☆ 4.8 Review

Artificial Olfactory Biohybrid System: An Evolving Sense of Smell

ADVANCED SCIENCE (2023)

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Article Engineering, Environmental

Nature, smells, and human wellbeing

Phoebe R. Bentley et al.

Summary: This article examines how smells experienced in woodlands contribute to wellbeing across four seasons. It shows that smells are associated with multiple wellbeing domains, both positively and negatively. By making the link between the spatiotemporal variability in biodiversity and wellbeing explicit, a new line of enquiry is unearthed.

AMBIO (2023)

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Article Biophysics

High-performance olfactory receptor-derived peptide sensor for trimethylamine detection based on Steglich esterification reaction and native chemical ligation connection

Zhi Wang et al.

Summary: A high-performance TMA sensor was developed using a chemical connection method to effectively load ORPs onto SWCNTs, achieving detection of TMA at concentrations as low as 0.01 parts per trillion, three orders of magnitude lower than previously reported. The sensor demonstrated excellent sensitivity, selectivity, and stability for TMA detection, showing great potential for applications in environmental safety, food quality evaluation, and healthcare.

BIOSENSORS & BIOELECTRONICS (2022)

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Review Chemistry, Multidisciplinary

Recent progress and growth in biosensors technology: A critical review

Utkarsh Chadha et al.

Summary: The crucial exploitation of biosensors has become dominant in various fields, including drug innovation, food safety, and ecological examination. The use of biological sensing elements as diagnostic tools has led to the development of specific and authoritative biosensors. Advances in biological methods and instrumentation have improved the responsiveness of biosensors, and the use of new tools like aptamers and antibodies has opened up possibilities for novel biosensors with high regenerative potentials. This review provides an overview of different types of biosensors and their applications, highlighting the future outlook of biosensor technology.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY (2022)

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Article Computer Science, Artificial Intelligence

Subspace alignment based on an extreme learning machine for electronic nose drift compensation

Jia Yan et al.

Summary: This paper proposes a novel subspace alignment extreme learning machine (SAELM) for drift compensation in electronic nose systems, which minimizes both the geometric and statistical distributions between different domains, enhances the dependency between features and labels, and leverages l(2),(1) norm to constrain the output weights of ELM for better feature extraction capability in subspace learning. Extensive experiments have shown that the proposed SAELM method yields the greatest improvements on E-nose drift datasets.

KNOWLEDGE-BASED SYSTEMS (2022)

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Review Biochemistry & Molecular Biology

Resistive Chemosensors for the Detection of CO Based on Conducting Polymers and Carbon Nanocomposites: A Review

Mihaela Savin et al.

Summary: Nanocomposite materials have been widely used in various applications, and their potential in CO detection is of particular interest. Combining polymers with carbon materials can improve the analytical parameters of sensors. The CO reaction mechanism may differ when measured in mixtures with other gases, resulting in lower sensitivity. This study provides a comprehensive description of carbon nanostructure-based chemosensors, covering sensing mechanisms, water solution strategies, and morphology choices.

MOLECULES (2022)

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Article Nanoscience & Nanotechnology

Odorant binding proteins from Hermetia illucens: potential sensing elements for detecting volatile aldehydes involved in early stages of organic decomposition

Marisa Nardiello et al.

Summary: Organic decomposition processes release volatile organic compounds (VOCs) that can be detected by insects through odor recognition mechanisms. In this study, aldehydes were successfully detected using the odor recognition system of Hermetia illucens, expanding gas sensing technology.

NANOTECHNOLOGY (2022)

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Review Chemistry, Multidisciplinary

Nanoarchitectonics for Abused-Drug Biosensors

Rasoul Moradi et al.

Summary: Modern biosensor technologies are essential for detecting addictive and abused drugs, allowing accurate tracking and detection of trace levels of various drugs.

SMALL (2022)

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Editorial Material Biochemistry & Molecular Biology

Spotlight Seeing smell: the structural underpinnings of insect olfaction

Leisl Imani Brewster et al.

Summary: In a landmark paper, del Marmol et al. describe cryo-electron microscopy structures of an insect olfactory receptor ion channel, revealing the mechanism of how odorants directly gate ion flow. This study provides insights into the evolution of a highly diverse family of receptors supporting insects in navigating complex olfactory landscapes.

TRENDS IN BIOCHEMICAL SCIENCES (2022)

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Review Chemistry, Physical

The Synergistic Properties and Gas Sensing Performance of Functionalized Graphene-Based Sensors

Zandile Dennis Leve et al.

Summary: This article reviews the functionalization of graphene, synthesis of heterostructured nanohybrids, and the assessment of their collaborative performance towards gas-sensing applications.

MATERIALS (2022)

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Article Food Science & Technology

An Overview of Sensory Characterization Techniques: From Classical Descriptive Analysis to the Emergence of Novel Profiling Methods

Catarina Marques et al.

Summary: Sensory science provides objective information about consumer perception of products and the emotions they evoke. Discriminative and descriptive techniques can be used to understand how consumers perceive a product. Time-intensity methods can measure fluctuations in perception over time. Instrumental sensory devices and immersive techniques are becoming popular in sensory profiling. This paper reviews sensory techniques and highlights the importance of the timeline approach.

FOODS (2022)

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Article Biology

Odorant-binding proteins of mammals

Paolo Pelosi et al.

Summary: OBPs of vertebrates, specifically in mammals, are dedicated to pheromone communication by solubilizing, ferrying, and releasing pheromones. In contrast, insects' OBPs cater to general odorants in addition to pheromones. Mammals utilize a single family of carrier proteins for chemical communication, while insects and other arthropods possess multiple families of semiochemical-binding proteins.

BIOLOGICAL REVIEWS (2022)

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Review Nanoscience & Nanotechnology

Giant Magnetoresistance Biosensors in Biomedical Applications

Kai Wu et al.

Summary: The giant magnetoresistance (GMR) effect has been extensively developed and applied in various devices. This paper reviews the recent advances in GMR-based biomedical applications, including disease diagnosis, genotyping, and food and drug regulation. It also introduces the fundamental theories of the GMR effect and the emerging topic of flexible GMR for wearable biosensing. With the combination of complementary metal-oxide-semiconductor (CMOS) electronics, GMR biosensors hold great promise in biomedicine, particularly for point-of-care (POC) disease diagnosis and wearable devices for real-time health monitoring.

ACS APPLIED MATERIALS & INTERFACES (2022)

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Article Biochemistry & Molecular Biology

In Vivo Bioelectronic Nose Based on a Bioengineered Rat Realizes the Detection and Classification of Multiodorants

Ping Zhu et al.

Summary: This study developed an in vivo bioelectronic nose based on a bioengineered rat to detect specific odorants. By recording electrophysiological-responsive signals from the olfactory bulb, different odorants could be successfully classified and detected. The detection limit was low and the method showed promising application potential.

