4.8 Review

Antiviral response within different cell types of the CNS

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response

Olus Uyar et al.

Summary: A new microglia-like state with specific gene expressions associated with neutrophils has been identified in herpes simplex encephalitis (HSE), suggesting an exacerbated CNS inflammation due to infected microglia/microglia-like cells producing increased IL-1β through NLRP3-inflammasome-mediated pathway.

JOURNAL OF NEUROINFLAMMATION (2022)

Review Immunology

The roles of microglia in viral encephalitis: from sensome to therapeutic targeting

Chintan Chhatbar et al.

Summary: Microglia play a crucial role in viral encephalitis, promoting immune responses to protect the host but also potentially causing damage to neurons. Further research is needed to understand the dysregulation of microglia-T cell interactions.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

Article Multidisciplinary Sciences

Dysregulation of brain and choroid plexus cell types in severe COVID-19

Andrew C. Yang et al.

Summary: This study found that patients with COVID-19 exhibited widespread cellular perturbations in the brain, including the relay of peripheral inflammation into the brain by choroid plexus barrier cells and infiltration of peripheral T cells. Additionally, COVID-19 affected synaptic signaling of upper-layer excitatory neurons linked to cognitive function.

NATURE (2021)

Article Multidisciplinary Sciences

Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

E. A. Monson et al.

Summary: Lipid droplets (LDs) are critical in enhancing modulation of IFN, controlling viral replication, and facilitating early antiviral immune response, marking a paradigm shift in understanding the molecular mechanisms of effective antiviral responses.

NATURE COMMUNICATIONS (2021)

Article Genetics & Heredity

Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19

John F. Fullard et al.

Summary: Despite the absence of detectable SARS-CoV-2 in the brain at the time of death, the findings suggest significant and persistent neuroinflammation in patients with acute COVID-19. Single-cell transcriptomics studies revealed transcriptional changes in various cell types in specific brain regions of COVID-19 patients, including cellular activation, mobility, and phagocytosis.

GENOME MEDICINE (2021)

Review Biotechnology & Applied Microbiology

Cell Type Specific Expression of Toll-Like Receptors in Human Brains and Implications in Alzheimer's Disease

Henriette R. Frederiksen et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Review Immunology

Interferon Control Of Neurotropic Viral Infections

Katelynn A. Milora et al.

TRENDS IN IMMUNOLOGY (2019)

Review Genetics & Heredity

Deciphering Brain Complexity Using Single-cell Sequencing

Quanhua Mu et al.

GENOMICS PROTEOMICS & BIOINFORMATICS (2019)

Review Clinical Neurology

Emerging and re-emerging viruses affecting the nervous system

Uta Meyding-Lamade et al.

NEUROLOGICAL RESEARCH AND PRACTICE (2019)

Article Multidisciplinary Sciences

Brain Cell Type Specific Gene Expression and Co-expression Network Architectures

Andrew T. McKenzie et al.

SCIENTIFIC REPORTS (2018)

Article Virology

New advances in CNS immunity against viral infection

Monica Manglani et al.

CURRENT OPINION IN VIROLOGY (2018)

Review Anatomy & Morphology

Cell Densities in the Mouse Brain: A Systematic Review

Daniel Keller et al.

FRONTIERS IN NEUROANATOMY (2018)

Article Multidisciplinary Sciences

The brain parenchyma has a type I interferon response that can limit virus spread

Eugene Drokhlyansky et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Medicine, Research & Experimental

Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection

Brian P. Daniels et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Neurosciences

Human microglia and astrocytes express cGAS-STING viral sensing components

Austin M. Jeffries et al.

NEUROSCIENCE LETTERS (2017)

Review Neurosciences

Keeping it in check: chronic viral infection and antiviral immunity in the brain

Katelyn D. Miller et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

Zika virus cell tropism in the developing human brain and inhibition by azithromycin

Hanna Retallack et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS

Line S. Reinert et al.

NATURE COMMUNICATIONS (2016)

Article Medicine, General & Internal

Zika Virus Strains Potentially Display Different Infectious Profiles in Human Neural Cells

Yannick Simonin et al.

EBIOMEDICINE (2016)

Article Immunology

Homeostatic interferon expression in neurons is sufficient for early control of viral infection

Sarah E. Cavanaugh et al.

JOURNAL OF NEUROIMMUNOLOGY (2015)

Article Multidisciplinary Sciences

HIV-1 increases TLR responses in human primary astrocytes

M. Jesus Serramia et al.

SCIENTIFIC REPORTS (2015)

Article Biotechnology & Applied Microbiology

Infection and injury of human astrocytes by tick-borne encephalitis virus

Martin Palus et al.

