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Early and precocious puberty during the COVID-19 pandemic

FRONTIERS IN ENDOCRINOLOGY (2023)

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Summary: This review synthesizes the literature on the potential influence of the COVID-19 pandemic on sleep quality in children and adolescents. The findings suggest that during the pandemic, there was an increase in sleep duration, late bedtimes, and poor sleep quality among children and adolescents. These alterations were related to changes in family routines.

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Impact of COVID-19 Lockdown on Body Weight, Eating Habits, and Physical Activity of Jordanian Children and Adolescents

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Summary: The study found that during the COVID-19 lockdown period, Jordanian youth experienced a significant increase in body weight and body mass index, decreased physical activity, increased screen time, and increased food intake.

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Impact of COVID-19 lockdown on idiopathic central precocious puberty - Experience from an Indian centre

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Summary: There was an increase in referrals for precocious puberty and diagnoses of idiopathic central precocious puberty (iCPP) during the COVID lockdown. The increase was higher in girls. There were no significant differences in anthropometric measurements between the two groups, but children in the lockdown group had significantly advanced bone age.

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Difference of Precocious Puberty Between Before and During the COVID-19 Pandemic: A Cross-Sectional Study Among Shanghai School-Aged Girls

Yao Chen et al.

Summary: This study compared the incidence rates and clinical features of precocious girls before and during the COVID-19 pandemic among Shanghai school-aged girls. The results showed that the monthly incidence rates of precocious puberty were higher during the pandemic, and the serum concentrations of MKRN3 and ghrelin were lower in the pandemic group. This suggests that COVID-19 may affect the regulatory mechanisms of puberty.

FRONTIERS IN ENDOCRINOLOGY (2022)

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Has the Frequency of Precocious Puberty and Rapidly Progressive Early Puberty Increased in Girls During the COVID-19 Pandemic?

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Analysis of the Incidence and Risk Factors of Precocious Puberty in Girls during the COVID-19 Pandemic

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Summary: Home quarantine during the global COVID-19 pandemic has led to an increase in precocious puberty among girls, with factors such as increased screen time, decreased exercise, and unhealthy diet playing a role.

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An increasing tendency of precocious puberty among Korean children from the perspective of COVID-19 pandemic effect

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Summary: This study investigates the current status and treatment costs of precocious puberty (PP) in Korea from 2016 to 2021, finding an increasing number of diagnosed cases and medical expenses. The study also reveals a rising incidence of PP in males, possibly due to the impact of the COVID-19 pandemic and increased awareness. Further research is needed to determine the causes of the increasing prevalence of PP.

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Status of Central Precocious Puberty Cases at the Onset of Coronavirus Disease 2019 Pandemic: A Single-Center Experience

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Central precocious puberty during COVID-19 pandemic and sleep disturbance: an exploratory study

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Summary: The study reveals an increased incidence of CPP after COVID-19 lockdown measures. Additionally, CPP patients showed higher rates of sleep disturbances and a later bedtime compared to healthy controls.

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Reduction in pediatric growth hormone deficiency and increase in central precocious puberty diagnoses during COVID 19 pandemics

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Summary: This study evaluated the impact of the COVID-19 pandemic on pediatric endocrinology and found important results. During the pandemic, there was a significant reduction in tests for growth hormone deficiency (GHD) and an increase in the diagnosis of central precocious puberty (CPP). These findings suggest the need to closely monitor children's growth during isolation and consider the potential effects of lockdown restrictions on CPP.

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Lifestyle Changes and Determinants of Children's and Adolescents' Body Weight Increase during the First COVID-19 Lockdown in Greece: The COV-EAT Study

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Endocrine-disrupting chemicals and their effects on puberty

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COVID-19 and central nervous system interplay: A big picture beyond clinical manifestation

Sutapa Som Chaudhury et al.

Summary: The COVID-19 pandemic caused by SARS-CoV-2 presents a significant threat globally, with infected individuals displaying a range of clinical symptoms. The involvement of the central nervous system in disease progression is crucial, with its immunological responses and interactions with other major organs not fully understood.

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Summary: COVID-19 is often associated with olfactory dysfunction, providing a research opportunity to study the natural course of this neurological finding. However, limited by sample sizes and lack of advanced neuroimaging data, there is still a substantial gap in knowledge regarding the mechanisms of olfactory impairment. Persistent olfactory deficits post-SARS-CoV-2 infection could potentially be a marker for increased long-term risk of neurological disease.

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