Mycosynthesis, Characterization of Zinc Oxide Nanoparticles, and Its Assessment in Various Biological Activities

In recent years, nanotechnology has become one of the emerging fields of nanoparticle synthesis using biological processes. The use of mushroom extract is one of the most important methods for biological synthesis due to the presence of abundant biologically active compounds. In this study, Zinc Oxide nanoparticles (ZnO NPs) were synthesized using Daedalea sp. mushroom extract. The nanoparticles had an average size of 14.58 nm and irregular morphology, which shows its prominent character. Various analytical techniques including FTIR, X-ray diffraction, EDX, and UV-Vis spectrum showed a broad absorption between 350 and 380 nm, which indicates the synthesis of ZnO NPs. The characterized NPs were exploited for a wide range of biomedical applications including biocompatibility, antifungal, antileishmanial, and antibacterial studies. The ZnO nanoparticles showed a strong antibacterial effect against gram-positive (Klesbsilla pneumonia and Staphylococcus aureus) and gram-negative (Eschericia coli and Pseudomonas aeruginosa) bacteria. Furthermore, the ZnO nanoparticles also showed a high antifungal effect against Aspergillus niger fungus.

Automated summary

In recent years, nanotechnology has emerged as an important field for the synthesis of nanoparticles using biological processes. Mushroom extract is a prominent method in biological synthesis due to its abundance of biologically active compounds. In this study, Zinc Oxide nanoparticles (ZnO NPs) were successfully synthesized using Daedalea sp. mushroom extract. The nanoparticles exhibited irregular morphology, with an average size of 14.58 nm. Various analytical techniques confirmed the synthesis of ZnO NPs, which were then tested for biocompatibility, antifungal, antileishmanial, and antibacterial activities. The ZnO nanoparticles showed strong antibacterial effects against both gram-positive and gram-negative bacteria, as well as high antifungal activity against Aspergillus niger fungus.