ACS CHEMICAL NEUROSCIENCE (2022)

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Article Biophysics

In-situ food spoilage monitoring using a wireless chemical receptor-conjugated graphene electronic nose

Kyung Ho Kim et al.

Summary: In this study, a high-performance chemical receptor-conjugated graphene electronic nose (CRGE-nose) was developed for in-situ monitoring of cadaverine (CV) and putrescine (PT) concentration changes in spoiled food.

BIOSENSORS & BIOELECTRONICS (2022)

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Article Environmental Sciences

Odor emissions: A public health concern for health risk perception

M. T. Piccardo et al.

Summary: Olfactory nuisance is primarily caused by improper waste disposal and animal farming. Long-term exposure to volatile compounds from these sources may pose risks for various diseases, including asthma, atopic dermatitis, and neurological damage.

ENVIRONMENTAL RESEARCH (2022)

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Article Biochemistry & Molecular Biology

The Porcine Odorant-Binding Protein as a Probe for an Impedenziometric-Based Detection of Benzene in the Environment

Alessandro Capo et al.

Summary: Odorant-binding proteins (OBPs) are small and soluble proteins that can bind to a wide range of odorant molecules. Benzene is a dangerous compound that requires sophisticated analytical techniques for detection. This study presents the use of an OBP isolated from pigs as a molecular recognition element in a low-energy biosensor for real-time benzene detection.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Review Chemistry, Analytical

Advanced wearable biosensors for the detection of body fluids and exhaled breath by graphene

Santoshi U. Singh et al.

Summary: Graphene is a trending material for developing wearable biosensors due to its outstanding physical, chemical, and structural properties. Wearable biosensors can non-invasively identify diseases by detecting relevant biomarkers in biofluids such as tears, sweat, interstitial fluid, saliva, and exhaled breath.

MICROCHIMICA ACTA (2022)

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Article Chemistry, Analytical

Olfactory receptor-based CNT-FET sensor for the detection of DMMP as a simulant of sarin

Jin Yoo et al.

Summary: DMMP, a simulant of sarin, is a representative of nerve agents that require sensitive detection for safety purposes. Utilizing human olfactory receptors on single-walled carbon nanotube-field effect transistors, the research focused on improving the sensitivity and selectivity of DMMP detection.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

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Article Chemistry, Analytical

Development of conductive molecularly imprinted polymers (cMIPs) for limonene to improve and interconnect QCM and chemiresistor sensing

Julia Voelkle et al.

Summary: This paper presents a straightforward method to develop a chemiresistor based sensor for the detection of the plant volatile R-(+)-limonene. By using blends of polystyrene-based molecularly imprinted polymers (MIPs) and the organic semiconductor poly3-hexylthiophene (P3HT), electrical conductivity is introduced into the highly selective MIPs, allowing their application as sensing layers in robust and economic chemiresistor devices. The presented results provide a simple and valuable way for potential MIP sensing improvements and the possibility for a method transfer to cheap and simple chemiresistors.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

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Article Chemistry, Analytical

Development and Assessment of Regeneration Methods for Peptide-Based QCM Biosensors in VOCs Analysis Applications

Tomasz Wasilewski et al.

Summary: Cleaning a quartz crystal microbalance (QCM) is crucial for regenerating biosensors. This article compares three methods (electrochemical, oxygen plasma, and Piranha solution) for cleaning QCM, and evaluates their effectiveness through resonant frequency measurements. The results show that all methods are suitable for cleaning peptide-based biosensors, but Piranha method is the most invasive.

BIOSENSORS-BASEL (2022)

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Article Biophysics

Design and optimization of E. coli artificial genetic circuits for detection of explosive composition 2,4-dinitrotoluene

Yan Zhang et al.

Summary: In this study, a whole-cell biosensor for detecting explosives was designed using synthetic biology tools, and its performance was optimized. The study lays the foundation for practical applications.

BIOSENSORS & BIOELECTRONICS (2022)

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Article Chemistry, Multidisciplinary

Bioelectrical Nose Platform Using Odorant-Binding Protein as a Molecular Transporter Mimicking Human Mucosa for Direct Gas Sensing

Danmin Choi et al.

Summary: A portable bioelectronic nose platform utilizing receptor protein and odorant-binding protein (OBP) was developed to detect insoluble gas odorants in a solution, mimicking the functionality of human mucosa. The platform demonstrated dose-dependent responses to octanal gas and showed improved sensor sensitivity compared to platforms without OBP. This bioelectronic nose platform allows direct detection of gas-phase odorant molecules and could have versatile applications and be useful for basic research.

ACS SENSORS (2022)

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Article Chemistry, Analytical

Ensemble Machine Learning Model for Accurate Air Pollution Detection Using Commercial Gas Sensors

Wei-In Lai et al.

Summary: This paper presents a study on commercial gas sensors and proposes an ensemble machine learning model for accurate concentration detection. By optimizing recurrent neural network models and integrating them using retraining, the detection accuracy and long-term stability have been significantly improved.

SENSORS (2022)

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Review Chemistry, Analytical

A review: Development and application of surface molecularly imprinted polymers toward amino acids, peptides, and proteins

Weidong Zhang et al.

Summary: Molecularly imprinted polymers (MIPs) have emerged as artificial antibodies with significant applications in the field of bioanalysis. Conventional bulk MIPs suffer from limitations such as low adsorption capacity, poor site accessibility, restricted mass transfer, and irregular morphology. Surface molecularly imprinted polymers (SMIPs) have garnered attention due to their large surface area, fast mass transfer, and high adsorption capacity and efficiency. This review provides a comprehensive summary of the preparation of SMIPs, including components and polymerization strategies, and discusses their applications in amino acids, peptides, and proteins. Furthermore, future trends and challenges in the design and development of SMIPs are described.

ANALYTICA CHIMICA ACTA (2022)

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Article Biophysics

Wireless portable bioelectronic nose device for multiplex monitoring toward food freshness/spoilage

Kyung Ho Kim et al.

Summary: In this study, a portable bioelectronic nose (BE-nose) integrated with trace amine-associated receptor (TAAR) nanodiscs (NDs) was developed for food quality monitoring. The BE-nose showed high sensitivity in detecting the biogenic amines cadaverine and putrescine in food samples. Additionally, by integrating commercial gas sensors, the accuracy and reliability of the BE-nose platform for real food samples were improved.

BIOSENSORS & BIOELECTRONICS (2022)

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Review Biochemistry & Molecular Biology

Template Imprinting Versus Porogen Imprinting of Small Molecules: A Review of Molecularly Imprinted Polymers in Gas Sensing

Todd Cowen et al.

