4.7 Article

Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cell Biology

The assembly, regulation and function of the mitochondrial respiratory chain

Irene Vercellino et al.

Summary: The mitochondrial oxidative phosphorylation system is essential for cellular metabolism, driving ATP production through the electron transport chain. Recent studies have provided insights into the organization, assembly, and mechanisms of the respiratory complexes, including the formation of larger assemblies such as respiratory supercomplexes, and their roles in physiology.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2022)

Article Endocrinology & Metabolism

Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat

Josef Oeckl et al.

Summary: We explore different potential sources of UCP1-independent thermogenesis and identify a futile ATP-consuming triglyceride/fatty acid cycle as the main contributor to cellular heat production in brown adipocytes lacking UCP1. We uncover the mechanism on a molecular level and pinpoint the key enzymes involved using pharmacological and genetic interference.

MOLECULAR METABOLISM (2022)

Article Cell Biology

Two independent respiratory chains adapt OXPHOS performance to glycolytic switch

Erika Fernandez-Vizarra et al.

Summary: This study reveals the existence of two separate organizations, C-MRC and S-MRC, in human cells and postmitotic tissues. These organizations are regulated by different COX7A isoforms and the activation state of PDC, and play distinct roles under different metabolic conditions.

CELL METABOLISM (2022)

Article Endocrinology & Metabolism

COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

Giorgia Benegiamo et al.

Summary: This study identifies genetic variants of the mitochondrial supercomplex assembly factor COX7A2L that promote cardiorespiratory fitness in mice and humans. The increased expression of COX7A2L leads to more supercomplexes and improved respiration, as well as lower body fat and enhanced cardiorespiratory fitness.

NATURE METABOLISM (2022)

Article Genetics & Heredity

Loss of α-actinin-3 during human evolution provides superior cold resilience and muscle heat generation

Victoria L. Wyckelsma et al.

Summary: Humans lacking alpha-actinin-3 (XX) show improved cold tolerance by maintaining core body temperature during cold-water immersion, which is attributed to changes in skeletal muscle thermogenesis, with a shift towards more slow-twitch isoforms of myosin heavy chain and sarcoplasmic reticulum proteins.

AMERICAN JOURNAL OF HUMAN GENETICS (2021)

Article Endocrinology & Metabolism

A pyrexic effect of FGF21 independent of energy expenditure and UCP1

Petr Zouhar et al.

Summary: Administration of FGF21 to mice increases body temperature independently of energy expenditure, with effects more pronounced at lower ambient temperatures. FGF21 enhances UCP1 protein content in brown adipose tissue and increases energy expenditure through adrenergic stimulation, while reducing heat loss in mice lacking UCP1. Limited body weight-lowering effects of FGF21 may be expected due to its primary effect on body temperature rather than energy expenditure.

MOLECULAR METABOLISM (2021)

Article Physiology

Body temperature control in rats by muscle tone during rest or sleep

Terje Lomo et al.

ACTA PHYSIOLOGICA (2020)

Review Biology

Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis

Naresh C. Bal et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2020)

Article Multidisciplinary Sciences

Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

Susanne Keipert et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish

Carolina Garcia-Poyatos et al.

EMBO REPORTS (2020)

Article Multidisciplinary Sciences

Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Qpool

Enrique Calvo et al.

SCIENCE ADVANCES (2020)

Article Biochemistry & Molecular Biology

Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

Trine S. Nicolaisen et al.

FASEB JOURNAL (2020)

Article Multidisciplinary Sciences

The paradoxical lean phenotype of hypothyroid mice is marked by increased adaptive thermogenesis in the skeletal muscle

Rachel R. Kaspari et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Physiology

Role of Cytochrome c Oxidase Nuclear-Encoded Subunits in Health and Disease

Kristyna Cunatova et al.

PHYSIOLOGICAL RESEARCH (2020)

Review Biochemistry & Molecular Biology

Energy metabolism in cachexia

Maria Rohm et al.

EMBO REPORTS (2019)

Article Multidisciplinary Sciences

Muscle nonshivering thermogenesis in a feral mammal

Julia Nowack et al.

SCIENTIFIC REPORTS (2019)

Article Multidisciplinary Sciences

Thermal stress induces glycolytic beige fat formation via a myogenic state

Yong Chen et al.

NATURE (2019)

Article Endocrinology & Metabolism

Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity

Lawrence Kazak et al.

NATURE METABOLISM (2019)

Article Biochemistry & Molecular Biology

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

Jasmine Chong et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Physiology

Sarcolipin Makes Heat, but Is It Adaptive Thermogenesis?

Kevin L. Campbell et al.

FRONTIERS IN PHYSIOLOGY (2018)

Article Medicine, Research & Experimental

Human adipose beiging in response to cold and mirabegron

Brian S. Finlin et al.

JCI INSIGHT (2018)

Article Endocrinology & Metabolism

Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype

P. Flachs et al.

INTERNATIONAL JOURNAL OF OBESITY (2017)

Article Biochemistry & Molecular Biology

Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice

Naresh C. Bal et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Article Multidisciplinary Sciences

Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity

Qiantao Zheng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Cold acclimation causes fiber type-specific responses in glucose and fat metabolism in rat skeletal muscles

Diane M. Sepa-Kishi et al.

