4.6 Article

BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson's disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Neurosciences

The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats

Natosha M. Mercado et al.

Summary: The study found that rats with the rs6265 SNP showed enhanced transplant efficacy and neurite outgrowth, but also experienced transplant-induced dyskinesias. This suggests that this common genetic mutation can affect transplant therapeutic efficacy and side effects development.

NEUROBIOLOGY OF DISEASE (2021)

Article Medicine, Research & Experimental

BDNF rs6265 Genotype Influences Outcomes of Pharmacotherapy and Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease

Caryl E. Sortwell et al.

Summary: The rs6265 polymorphism in the BDNF gene may be useful for predicting long-term response to drug therapy in Parkinson's disease patients and counseling them regarding the consideration of early subthalamic nucleus deep brain stimulation. Validation in a larger cohort of early-stage Parkinson's disease subjects is needed to confirm these findings.

NEUROMODULATION (2021)

Article Multidisciplinary Sciences

The GTEx Consortium atlas of genetic regulatory effects across human tissues

Francois Aguet et al.

SCIENCE (2020)

Article Clinical Neurology

BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease

D. Luke Fischer et al.

NEUROTHERAPEUTICS (2020)

Article Behavioral Sciences

BDNF genotype is associated with hippocampal volume in mild traumatic brain injury

J. P. Hayes et al.

GENES BRAIN AND BEHAVIOR (2018)

Article Clinical Neurology

Dopamine receptors and BDNF-haplotypes predict dyskinesia in Parkinson's disease

Cynthia D. J. Kusters et al.

PARKINSONISM & RELATED DISORDERS (2018)

Article Clinical Neurology

Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease

D. Luke Fischer et al.

PARKINSONISM & RELATED DISORDERS (2018)

Article Psychiatry

BDNF promoter methylation and genetic variation in late-life depression

V. Januar et al.

TRANSLATIONAL PSYCHIATRY (2015)

Article Clinical Neurology

Pharmacogenetic considerations in the treatment of Parkinson's disease

Mateusz Kurzawski et al.

NEURODEGENERATIVE DISEASE MANAGEMENT (2015)

Article Clinical Neurology

BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease

T. Foltynie et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2009)

Article Clinical Neurology

Levodopa Response in Early Parkinson's Disease

Robert A. Hauser et al.

MOVEMENT DISORDERS (2009)