JOURNAL OF GENERAL VIROLOGY (2014)

Review Biochemistry & Molecular Biology

New Function of Type I IFN: Induction of Autophagy

Hana Schmeisser et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2014)

Article Virology

Long-Distance Interferon Signaling within the Brain Blocks Virus Spread

Anthony N. van den Pol et al.

JOURNAL OF VIROLOGY (2014)

Article Multidisciplinary Sciences

Tick-Borne Encephalitis Virus Infects Rat Astrocytes but Does Not Affect Their Viability

Maja Potokar et al.

PLOS ONE (2014)

Review Immunology

Toll-like receptor signaling pathways

Takumi Kawasaki et al.

FRONTIERS IN IMMUNOLOGY (2014)

Article Gastroenterology & Hepatology

Epidermal Growth Factor Receptor Signaling Impairs the Antiviral Activity of Interferon-Alpha

Joachim Lupberger et al.

HEPATOLOGY (2013)

Article Immunology

Theiler's murine encephalomyelitis virus induced phenotype switch of microglia in vitro

I. Gerhauser et al.

JOURNAL OF NEUROIMMUNOLOGY (2012)

Review Neurosciences

Immune surveillance in the central nervous system

Shalina S. Ousman et al.

NATURE NEUROSCIENCE (2012)

Article Biochemistry & Molecular Biology

Epidermal Growth Factor Receptor Is Essential for Toll-Like Receptor 3 Signaling

Michifumi Yamashita et al.

SCIENCE SIGNALING (2012)

Review Immunology

Toll-like receptor (TLR) and inflammasome actions in the central nervous system

Richa Hanamsagar et al.

TRENDS IN IMMUNOLOGY (2012)

Article Cell Biology

The regulation of autophagy - unanswered questions

Yongqiang Chen et al.

JOURNAL OF CELL SCIENCE (2011)

Article Virology

Interferon-stimulated genes and their antiviral effector functions

John W. Schoggins et al.

CURRENT OPINION IN VIROLOGY (2011)

Article Microbiology

Autophagy Protects against Sindbis Virus Infection of the Central Nervous System

Anthony Orvedahl et al.

CELL HOST & MICROBE (2010)

Review Virology

Recognition of viral nucleic acids in innate immunity

Mitsutoshi Yoneyama et al.

REVIEWS IN MEDICAL VIROLOGY (2010)

Article Microbiology

Bid Regulates the Pathogenesis of Neurotropic Reovirus

Pranav Danthi et al.

PLOS PATHOGENS (2010)

Review Cell Biology

Molecular mechanisms of mTOR-mediated translational control

Xiaoju Max Ma et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Role of the At pathway in mRNA translation of interferon-stimulated genes

Surinder Kaur et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Immunology

Interferon-inducible antiviral effectors

Anthony J. Sadler et al.

NATURE REVIEWS IMMUNOLOGY (2008)

Article Multidisciplinary Sciences

Neurons produce type I interferon during viral encephalitis

Sophie Delhaye et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Neurosciences

Differential responses of human brain cells to West Nile virus infection

MCJ Cheeran et al.

JOURNAL OF NEUROVIROLOGY (2005)

Article Cell & Tissue Engineering

NTera2: A model system to study dopaminergic differentiation of human embryonic stem cells

CM Schwartz et al.

STEM CELLS AND DEVELOPMENT (2005)

Article Neurosciences

ATP mediates rapid microglial response to local brain injury in vivo

D Davalos et al.

NATURE NEUROSCIENCE (2005)

Review Immunology

Mechanisms of type-I- and type-II-interferon-mediated signalling

LC Platanias

NATURE REVIEWS IMMUNOLOGY (2005)

Article Immunology

Preferential expression and function of Toll-like receptor 3 in human astrocytes

C Farina et al.

JOURNAL OF NEUROIMMUNOLOGY (2005)

Article Biochemistry & Molecular Biology

Glial cells

KR Jessen

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2004)

Article Clinical Neurology

Broad expression of Toll-like receptors in the human central nervous system

M Bsibsi et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2002)

Article Biochemistry & Molecular Biology

Interferon-α promotes survival of human primary B-lymphocytes via phosphatidylinositol 3-kinase

K Ruuth et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Article Medicine, Research & Experimental

NF-kappa B: a key role in inflammatory diseases

PP Tak et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)