相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。In-depth characterization of phenolic profiling of Moraiolo extra-virgin olive oil extract and initial investigation of the inhibitory effect on Indoleamine-2,3-Dioxygenase (IDO1) enzyme
Federica Ianni et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2022)
The role of indoleamine 2,3-dioxygenase in allergic disorders
Seyed-Alireza Esmaeili et al.
MOLECULAR BIOLOGY REPORTS (2022)
Indoleamine 2,3-Dioxygenase-1 Expression is Changed During Bladder Cancer Cell Invasion
Hellen Joyce Sousa Pereira Santos et al.
INTERNATIONAL JOURNAL OF TRYPTOPHAN RESEARCH (2022)
Role of indoleamine 2,3-dioxygenase 1 (IDO1) and kynurenine pathway in the regulation of the aging process
Antero Salminen
AGEING RESEARCH REVIEWS (2022)
New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3-dioxygenase 1 (IDO1)
Jae Sik Yu et al.
ARCHIVES OF PHARMACAL RESEARCH (2022)
Indoleamine 2,3 Dioxygenase 1-The Potential Link between the Innate Immunity and the Ischemia-Reperfusion-Induced Acute Kidney Injury?
Anna Krupa et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses
Kunle Odunsi et al.
SCIENCE TRANSLATIONAL MEDICINE (2022)
Impact of IDO1 and IDO2 on the B Cell Immune Response
Lauren M. F. Merlo et al.
FRONTIERS IN IMMUNOLOGY (2022)
The Role of Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment
Xinting Huang et al.
CANCERS (2022)
Increased Indoleamine 2,3-Dioxygenase 1 (IDO-1) Activity and Inflammatory Responses during Chikungunya Virus Infection
Thiara Manuele Alves de Souza et al.
PATHOGENS (2022)
Indoleamine 2,3-Dioxygenase 1 Deletion-Mediated Kynurenine Insufficiency in Vascular Smooth Muscle Cells Exacerbates Arterial Calcification
Liu Ouyang et al.
CIRCULATION (2022)
Dual-target inhibitors of indoleamine 2, 3 dioxygenase 1 (Ido1): A promising direction in cancer immunotherapy
Ya Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
Marco Gargaro et al.
IMMUNITY (2022)
Eleven undescribed alkaloids from the rhizomes of Sinomenium acutum and their IDO1 and TDO inhibitory activities
Ran Bi et al.
PHYTOCHEMISTRY (2022)
The Kynurenine Pathway and Cancer: Why Keep It Simple When You Can Make It Complicated
Roumaissa Gouasmi et al.
CANCERS (2022)
Indoleamine 2, 3-Dioxygenase: A Professional Immunomodulator and Its Potential Functions in Immune Related Diseases
Fahimeh Heidari et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2022)
Recent advances of quinones as a privileged structure in drug discovery
Li Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Design, synthesis and biological evaluation of exiguamine A analogues as IDO1 inhibitors
Junmin Dong et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
The ups, downs and new trends of IDO1 inhibitors
Shulun Chen et al.
BIOORGANIC CHEMISTRY (2021)
Indoleamine and tryptophan 2,3-dioxygenases as important future therapeutic targets
Ana Dolsak et al.
PHARMACOLOGY & THERAPEUTICS (2021)
Tryptophan metabolism in brain tumors-IDO and beyond
Michael Platten et al.
CURRENT OPINION IN IMMUNOLOGY (2021)
Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
Wei Guo et al.
ACTA PHARMACOLOGICA SINICA (2020)
Discovery of 5-(pyridin-3-yl)-1H-indole-4,7-diones as indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
Kai-min Kong et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2020)
IDO activation, inflammation and musculoskeletal disease
Joy Ogbechi et al.
EXPERIMENTAL GERONTOLOGY (2020)
IDO and Kynurenine Metabolites in Peripheral and CNS Disorders
Yi-Shu Huang et al.
FRONTIERS IN IMMUNOLOGY (2020)
Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies
Lijie Zhai et al.
FRONTIERS IN IMMUNOLOGY (2020)
Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase 1 (HDAC1) Dual Inhibitors Derived from the Natural Product Saprorthoquinone
Yang Lin et al.
MOLECULES (2020)
Rational design, synthesis and biological evaluation of ubiquinone derivatives as IDO1 inhibitors
Yuyang Ding et al.
BIOORGANIC CHEMISTRY (2019)
Discovery of potent indoleamine 2,3-dioxygenase (IDO) inhibitor from alkaloids in Picrasma quassioides by virtual screening and in vitro evaluation
Ning Wang et al.
FITOTERAPIA (2019)
Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product
Hongchuan Zhao et al.
MOLECULES (2019)
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
Michael Platten et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
The interplay between cytokines and the Kynurenine pathway in inflammation and atherosclerosis
Roland Baumgartner et al.
CYTOKINE (2019)
Structural Basis of Inhibitor Selectivity in Human Indoleamine 2,3-Dioxygenase 1 and Tryptophan Dioxygenase
Khoa N. Pham et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Characterization and Nonenzymatic Transformation of Three Types of Alkaloids from Streptomyces albogriseolus MGR072 and Discovery of Inhibitors of Indoleamine 2,3-Dioxygenase
Du Gao et al.
ORGANIC LETTERS (2019)
Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target
Freek J. H. Sorgdrager et al.