Summary: Selective gas sensing is a challenge in analytical chemistry, and molecular imprinting is an effective method for achieving selectivity. This review discusses various methods and applications of molecularly imprinted polymers in gas sensors and vapor monitors, with a focus on sensitivity, selectivity, and challenges in imprinting small volatile compounds. The combination of porogen imprinting and template imprinting shows great potential in gas capture technology, but template imprinting is generally more suitable for selective and sensitive detection of gaseous molecules. Overall, gas-phase applications of MIPs are a well-established science capable of achieving high selectivity and parts-per-trillion sensitivity.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Review Chemistry, Inorganic & Nuclear

Metal oxide resistive sensors for carbon dioxide detection

Chao Zhang et al.

Summary: With the development of economy and society, the detection of carbon dioxide (CO2) has attracted more attention. Metal oxide semiconductor materials have been widely used in CO2 detection due to their various crystal structures, micro-nano morphologies, simple preparation process, and low cost. This article reviews the sensing mechanism and sensitization methods of CO2 gas sensing materials based on metal oxides, and introduces the CO2 sensing properties of chemical resistive sensors based on various metal oxide semiconductors, such as SnO2, ZnO, TiO2, and BaTiO3.

COORDINATION CHEMISTRY REVIEWS (2022)

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Review Biochemical Research Methods

Design and engineering of genetically encoded protein biosensors for small molecules

Alison C. Leonard et al.

Summary: This article reviews recent advances in genetically encoded protein biosensors for binding to novel ligands, categorizes sensor architecture as either integrated or portable, and proposes improvements for portable biosensor development, including standardizing protein scaffolds and automating ligand-compatibility screening and ligand-protein-interface design.

CURRENT OPINION IN BIOTECHNOLOGY (2022)

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Article Computer Science, Artificial Intelligence

Harvesting Context and Mining Emotions Related to Olfactory Cultural Heritage

M. Besher Massri et al.

Summary: This paper presents an Artificial Intelligence approach to mining context and emotions related to olfactory cultural heritage narratives, particularly in fairy tales. The study introduces a methodology for extracting smells and emotions from text and demonstrates the implementation of context-based visualizations. The evaluation using fairy tales shows successful detection of smells and emotions.

MULTIMODAL TECHNOLOGIES AND INTERACTION (2022)

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Article Chemistry, Multidisciplinary

Preparation of a quartz microbalance sensor based on molecularly imprinted polymers and its application in formaldehyde detection

Junbo Liu et al.

Summary: A molecularly imprinted quartz crystal microbalance (QCM) sensor was prepared and used for formaldehyde detection. The sensor exhibited good adsorption, selectivity, repeatability, high sensitivity, high accuracy, and a short response time. It can be used as a rapid detection method for formaldehyde content.

RSC ADVANCES (2022)

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Review Chemistry, Analytical

An Overview of Artificial Olfaction Systems with a Focus on Surface Plasmon Resonance for the Analysis of Volatile Organic Compounds

Marielle El Kazzy et al.

Summary: The increasing demand for novel analytical tools for gases over the last three decades has led to the development of alternative technologies like artificial olfaction systems. These systems, including gas sensors, olfactory biosensors, and electronic noses, utilize various transducers such as chemiresistive, electrochemical, acoustic, and optical. Among optical transduction systems, surface plasmon resonance (SPR) has been extensively studied and found to have attractive features such as high sensitivity, label-free, and real-time measurements.

BIOSENSORS-BASEL (2021)

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Article Chemistry, Analytical

Graphene Bioelectronic Nose for the Detection of Odorants with Human Olfactory Receptor 2AG1

Danielle M. Goodwin et al.

Summary: A real-time sensor utilizing a graphene resistor immobilized with OR2AG1 receptor for detecting amyl butyrate has been demonstrated. The sensor showed high sensitivity and selectivity towards the target odorant, with a linear sensor response between 0.1-500 pM and a sensitivity as low as 500 fM. The approach provides an alternative sensing platform for bioelectronic nose applications.

CHEMOSENSORS (2021)

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Article Biophysics

Biomimetic integrated olfactory sensory and olfactory bulb systems in vitro based on a chip

Keqiang Gao et al.

Summary: This paper constructs a biomimetic model to study the olfactory system, mapping olfactory associated ensembles of neuronal activity for understanding the physiological and pathological mechanisms of olfaction, as well as pharmacological applications in vitro.

BIOSENSORS & BIOELECTRONICS (2021)

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Review Biotechnology & Applied Microbiology

Insect odorant receptor-based biosensors: Current status and prospects

Jamal Ahmed Cheema et al.

Summary: The challenges of mimicking the sensitivity and accuracy of natural olfactory systems have prompted research into artificial olfactory devices using natural OR proteins. Research on using insect ORs as sensing elements is now being explored due to the insects' extraordinary sense of smell and their vital olfactory cues for survival. Despite challenges such as expression and purification, significant progress has been made in developing OR-based biosensors with insect ORs.

BIOTECHNOLOGY ADVANCES (2021)

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Review Immunology

Breath Biopsy and Discovery of Exclusive Volatile Organic Compounds for Diagnosis of Infectious Diseases

Jose E. Belizario et al.

Summary: Exhaled breath contains thousands of metabolites and volatile organic compounds that can serve as biomarkers for various human diseases. By studying VOC fingerprints generated by cellular and microbial metabolic pathways, potential biomarkers for disease diagnosis and classification can be identified.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

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Article Behavioral Sciences

Potential Therapeutic Targets for Olfactory Dysfunction in Ciliopathies Beyond Single-Gene Replacement

Chao Xie et al.

Summary: Olfactory dysfunction is a common disorder with various causes, including ciliopathies. Although there is currently no specific treatment for olfactory dysfunction caused by ciliopathies, targeted gene replacement shows promise as a potential therapeutic option. Further research is needed to develop alternative therapeutic targets for broader curative measures in ciliopathies.

CHEMICAL SENSES (2021)

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Review Biotechnology & Applied Microbiology

Biotechnological applications of mammalian odorant-binding proteins

Filipa Goncalves et al.

Summary: The mammalian olfactory system is able to detect and differentiate thousands of odors in the environment, thanks to the role of odorant-binding proteins (OBPs). OBPs have a strong ability to bind ligand molecules, with key parameters such as amino acids, temperature, ionic strength, and pH influencing the formation of OBP/ligand complexes. The information on OBP structure, affinity, binding strength, and stability from literature has inspired the development of various detailed applications.

CRITICAL REVIEWS IN BIOTECHNOLOGY (2021)

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Review Environmental Sciences

A review of environmental odor quantification and qualification methods: The question of objectivity in sensory analysis

Charbel Hawko et al.

