4.1 Letter

Letter in reply: indirect treatment comparison of anifrolumab efficacy versus belimumab in adults with systemic lupus erythematosus

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Anifrolumab efficacy and safety by type I interferon gene signature and clinical subgroups in patients with SLE: post hoc analysis of pooled data from two phase III trials

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Summary: This study characterizes the efficacy and safety of anifrolumab in patients with moderate-to-severe SLE. It shows that anifrolumab has consistent efficacy and safety across different subgroups of patients. However, the limited sample size in some subgroups limits the conclusions about treatment benefit with anifrolumab.

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Summary: Anifrolumab is more effective than belimumab in improving disease activity in patients with moderate-to-severe SLE.

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Trial of Anifrolumab in Active Systemic Lupus Erythematosus

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Assessing the performance of population adjustment methods for anchored indirect comparisons: A simulation study

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Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response

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