FRONTIERS IN IMMUNOLOGY (2019)
Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity
Mincheol Kwon et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2019)
Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer
Francisco S. Barreto et al.
BEHAVIOURAL PHARMACOLOGY (2018)
Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1
Yan-Xiang Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Palladium(II)-Catalyzed Reaction of Lawsones and Propargyl Carbonates: Construction of 2,3-Furanonaphthoquinones and Evaluation as Potential Indoleamine 2,3-Dioxygenase Inhibitors
Xi Peng et al.
JOURNAL OF ORGANIC CHEMISTRY (2018)
Design, synthesis and structure-activity relationship study of novel naphthoindolizine and indolizinoquinoline-5,12-dione derivatives as IDO1 inhibitors
Rui Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Design, synthesis and biological evaluation of novel naphthoquinone derivatives as IDO1 inhibitors
Liangkun Pan et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Distinct roles of immunoreceptor tyrosine-based motifs in immunosuppressive indoleamine 2,3-dioxygenase 1
Elisa Albini et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2017)
Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health
Igor Cervenka et al.
SCIENCE (2017)
Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1
Ariel Lewis-Ballester et al.
NATURE COMMUNICATIONS (2017)
Tumor microenvironment and therapeutic response
Ting Wu et al.
CANCER LETTERS (2017)
Discovery of a Novel Scaffold as an Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Based on the Pyrrolopiperazinone Alkaloid, Longamide B
Zenyu Shiokawa et al.
CHEMMEDCHEM (2016)
IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
David H. Munn et al.
TRENDS IN IMMUNOLOGY (2016)
Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity
Christopher E. Blunt et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Tryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation
Qiongxin Wang et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2015)
Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway
Amy B. Dounay et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
The kynurenine pathway and neurodegenerative disease
Daniel C. Maddison et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2015)
Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1
Georgios Pantouris et al.
AMINO ACIDS (2014)
Antitumour agents as inhibitors of tryptophan 2,3-dioxygenase
Georgios Pantouris et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Mesenchymal Stem Cells Use IDO to Regulate Immunity in Tumor Microenvironment
Weifang Ling et al.
CANCER RESEARCH (2014)
Benzofuranquinones as inhibitors of indoleamine 2,3-dioxygenase (IDO). Synthesis and biological evaluation
Catarina Carvalho et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Indoleamine 2,3-Dioxygenase Inhibitors Isolated from the Sponge Xestospongia vansoesti: Structure Elucidation, Analogue Synthesis, and Biological Activity
Ryan M. Centko et al.
ORGANIC LETTERS (2014)
Indoleamine 2,3-dioxygenase inhibitory activity of derivatives of marine alkaloid tsitsikammamine A
Eduard Dolusic et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Aminophenoxazinones as Inhibitors of Indoleamine 2,3-Dioxygenase (IDO). Synthesis of Exfoliazone and Chandrananimycin A
Raffaele Pasceri et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Discovery of Tryptanthrin Derivatives as Potent Inhibitors of Indoleamine 2,3-Dioxygenase with Therapeutic Activity in Lewis Lung Cancer (LLC) Tumor-Bearing Mice
Shuangshuang Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Kynurenines in the CNS: recent advances and new questions
Laszlo Vecsei et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2
Supun M. Bakmiwewa et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2: The Absence of IDO1 Upregulates IDO2 Expression in the Epididymis
Masakazu Fukunaga et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2012)
Marine Natural Products and Other Derivatives as Potent Indoleamine 2,3-Dioxygenase Inhibitors
Evelyne Delfourne
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2012)
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR A novel IDO effector pathway targeted by D-1-methyl-tryptophan
Richard Metz et al.
ONCOIMMUNOLOGY (2012)
Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators
Eduard Dolusic et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: Pharmacophore modeling and molecular docking studies
Shalini John et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Oren-gedoku-to and its Constituents with Therapeutic Potential in Alzheimer's Disease Inhibit Indoleamine 2, 3-Dioxygenase Activity In Vitro
Cun-Jing Yu et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Plectosphaeroic Acids A, B, and C, Indoleamine 2,3-Dioxygenase Inhibitors Produced in Culture by a Marine Isolate of the Fungus Plectosphaerella cucumerina
Gavin Carr et al.
ORGANIC LETTERS (2009)
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?
Stefan Loeb et al.
NATURE REVIEWS CANCER (2009)
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors
Sanjeev Kumar et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Synthesis of indoleamine 2,3-dioxygenase inhibitory analogues of the sponge alkaloid exiguamine A
Gavin Carr et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease
Luigina Romani et al.
NATURE (2008)
Origin and physiological roles of inflammation
Ruslan Medzhitov
NATURE (2008)
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
Helen J. Ball et al.
GENE (2007)
Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific marine hydroid Garveia annulata
Alban Pereira et al.
JOURNAL OF NATURAL PRODUCTS (2006)
Crystal structure of human indoleamine 2,3-dioxygenase:: Catalytic mechanism of O2 incorporation by a heme-containing dioxygenase
H Sugimoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Monitoring tryptophan metabolism in chronic immune activation
K Schröcksnadel et al.
CLINICA CHIMICA ACTA (2006)
Structure-activity study of Brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors
P Gaspari et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism
O Takikawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
DH Munn et al.
IMMUNITY (2005)
Metabolism and function of coenzyme Q
M Turunen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2004)
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
C Uyttenhove et al.
NATURE MEDICINE (2003)