Jean-Marc Kaufman et al.

ENDOCRINE REVIEWS (2019)

Review Cardiac & Cardiovascular Systems

Testosterone replacement therapy and cardiovascular risk

Thiago Gagliano-Juca et al.

NATURE REVIEWS CARDIOLOGY (2019)

Review Reproductive Biology

Leydig cells: formation, function, and regulation

Barry R. Zirkin et al.

BIOLOGY OF REPRODUCTION (2018)

Article Endocrinology & Metabolism

Testosterone Therapy in Men With Hypogonadism: An Endocrine Society* Clinical Practice Guideline

Shalender Bhasin et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)

Article Cell Biology

Gonadotropin regulation by pulsatile GnRH: Signaling and gene expression

George A. Stamatiades et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2018)

Correction Biochemistry & Molecular Biology

UniProt: the universal protein knowledgebase (vol 45, pg D158, 2017)

Alexandre Renaux

NUCLEIC ACIDS RESEARCH (2018)

Review Urology & Nephrology

Alternatives to Testosterone Therapy: A Review

Eric M. Lo et al.

SEXUAL MEDICINE REVIEWS (2018)

Article Medicine, General & Internal

Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone

Matthew J. Budoff et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Article Behavioral Sciences

Hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes: sex differences in regulation of stress responsivity

Mario G. Oyola et al.

STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS (2017)

Review Pharmacology & Pharmacy

Emerging medication for the treatment of male hypogonadism

Aydogan Aydogdu et al.

EXPERT OPINION ON EMERGING DRUGS (2016)

Article Medicine, General & Internal

Adult-Onset Hypogonadism

Mohit Khera et al.

MAYO CLINIC PROCEEDINGS (2016)

Review Pharmacology & Pharmacy

A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives

Abdul Muheem et al.

SAUDI PHARMACEUTICAL JOURNAL (2016)

Article Multidisciplinary Sciences

PEPlife: A Repository of the Half-life of Peptides

Deepika Mathur et al.

SCIENTIFIC REPORTS (2016)

Review Andrology

Alternatives to testosterone replacement: testosterone restoration

Andrew McCullough

ASIAN JOURNAL OF ANDROLOGY (2015)

Article Chemistry, Medicinal

Best of Both Worlds: Combining Pharma Data and State of the Art Modeling Technology To Improve in Silico pKa Prediction

Robert Fraczkiewicz et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2015)

Article Pharmacology & Pharmacy

Risk of Myocardial Infarction in Older Men Receiving Testosterone Therapy

Jacques Baillargeon et al.

ANNALS OF PHARMACOTHERAPY (2014)

Article Reproductive Biology

Steroidogenesis in MA-10 Mouse Leydig Cells Is Altered via Fatty Acid Import into the Mitochondria1

Malena B. Rone et al.

BIOLOGY OF REPRODUCTION (2014)

Review Genetics & Heredity

Molecular regulation of hypothalamus-pituitary-gonads axis in males

Jia-Min Jin et al.

Article Geriatrics & Gerontology

Testosterone Induces Erythrocytosis via Increased Erythropoietin and Suppressed Hepcidin: Evidence for a New Erythropoietin/Hemoglobin Set Point

Eric Bachman et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)

Review Cell Biology

GnRH pulse frequency-dependent differential regulation of LH and FSH gene expression

Iain R. Thompson et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)

Article Medicine, General & Internal

Association of Testosterone Therapy With Mortality, Myocardial Infarction, and Stroke in Men With Low Testosterone Levels

Rebecca Vigen et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)

Article Urology & Nephrology

Anabolic Steroid Induced Hypogonadism in Young Men

Robert M. Coward et al.

JOURNAL OF UROLOGY (2013)

Article Urology & Nephrology

Outcomes of clomiphene citrate treatment in young hypogonadal men

Darren J. Katz et al.

BJU INTERNATIONAL (2012)

Article Urology & Nephrology

Clomiphene citrate is safe and effective for long-term management of hypogonadism

Daniel J. Moskovic et al.

BJU INTERNATIONAL (2012)

Article Endocrinology & Metabolism

Testosterone Treatment and Mortality in Men with Low Testosterone Levels

Molly M. Shores et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

Review Biochemistry & Molecular Biology

Cell-penetrating peptides: breaking through to the other side

Erez Koren et al.

TRENDS IN MOLECULAR MEDICINE (2012)

Article Endocrinology & Metabolism

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evidence from the European Male Ageing Study

Abdelouahid Tajar et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)

Review Biochemistry & Molecular Biology

VDAC, a multi-functional mitochondrial protein regulating cell life and death

Varda Shoshan-Barmatz et al.

MOLECULAR ASPECTS OF MEDICINE (2010)

Article Medicine, General & Internal

Adverse Events Associated with Testosterone Administration

Shehzad Basaria et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Review Biochemistry & Molecular Biology

Cholesterol transport in steroid biosynthesis: Role of protein-protein interactions and implications in disease states

Malena B. Rone et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)

Article Endocrinology & Metabolism

The biology of gonadotroph regulation

Nick A. Ciccone et al.

CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2009)

Article Biochemistry & Molecular Biology

Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein

Mahuya Bose et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

Jun Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Endocrinology & Metabolism

Effects of testosterone on sexual function in men: results of a meta-analysis

AM Isidori et al.

CLINICAL ENDOCRINOLOGY (2005)

Article Endocrinology & Metabolism

Low-dose human chorionic gonadotropin maintains intratesticular testosterone in normal men with testosterone-induced gonadotropin suppression

AD Coviello et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Article Endocrinology & Metabolism

Short-term aromatase-enzyme blockade unmasks impaired feedback adaptations in luteinizing hormone and testosterone secretion in older men

JD Veldhuis et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)

Article Multidisciplinary Sciences

Effect of long-term treatment with low doses of the LHRH antagonist Cetrorelix on pituitary receptors for LHRH and gonadal axis in male and female rats

JE Horvath et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Endocrinology & Metabolism

Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels

BZ Leder et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)

Review Endocrinology & Metabolism

Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones

AH Payne et al.

ENDOCRINE REVIEWS (2004)