Summary: This paper reviews the most commonly used sensory methodology for quantitative and qualitative environmental assessment of odor dimensions. It discusses assessment techniques for odor intensity, concentration, nature, and hedonic tone, comparing panel characteristics and discussing the objectivity of results in laboratory and field studies. The paper provides readers with a guide for environmental odor sensory analysis, allowing them to choose methods based on study nature, expectations, and capacities.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

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Article Chemistry, Analytical

Field-Effect Sensors Using Biomaterials for Chemical Sensing

Chunsheng Wu et al.

Summary: Biological chemical sensing systems, such as olfactory and taste systems, have evolved over millions of years to become highly powerful in detecting and discriminating various chemical substances. Developing field-effect sensors using biomaterials for chemical sensing has broad applications but is also challenging. Recent advances in this area have shown promising prospects and potential applications, although there are still limitations and challenges to address in the future.

SENSORS (2021)

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Article Chemistry, Analytical

Efficient fusion of spiking neural networks and FET-type gas sensors for a fast and reliable artificial olfactory system

Dongseok Kwon et al.

Summary: A new artificial olfactory system based on a spiking neural network (SNN) and field-effect transistor (FET)-type gas sensors was proposed for quickly and reliably detecting toxic gases. The system showed a low error rate in predicting the concentrations of NO2 and H2S, with real-time gas concentration prediction achieved within approximately 5 seconds. The hardware-based SNN outperformed conventional machine learning algorithms, showcasing its superiority in detecting toxic gases.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Analytical

Peptide-based electrochemical biosensing

Liang Yuan et al.

Summary: Peptides have shown great potential in a variety of applications, particularly in the field of nanotechnology where they are used as biomaterials for constructing new nanostructures. Peptide-based biosensors are being extensively studied and are expected to play a significant role in advanced biomolecular analyses.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Analytical

Elastic loading enhanced NH3 sensing for surface acoustic wave sensor with highly porous nitrogen doped diamond like carbon film

Hao Zhu et al.

Summary: The study introduced a SAW NH3 gas sensor based on NDLC film, characterized by high sensitivity, low noise, and excellent stability, capable of monitoring NH3 gas in a range from 100 ppb to 100 ppm.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Article Chemistry, Analytical

Insect odorant receptor nanodiscs for sensitive and specific electrochemical detection of odorant compounds

Jamal Ahmed Cheema et al.

Summary: This study presents an electrochemical sensing methodology using an insect odorant receptor (iOR) as the biological recognition element for detection of odorant compounds. The fruit fly Drosophila melanogaster's Or22a was used as a model receptor and shown to be functionally active towards its known ligand (ethyl hexanoate). The EIS sensor exhibited high sensitivity and specificity towards ethyl hexanoate with a detection limit of 5.5 fM, with neutron reflectometry studies providing evidence of conformational changes in the receptor upon ligand binding.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Review Oncology

Volatile Organic Compounds in Human Exhaled Breath to Diagnose Gastrointestinal Cancer: A Meta-Analysis

Lijuan Xiang et al.

Summary: Through systematic searches and meta-analysis of related studies, this article demonstrates the feasibility and potential of utilizing exhaled volatile organic compounds (VOCs) for diagnosing gastrointestinal cancers. The results show promising sensitivity and specificity of VOC analysis in diagnosing colorectal cancer (CRC) and gastroesophageal cancer (GEC), indicating that VOCs could serve as valuable tumor biomarkers for gastrointestinal cancer diagnosis.

FRONTIERS IN ONCOLOGY (2021)

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Article Biophysics

Binary mixture quantification using cell-based odor biosensor system with active sensing

Yuji Sukekawa et al.

Summary: This study focuses on quantifying odorant concentrations using a sensor array comprised of various cell-based odor sensors with insect olfactory receptors and an active sensing method. The study successfully determined relative concentrations even when response fluctuation was large or sensor cell responses varied with increasing measurement time, providing insight into the development of a new type of odor biosensor with active sensing.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Biophysics

Optical bioelectronic nose of outstanding sensitivity and selectivity toward volatile organic compounds implemented with genetically engineered bacteriophage: Integrated study of multi-scale computational prediction and experimental validation

Jungyun Park et al.

Summary: This paper demonstrates a highly selective and responsive optical biosensor using genetically engineered phages with optimized peptide sequences interacting with volatile organic compounds. The sensor shows significant improvement in sensing resolution and classification success rate for explosive VOCs, achieved through a systematic approach combining computational prediction and experimental validation.

BIOSENSORS & BIOELECTRONICS (2021)

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Article Biophysics

Investigation of colorimetric biosensor array based on programable surface chemistry of M13 bacteriophage towards artificial nose for volatile organic compound detection: From basic properties of the biosensor to practical application

Jong-Min Lee et al.

Summary: This study analyzed the correlation between surface chemistry of genetically engineered bacteriophages and the properties of bacteriophage-based optoelectronic noses, demonstrating controllable reactivity through genetic engineering. Phages advantageous in distinguishing VOCs were selected through HCA, with the differences verified through optimized geometry calculated by DFT. The study confirmed the importance of tryptophan-based and histidine-based genetically engineered phage films in distinguishing VOCs used to evaluate peach freshness, and applied this to design a field-applied phage-based optoelectronic nose for measuring fruit freshness.

BIOSENSORS & BIOELECTRONICS (2021)

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Review Chemistry, Analytical

Emerging strategies for enhancing detection of explosives by artificial olfaction

Tomasz Wasilewski et al.

Summary: Explosives detection systems rely on artificial olfaction technologies to detect a wide range of explosive materials and their vapours. The trend is towards improving sensors' fundamental metrological parameters to construct sensor arrays for detecting trace quantities of explosives. Progress in nanotechnology and mimicking biological sense of smell have expanded the boundaries of artificial olfaction technologies.

MICROCHEMICAL JOURNAL (2021)

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Article Multidisciplinary Sciences

RHINOS: A lightweight portable electronic nose for real-time odor quantification in wastewater treatment plants

Javier Burgues et al.

Summary: The study introduces a portable lightweight electronic nose for real-time odor monitoring in wastewater treatment plants, with accuracy close to dynamic olfactometry, suitable for identifying odor sources. After calibration and validation, promising results support its application in odor control and abatement.

ISCIENCE (2021)

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Review Biochemistry & Molecular Biology

Electrochemical Biosensors in Food Safety: Challenges and Perspectives

Antonella Curulli

Summary: Safety and quality are essential in the food industry, leading to a growing demand for sensitive sensing systems to protect against harmful substances. Electrochemical sensors/biosensors are important tools in food screening, although they still face challenges in their development and application.

MOLECULES (2021)

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Article Chemistry, Analytical

Biosensor array based on ligand binding proteins for narcotics and explosives detection

Emmanuel Scorsone et al.