SCIENTIFIC REPORTS (2017)

Review Biochemistry & Molecular Biology

Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity

Jian Liu et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2017)

Article Endocrinology & Metabolism

Adaptive facultative diet-induced thermogenesis in wild-type but not in UCP1-ablated mice

Gabriella von Essen et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2017)

Article Biochemistry & Molecular Biology

Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function

Naresh C. Bal et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Endocrinology & Metabolism

Regionalization of Browning Revealed by Whole Subcutaneous Adipose Tissue Imaging

Corinne Barreau et al.

OBESITY (2016)

Article Endocrinology & Metabolism

Integration of body temperature into the analysis of energy expenditure in the mouse

Gustavo Abreu-Vieira et al.

MOLECULAR METABOLISM (2015)

Article Radiology, Nuclear Medicine & Medical Imaging

18F-FDG PET/CT Monitoring of β3 Agonist-Stimulated Brown Adipocyte Recruitment in White Adipose Tissue

Jin Won Park et al.

JOURNAL OF NUCLEAR MEDICINE (2015)

Article Biochemistry & Molecular Biology

ROS production in brown adipose tissue mitochondria: The question of UCP1-dependence

Irina G. Shabalina et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2014)

Article Biochemistry & Molecular Biology

Brown adipose tissue dynamics in wild-type and UCP1-knockout mice: in vivo insights with magnetic resonance

Kirsten Grimpo et al.

JOURNAL OF LIPID RESEARCH (2014)

Article Nutrition & Dietetics

Effects of ambient temperature on mechanomyography of resting quadriceps muscle

William P. McKay et al.

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2013)

Article Biochemistry & Molecular Biology

Quantitative calculation of the role of the Na+,K+-ATPase in thermogenesis

Ronald J. Clarke et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2013)

Article Biochemistry & Molecular Biology

Stimulation of mitochondrial oxidative capacity in white fat independent of UCP1: A key to lean phenotype

Pavel Flachs et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

Article Biochemistry & Molecular Biology

Tissue-specific Role of the Na,K-ATPase α2 Isozyme in Skeletal Muscle

Tatiana L. Radzyukevich et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

Esther Lapuente-Brun et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle

Kazuhiro Ikeda et al.

NATURE COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

Jun Wu et al.

Article Biochemistry & Molecular Biology

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

Naresh C. Bal et al.

NATURE MEDICINE (2012)

Article Cell Biology

Evaluation of basic mitochondrial functions using rat tissue homogenates

Alena Pecinova et al.

MITOCHONDRION (2011)

Article Physiology

Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice

Carola W. Meyer et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)

Article Physiology

Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects

Rochelle Goldsmith et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)

Review Cell Biology

Brown Fat and the Myth of Diet-Induced Thermogenesis

Leslie P. Kozak

CELL METABOLISM (2010)

Article Endocrinology & Metabolism

Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance

Vladimir Kus et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)

Article Endocrinology & Metabolism

Individual thermogenic responses to mild cold and overfeeding are closely related

Sander L. J. Wijers et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Article Endocrinology & Metabolism

UCP1 is essential for adaptive adrenergic nonshivering thermogenesis

Valeria Golozoubova et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Article Endocrinology & Metabolism

Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress

J Ukropec et al.

ENDOCRINOLOGY (2006)

Review Physiology

Thermogenic mechanisms and their hormonal regulation

JE Silva

PHYSIOLOGICAL REVIEWS (2006)

Article Biochemistry & Molecular Biology

ELOVL3 is an important component for early onset of lipid recruitment in brown adipose tissue

R Westerberg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemical Research Methods

Blue native PAGE

Ilka Wittig et al.

NATURE PROTOCOLS (2006)

Article Medicine, Research & Experimental

Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight

M Rosenbaum et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Biochemistry & Molecular Biology

Development of cytochrome-c oxidase activity in rat heart

Z Drahota et al.

CELL BIOCHEMISTRY AND BIOPHYSICS (2005)

Article Pharmacology & Pharmacy

Percent relative cumulative frequency analysis in indirect calorimetry: application to studies of transgenic mice

M Riachi et al.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2004)

Review Physiology

Brown adipose tissue: Function and physiological significance

B Cannon et al.

PHYSIOLOGICAL REVIEWS (2004)

Article Endocrinology & Metabolism

White adipose tissue contributes to UCP1-independent thermogenesis

JG Granneman et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)

Article Medicine, Research & Experimental

Paradoxical resistance to diet-induced obesity in UCP1-deficient mice

XT Liu et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Article Multidisciplinary Sciences

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Y Minokoshi et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

V Golozoubova et al.

FASEB JOURNAL (2001)

Article Biochemistry & Molecular Biology

Effects of genetic background on thermoregulation and fatty acid-induced uncoupling of mitochondria in UCP1-deficient mice

WE Hofmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)