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Review
Biochemistry & Molecular Biology
Primary Aldosteronism and Resistant Hypertension: A Pathophysiological Insight
Fabio Bioletto et al.
Summary: Primary aldosteronism is recognized as the most common cause of secondary hypertension, associated with high-risk phenotypes and increased cardiovascular morbidity. Excessive aldosterone secretion can contribute to the development of hypertension and drug resistance through various mechanisms and worsen end-organ damage.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Article
Endocrinology & Metabolism
Approach to the Patient on Antihypertensive Therapy: Screen for Primary Aldosteronism
Paolo Mulatero et al.
Summary: Primary aldosteronism is an overlooked condition with significant mortality and morbidity. The difficulty of screening patients on antihypertensive therapy has resulted in low testing rates. However, interference with medication may not always be necessary for accurate screening.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)
Article
Endocrinology & Metabolism
The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline
John W. Funder et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)