Summary: The study utilized surface acoustic wave (SAW) transducers coated with nanodiamond to integrate different Ligand Binding Proteins (LBPs) for detecting explosives and illegal drugs with high sensitivity and selectivity. The affinity constant of 14 LBPs towards 19 chemical targets was initially evaluated in aqueous solution, with subsequent investigations in the vapor phase showing sensor capabilities for discriminating compounds.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Review Chemistry, Analytical

Bio-inspired approaches for explosives detection

Tomasz Wasilewski et al.

Summary: Animals' unique abilities in analyzing complex gas substances make them the gold standard in explosives analysis, and the unusual capabilities of biological chemosensory systems inspire the development of devices mimicking their activity. The electronic analogues are being extensively studied in various research centers, bringing commercialization closer and potentially replacing or complementing animals in gas substance analysis.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2021)

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Review Biochemistry & Molecular Biology

The 40-Year Mystery of Insect Odorant-Binding Proteins

Karen Rihani et al.

Summary: OBPs are a family of odorant-binding proteins that play a crucial role in chemoreception of insects. Apart from their function in transporting hydrophobic stimuli to chemoreceptors, OBPs also have roles in buffering odorant level changes and hygro-reception. The physiological roles of OBPs expressed in other body tissues remain to be investigated.

BIOMOLECULES (2021)

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Article Chemistry, Analytical

Market Perspectives and Future Fields of Application of Odor Detection Biosensors within the Biological Transformation-A Systematic Analysis

Johannes Full et al.

Summary: This paper comprehensively analyzes the technological advantages of biosensors over traditional technical sensors for odor detection, and identifies the specific market potentials of biosensors in various application fields. The study reveals that biosensor technology has high application potential, especially in health and safety applications, due to their ability to meet key performance criteria. Additionally, the paper discusses the role of biosensors in the biological transformation and explores new application scenarios for multi-sensing biosensors.

BIOSENSORS-BASEL (2021)

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Review Chemistry, Analytical

Advancing sensing technology with CRISPR: From the detection of nucleic acids to a broad range of analytes e A review

Siying Xie et al.

Summary: CRISPR/Cas technology, originating from bacteria's adaptive immune system, has been recognized by the Nobel Prize in Chemistry for its achievements in gene editing. It has a wide range of applications, including biosensors detection, with advantages such as high accuracy, specificity, rapid response, and integrity, attracting significant research interest. In addition to nucleic acid monitoring, CRISPR technology also shows promise in detecting various biomarkers, making it valuable to explore and summarize strategies for recognizing a broad range of targets.

ANALYTICA CHIMICA ACTA (2021)

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Article Biochemistry & Molecular Biology

Gene therapy rescues olfactory perception in a clinically relevant ciliopathy model of Bardet-Biedl syndrome

Chao Xie et al.

Summary: Bardet-Biedl syndrome (BBS) is a hereditary genetic disorder that leads to various clinical manifestations, including olfactory dysfunction. A study using a mouse model found that the olfactory system of Bbs1(M390R/M390R) mice was significantly affected, but their odor discrimination acuity was still well maintained. Adenoviral expression of Bbs1 in olfactory sensory neurons can restore olfactory system function.

FASEB JOURNAL (2021)

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Review Biochemistry & Molecular Biology

Electrochemical Peptide-Based Sensors for Foodborne Pathogens Detection

Mihaela Tertis et al.

Summary: Food safety and quality control are critical issues affecting consumers and public health, with unsafe food posing particular risks to certain populations. Peptide-based sensors have emerged as a promising alternative in food research, offering potential applications for rapid, non-destructive analysis of food samples and aiding in healthcare and economic systems strengthening.

MOLECULES (2021)

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Article Multidisciplinary Sciences

The structural basis of odorant recognition in insect olfactory receptors

Josefina del Marmol et al.

Summary: Olfactory systems use a common strategy of combinatorial activation of olfactory receptors to detect a vast chemical world. The olfactory receptor MhOR5 from the jumping bristletail is a homotetrameric odorant-gated ion channel with broad chemical tuning, recognizing odorants through distributed hydrophobic interactions in a simple binding pocket. The receptor's sensitivity to odorants can be predictably altered by mutating individual residues in the binding pocket, shedding light on the molecular recognition mechanisms of the olfactory system.

NATURE (2021)

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Review Chemistry, Analytical

Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors

Xiaofeng Zheng et al.

Summary: This review critically summarizes the recent advances in imprinted polymer-based electrochemical sensors, highlighting their applications in detecting pesticides, metal ions, and waterborne pathogenic bacteria with low cost, high selectivity, and sensitivity.

SENSORS (2021)

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Review Chemistry, Multidisciplinary

Tailored Biosensors for Drug Screening, Efficacy Assessment, and Toxicity Evaluation

Yi Tao et al.

Summary: Biosensors have shown significant developments in drug discovery, aiding in the screening and discovery of innovative drugs. This overview discusses recent progress in tailored biosensors, highlighting their mechanisms and applications in drug screening, efficacy assessment, and toxicity evaluation, as well as the incorporation of functional nanomaterials. Representative examples of different biosensor types are compared in terms of design strategy, response mechanism, and potential applications, demonstrating the challenges and prospects of biosensors-assisted drug discovery.

ACS SENSORS (2021)

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Review Engineering, Electrical & Electronic

Flexible Electrochemical Biosensors for Health Monitoring

Anneng Yang et al.

Summary: Flexible electrochemical biosensors are crucial in disease diagnosis and healthcare management, mainly used for detecting biomarkers in various body fluids. These sensors can be employed as wearable devices for in-situ detection and long-term monitoring of target analytes. Transistor-based flexible biosensors exhibit high sensitivity and low detection limits, suitable for multiplexing and high-throughput sensing applications.

ACS APPLIED ELECTRONIC MATERIALS (2021)

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Review Chemistry, Analytical

Sensing Food Contaminants: Advances in Analytical Methods and Techniques

Rebeca S. Rodriguez et al.

ANALYTICAL CHEMISTRY (2021)

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Review Cell Biology

Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors

Dieter Wicher et al.

Summary: The majority of insect olfactory receptors belong to two distinct protein families - ionotropic receptors (IRs) related to the ionotropic glutamate receptor family, and odorant receptors (ORs) evolved from the gustatory receptor family. Both types assemble into heteromeric ligand-gated cation channels, addressing environmental and ecological challenges insects face.

CELL AND TISSUE RESEARCH (2021)

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Review Materials Science, Multidisciplinary

Colorimetric Sensors for Toxic and Hazardous Gas Detection: A Review

Sung Hwan Cho et al.

Summary: With the rapid development of industries, the threat of toxic and hazardous substances to human health is increasing, leading to a rising demand for accurate sensors. Colorimetric sensors, which detect substances by measuring absorbance or fluorescence spectra shift, are one of the emerging strategies today. Practical applications of colorimetric sensors require detection of low concentrations of toxic and hazardous substances in gaseous media, along with considerations for low power consumption, selectivity, and sensitivity for Internet of Things (IoT) applications.

