4.7 Editorial Material

Should I stay, or should I go? Gene retention in organellar genomes

期刊

CELL SYSTEMS
卷 13, 期 11, 页码 861-863

出版社

CELL PRESS
DOI: 10.1016/j.cels.2022.10.006

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资金

  1. Training Program in Environmental Toxicology (NIH) [T32 ES007028]
  2. National Defense Science & Engineering Graduate Fellowship, United States
  3. NIH [R01 GM123260, R35 GM145378]
  4. Department of Defense's Congressionally Directed Medical Research Program [PR170792]

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This study used bioinformatic data and modeling to identify universal rules that determine organellar gene retention.
Mitochondria and plastids retain their own small but essential genomes. However, the evolutionary pressures that determine whether a gene is retained in organellar DNA or exported to the host nuclear genome remain unclear. A new study in Cell Systems addresses this knowledge gap using bioinformatic data and modeling to identify universal rules that determine organellar gene retention.

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