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Efficacy of traditional Chinese exercise for sarcopenia: A systematic review and meta-analysis of randomized controlled trials

期刊

FRONTIERS IN NEUROSCIENCE
卷 16, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fnins.2022.1094054

关键词

traditional Chinese exercise; traditional Chinese medicine; sarcopenia; systematic review; meta-analysis

资金

  1. National Natural Science Foundation of China
  2. Natural Science Foundation of Hainan Province
  3. Natural Science Foundation of Zhejiang Province
  4. Foundation of Health Commission of Hainan Province
  5. [82260978]
  6. [822RC689]
  7. [LGF22H270020]
  8. [21A200448]

向作者/读者索取更多资源

Traditional Chinese Exercise (TCE) shows clinical benefits in improving muscle strength and physical function for sarcopenia, with better results in chair stand test, squatting-to-standing test, gait speed, muscle strength, and no adverse events reported.
Objective: To conduct a systematic review and meta-analysis to evaluate the effectiveness of Traditional Chinese Exercise (TCE) for sarcopenia. Methods: A literature search was conducted in eight online databases from inception until September 2022. Based on the Cochrane risk of bias tool, randomized controlled trials (RCTs) with RoB score >= 4 were included for further analyses. The primary outcome was muscle strength and physical function, and the secondary outcomes were adverse events. Data collection and analyses were conducted by RevMan 5.4 Software. GRADE system was used to evaluate the certainty of evidence. Results: A total of 13 eligible RCTs with 718 subjects were identified and included in this study. Among them, 10 RCTs involved Yijinjing; 2 involved Tai Chi; and 1 involved Baduanjin. Meta-analyses showed that TCE had better clinical effects than control measures in the chair stand test (P < 0.00001, I-2 = 38%; Certainty of evidence: Moderate), squatting-to-standing test (P < 0.00001, I-2 = 0%; Certainty of evidence: Moderate), 6-m gait speed (P < 0.00001, I-2 = 13%; Certainty of evidence: Moderate), Time Up and Go Test (P = 0.03, I-2 = 81%; Certainty of evidence: Low), peak torque of the extensors (P = 0.03, I-2 = 0%; Certainty of evidence: Moderate), total work of the extensors (P = 0.03, I-2 = 35%; Certainty of evidence: Moderate), peak torque of the flexors (P = 0.03, I-2 = 47%; Certainty of evidence: Low), total work of the flexors (P = 0.02, I-2 = 42%; Certainty of evidence: Low), the average power of the flexors (P = 0.03, I-2 = 30%; Certainty of evidence: Moderate), and balance function (P < 0.00001, I-2 = 53%; Certainty of evidence: Low). In additional, no adverse events were reported in participants who receive TCE. Conclusion: The findings of the present systematic review, at least to a certain extent, provided supporting evidence for the routine use of TCE for sarcopenia.

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