ELECTRONIC MATERIALS LETTERS (2021)

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Review Biochemical Research Methods

Expression and purification of recombinant G protein-coupled receptors: A review

Daniel N. Wiseman et al.

PROTEIN EXPRESSION AND PURIFICATION (2020)

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Review Biology

FET-based nanobiosensors for the detection of smell and taste

Dongseok Moon et al.

SCIENCE CHINA-LIFE SCIENCES (2020)

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Article Chemistry, Analytical

Development of an optoelectronic nose based on surface plasmon resonance imaging with peptide and hairpin DNA for sensing volatile organic compounds

Sara Gaggiotti et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

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Article Multidisciplinary Sciences

Modification of an Anopheles gambiae odorant binding protein to create an array of chemical sensors for detection of drugs

Khasim Cali et al.

SCIENTIFIC REPORTS (2020)

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Article Biophysics

A bioinspired peptide matrix for the detection of 2,4,6-trinitrotoluene (TNT)

Takumi Komikawa et al.

BIOSENSORS & BIOELECTRONICS (2020)

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Article Biophysics

Synergistic improvement in the performance of insect odorant receptor based biosensors in the presence of Orco

Roshan Khadka et al.

BIOSENSORS & BIOELECTRONICS (2020)

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Review Biochemistry & Molecular Biology

Peptide-protein based nanofibers in pharmaceutical and biomedical applications

Aysegul Yildiz et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Article Chemistry, Analytical

Highly sensitive and selective detection of human-derived volatile organic compounds based on odorant binding proteins functionalized silicon nanowire array

Anran Gao et al.

SENSORS AND ACTUATORS B-CHEMICAL (2020)

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Article Chemistry, Analytical

Improvement of sensitivity of surface plasmon resonance imaging for the gas-phase detection of volatile organic compounds

Sophie Brenet et al.

TALANTA (2020)

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Article Chemistry, Analytical

Determination of long-chain aldehydes using a novel quartz crystal microbalance sensor based on a biomimetic peptide

Tomasz Wasilewski et al.

MICROCHEMICAL JOURNAL (2020)

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Review Chemistry, Analytical

Peptides, DNA and MIPs in Gas Sensing. From the Realization of the Sensors to Sample Analysis

Sara Gaggiotti et al.

SENSORS (2020)

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Review Chemistry, Analytical

Microfluidics in Gas Sensing and Artificial Olfaction

Guilherme Rebordao et al.

SENSORS (2020)

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Article Biochemistry & Molecular Biology

Gene editing reveals obligate and modulatory components of the CO2 receptor complex in the malaria vector mosquito, Anopheles coluzzii

Feng Liu et al.

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY (2020)

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Article Oncology

Adding Rigor to Biomarker Evaluations-EDRN Experience

Ziding Feng et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2020)

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Review Biochemistry & Molecular Biology

Identification of key odorants in complex mixtures occurring in nature

Nicolas Baldovini et al.

NATURAL PRODUCT REPORTS (2020)

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Article Electrochemistry

Experimentally Designed Sensor for Direct Determination of the Environmentally Hazardous Compound and Occupational Exposure Biomarker (p-aminophenol) in Different Sampling Matrices

Ahmed S. Saad et al.

JOURNAL OF THE ELECTROCHEMICAL SOCIETY (2020)

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Article Business

Pleasant Ambient Scents: A Meta-Analysis of Customer Responses and Situational Contingencies

Holger Roschk et al.

JOURNAL OF MARKETING (2020)

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Review Chemistry, Analytical

The Emergence of Insect Odorant Receptor-Based Biosensors

Jonathan D. Bohbot et al.

BIOSENSORS-BASEL (2020)

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Review Multidisciplinary Sciences

Sharpening the Molecular Scissors: Advances in Gene-Editing Technology

Mike Broeders et al.

ISCIENCE (2020)

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Article Biophysics

Highly sensitive olfactory biosensors for the detection of volatile organic compounds by surface plasmon resonance imaging

Charlotte Hurot et al.

BIOSENSORS & BIOELECTRONICS (2019)

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Article Biophysics

Progress in the development of olfactory-based bioelectronic chemosensors

John W. Cave et al.

BIOSENSORS & BIOELECTRONICS (2019)

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Article Biophysics

Functional expression of olfactory receptors using cell-free expression system for biomimetic sensors towards odorant detection

Fangming Chen et al.

BIOSENSORS & BIOELECTRONICS (2019)

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Review Chemistry, Multidisciplinary

Molecularly Imprinted Polymers

Joseph J. BelBruno

CHEMICAL REVIEWS (2019)

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Article Biophysics

An ultrasensitive electrochemical impedance-based biosensor using insect odorant receptors to detect odorants

Roshan Khadka et al.

BIOSENSORS & BIOELECTRONICS (2019)

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Article Chemistry, Analytical

Investigating Electrochemical Stability and Reliability of Gold Electrode-electrolyte Systems to Develop Bioelectronic Nose Using Insect Olfactory Receptor

Roshan Khadka et al.

ELECTROANALYSIS (2019)

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Article Chemistry, Analytical

A selective chemiresistive sensor for the cancer-related volatile organic compound hexanal by using molecularly imprinted polymers and multiwalled carbon nanotubes

Sajjad Janfaza et al.

MICROCHIMICA ACTA (2019)

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Article Chemistry, Analytical

Odor Recognition with a Spiking Neural Network for Bioelectronic Nose

Ming Li et al.

SENSORS (2019)

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Article Chemistry, Multidisciplinary

Construction of a Biohybrid Odorant Sensor Using Biological Olfactory Receptors Embedded into Bilayer Lipid Membrane on a Chip

Nobuo Misawa et al.

ACS SENSORS (2019)

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Article Behavioral Sciences

Mammalian Taste Cells Express Functional Olfactory Receptors

Bilal Malik et al.

CHEMICAL SENSES (2019)

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Article Biochemical Research Methods

Cell-free expression, purification and characterization of Drosophila melanogaster odorant receptor OR42a and its co-receptor

Jianyong Li et al.

PROTEIN EXPRESSION AND PURIFICATION (2019)

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Article Multidisciplinary Sciences

Highly selective reduced graphene oxide (rGO) sensor based on a peptide aptamer receptor for detecting explosives

Kyungjae Lee et al.

SCIENTIFIC REPORTS (2019)

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Article Chemistry, Analytical

Ultrasensitive, Selective, and Highly Stable Bioelectronic Nose That Detects the Liquid and Gaseous Cadaverine

Jungkyun Oh et al.

ANALYTICAL CHEMISTRY (2019)

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Article Chemistry, Multidisciplinary

Peptide Screening from a Phage Display Library for Benzaldehyde Recognition

Masayoshi Tanaka et al.

CHEMISTRY LETTERS (2019)

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Article Engineering, Electrical & Electronic

Odor Discrimination Using Cell-Based Odor Biosensor System With Fluorescent Image Processing

Yuji Sukekawa et al.

IEEE SENSORS JOURNAL (2019)

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Review Oncology

Accuracy and Methodologic Challenges of Volatile Organic Compound-Based Exhaled Breath Tests for Cancer Diagnosis A Systematic Review and Meta-analysis

George B. Hanna et al.

JAMA ONCOLOGY (2019)

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Article Chemistry, Analytical

A Highly Selective Biosensor Based on Peptide Directly Derived from the HarmOBP7 Aldehyde Binding Site

Tomasz Wasilewski et al.

SENSORS (2019)

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Review Chemistry, Multidisciplinary

Conducting Nanomaterial Sensor Using Natural Receptors

Oh Seok Kwon et al.

CHEMICAL REVIEWS (2019)

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Article Nanoscience & Nanotechnology

Biosensing with Insect Odorant Receptor Nanodiscs and Carbon Nanotube Field-Effect Transistors

Thanihaichelvan Murugathas et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

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Article Chemistry, Analytical

Biosensors to Monitor Water Quality Utilizing Insect Odorant-Binding Proteins as Detector Elements

Spiros D. Dimitratos et al.

BIOSENSORS-BASEL (2019)

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Article Biophysics

In vivo bioelectronic nose using transgenic mice for specific odor detection

Keqiang Gao et al.

BIOSENSORS & BIOELECTRONICS (2018)

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Article Chemistry, Analytical

Applications and Advances in Bioelectronic Noses for Odour Sensing

Tran Thi Dung et al.

SENSORS (2018)

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Article Chemistry, Analytical

Highly Selective Rational Design of Peptide-Based Surface Plasmon Resonance Sensor for Direct Determination of 2,4,6-trinitrotoluene (TNT) Explosive

Jin Wang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Review Chemistry, Analytical

Surface modification and construction of LAPS towards biosensing applications

Jian Wang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Review Chemistry, Analytical

Advances in olfaction-inspired biomaterials applied to bioelectronic noses

Tomasz Wasilewski et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Article Chemistry, Analytical

Fine discrimination of volatile compounds by graphene-immobilized odorant-binding proteins

Caroline Kotlowski et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

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Article Multidisciplinary Sciences

Ensemble landmarking of 3D facial surface scans

Markus A. de Jong et al.

SCIENTIFIC REPORTS (2018)

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Article Multidisciplinary Sciences

The porcine odorant-binding protein as molecular probe for benzene detection

Alessandro Capo et al.

PLOS ONE (2018)

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Review Biotechnology & Applied Microbiology

Protein- and Peptide-Based Biosensors in Artificial Olfaction

Armenio J. M. Barbosa et al.

TRENDS IN BIOTECHNOLOGY (2018)

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Article Multidisciplinary Sciences

Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles

Jiao Zhu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

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Article Biochemical Research Methods

Biophysical and functional characterization of the human olfactory receptor OR1A1 expressed in a mammalian inducible cell line

Christine Belloir et al.

PROTEIN EXPRESSION AND PURIFICATION (2017)

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Article Chemistry, Analytical

A Formaldehyde Sensor Based on Molecularly-Imprinted Polymer on a TiO2 Nanotube Array

Xiaohui Tang et al.

SENSORS (2017)

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Article Chemistry, Analytical

Diamond micro-cantilevers as transducers for olfactory receptors - based biosensors: Application to the receptors M71 and OR7D4

R. Manai et al.

SENSORS AND ACTUATORS B-CHEMICAL (2017)

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Article Chemistry, Analytical

LSPR sensor array based on molecularly imprinted sol-gels for pattern recognition of volatile organic acids

Liang Shang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2017)

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Review Biotechnology & Applied Microbiology

Bioelectronic Nose: An Emerging Tool for Odor Standardization

Manki Son et al.

TRENDS IN BIOTECHNOLOGY (2017)

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Article Chemistry, Multidisciplinary

Nanodisc-Based Bioelectronic Nose Using Olfactory Receptor Produced in Escherichia coli for the Assessment of the Death-Associated Odor Cadaverine

Heehong Yang et al.

ACS NANO (2017)

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Article Chemistry, Physical

Liposomes and lipid bilayers in biosensors

Federico Mazur et al.

ADVANCES IN COLLOID AND INTERFACE SCIENCE (2017)

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Article Biophysics

Tailoring gas sensor arrays via the design of short peptides sequences as binding elements

Marcelo Mascini et al.

BIOSENSORS & BIOELECTRONICS (2017)

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Article Biophysics

A portable and multiplexed bioelectronic sensor using human olfactory and taste receptors

Manki Son et al.

BIOSENSORS & BIOELECTRONICS (2017)

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Review Biophysics

Bioelectronic nose: Current status and perspectives

Tomasz Wasilewski et al.

BIOSENSORS & BIOELECTRONICS (2017)

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Article Chemistry, Analytical

Bioelectronic Nose Using Odorant Binding Protein-Derived Peptide and Carbon Nanotube Field-Effect Transistor for the Assessment of Salmonella Contamination in Food

Manki Son et al.

ANALYTICAL CHEMISTRY (2016)

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Review Entomology

A look inside odorant-binding proteins in insect chemoreception

Nathalia F. Brito et al.

JOURNAL OF INSECT PHYSIOLOGY (2016)

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Review Biochemical Research Methods

Bioelectronic nose and its application to smell visualization

Hwi Jin Ko et al.

JOURNAL OF BIOLOGICAL ENGINEERING (2016)

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Article Biophysics

Cell-based microfluidic platform for mimicking human olfactory system

Seung Hwan Lee et al.

BIOSENSORS & BIOELECTRONICS (2015)

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Article Biophysics

Detection and classification of natural odors with an in vivo bioelectronic nose

Liujing Zhuang et al.

BIOSENSORS & BIOELECTRONICS (2015)

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Article Biophysics

Bioelectronic nose combined with a microfluidic system for the detection of gaseous trimethylamine

Seung Hwan Lee et al.

BIOSENSORS & BIOELECTRONICS (2015)

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Article Biophysics

Real-time monitoring of geosmin and 2-methylisoborneol, representative odor compounds in water pollution using bioelectronic nose with human-like performance

Manki Son et al.

BIOSENSORS & BIOELECTRONICS (2015)

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Article Chemistry, Multidisciplinary

An Ultrasensitive, Selective, Multiplexed Superbioelectronic Nose That Mimics the Human Sense of Smell

Oh Seok Kwon et al.

NANO LETTERS (2015)

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Article Chemistry, Analytical

A novel biomimetic olfactory cell-based biosensor with DNA-directed site-specific immobilization of cells on a microelectrode array

Liping Du et al.

SENSORS AND ACTUATORS B-CHEMICAL (2015)

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Article Chemistry, Analytical

Nanoplasmonic monitoring of odorants binding to olfactory proteins from honeybee as biosensor for chemical detection

Diming Zhang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2015)

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Article Multidisciplinary Sciences

Capacitance-modulated transistor detects odorant binding protein chiral interactions

Mohammad Yusuf Mulla et al.

NATURE COMMUNICATIONS (2015)

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Article Multidisciplinary Sciences

Single-carbon discrimination by selected peptides for individual detection of volatile organic compounds

Soomi Ju et al.

SCIENTIFIC REPORTS (2015)

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Review Biotechnology & Applied Microbiology

Structure and biotechnological applications of odorant-binding proteins

Paolo Pelosi et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)

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Article Biochemistry & Molecular Biology

Insights into structural features determining odorant affinities to honey bee odorant binding protein 14

Andreas Schwaighofer et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

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Review Chemistry, Multidisciplinary

Cell-Based Biosensors and Their Application in Biomedicine

Qingjun Liu et al.

CHEMICAL REVIEWS (2014)

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Article Neurosciences

In Vivo Identification of Eugenol-Responsive and Muscone-Responsive Mouse Odorant Receptors

Timothy S. McClintock et al.

JOURNAL OF NEUROSCIENCE (2014)

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Article Chemistry, Analytical

On 'Electronic Nose' methodology

Peter Boeker

SENSORS AND ACTUATORS B-CHEMICAL (2014)

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Article Biophysics

A peptide receptor-based bioelectronic nose for the real-time determination of seafood quality

Jong Hyun Lim et al.

BIOSENSORS & BIOELECTRONICS (2013)

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Article Chemistry, Analytical

DEVELOPMENT OF CELL-BASED OLFACTORY BIOSENSORS

Changjun Hou et al.

ANALYTICAL LETTERS (2012)

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Article Engineering, Biomedical

Mimicking the human smell sensing mechanism with an artificial nose platform

Sang Hun Lee et al.

BIOMATERIALS (2012)

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Article Biophysics

Nanovesicle-based bioelectronic nose platform mimicking human olfactory signal transduction

Hye Jun Jin et al.

BIOSENSORS & BIOELECTRONICS (2012)

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Article Engineering, Multidisciplinary

Microelectrode Recording of Tissue Neural Oscillations for a Bionic Olfactory Biosensor

Qingjun Liu et al.

JOURNAL OF BIONIC ENGINEERING (2012)

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Article Biotechnology & Applied Microbiology

Bioelectronic nose with high sensitivity and selectivity using chemically functionalized carbon nanotube combined with human olfactory receptor

Sang Hun Lee et al.

JOURNAL OF BIOTECHNOLOGY (2012)

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Article Chemistry, Multidisciplinary

Ultrasensitive Flexible Graphene Based Field-Effect Transistor (FET)-Type Bioelectronic Nose

Seon Joo Park et al.

NANO LETTERS (2012)

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Article Materials Science, Biomaterials

Olfactory receptor-based polypeptide sensor for acetic acid VOC detection

Suranjan Panigrahi et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2012)

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Review Chemistry, Analytical

Biology and applications of olfactory sensing system: A review

Sindhuja Sankaran et al.

SENSORS AND ACTUATORS B-CHEMICAL (2012)

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Article Chemistry, Multidisciplinary

Biomimetic Chemical Sensors Using Nanoelectronic Readout of Olfactory Receptor Proteins

Brett R. Goldsmith et al.

ACS NANO (2011)

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Review Biochemical Research Methods

Programming microbial population dynamics by engineered cell-cell communication

Hao Song et al.

BIOTECHNOLOGY JOURNAL (2011)

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Article Chemistry, Analytical

Olfactory receptor based piezoelectric biosensors for detection of alcohols related to food safety applications

Sindhuja Sankaran et al.

SENSORS AND ACTUATORS B-CHEMICAL (2011)

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Article Chemistry, Analytical

Olfactory mucosa tissue-based biosensor: A bioelectronic nose with receptor cells in intact olfactory epithelium

Qingjun Liu et al.

SENSORS AND ACTUATORS B-CHEMICAL (2010)

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Article Chemistry, Multidisciplinary

Polypyrrole Nanotubes Conjugated with Human Olfactory Receptors: High-Performance Transducers for FET-Type Bioelectronic Noses

Hyeonseok Yoon et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

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Article Chemistry, Multidisciplinary

Direct Cell Surface Modification with DNA for the Capture of Primary Cells and the Investigation of Myotube Formation on Defined Patterns

Sonny C. Hsiao et al.

LANGMUIR (2009)

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Review Chemistry, Multidisciplinary

Designing peptide based nanomaterials

Rein V. Ulijn et al.

CHEMICAL SOCIETY REVIEWS (2008)

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Article Multidisciplinary Sciences

Insect olfactory receptors are heteromeric ligand-gated ion channels

Koji Sato et al.

NATURE (2008)

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Article Chemistry, Analytical

Gold surface functionalization and patterning for specific immobilization of olfactory receptors carried by nanosomes

Jasmina Vidic et al.

ANALYTICAL CHEMISTRY (2007)

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Article Biochemical Research Methods

Functional analysis of a Drosophila melanogaster olfactory receptor expressed in Sf9 cells

Aidan Kiely et al.

JOURNAL OF NEUROSCIENCE METHODS (2007)

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Article Biochemical Research Methods

Self-assembled cellular microarrays patterned using DNA barcodes

Erik S. Douglas et al.

LAB ON A CHIP (2007)

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Article Biophysics

Olfactory cell-based biosensor: A first step towards a neurochip of bioelectronic nose

Qingjun Liu et al.

BIOSENSORS & BIOELECTRONICS (2006)

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Article Biotechnology & Applied Microbiology

Cell-based measurement of odorant molecules using surface plasmon resonance

Jin Young Lee et al.

ENZYME AND MICROBIAL TECHNOLOGY (2006)

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Article Biochemical Research Methods

Quantitative assessment of olfactory receptors activity in immobilized nanosomes: a novel concept for bioelectronic nose

Jasmina Minic Vidic et al.

LAB ON A CHIP (2006)

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Article Chemistry, Multidisciplinary

Study of Langmuir and Langmuir-Blodgett films of odorant-binding protein/amphiphile for odorant biosensors

YX Hou et al.

LANGMUIR (2005)

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Article Biophysics

Exploring the recognized bio-mimicry materials for gas sensing

TZ Wu et al.

BIOSENSORS & BIOELECTRONICS (2001)

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Article Chemistry, Analytical

From electronic to bioelectronic olfaction, or:: from artificial moses to real noses

W Göpel

SENSORS AND ACTUATORS B-CHEMICAL (2000)

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