4.5 Article

Regulation of Photosensitivity by the Hippo Pathway in Lupus Skin

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Rheumatology

Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway

Yu Du et al.

Summary: The study finds that VGLL3 can regulate the expression of type I interferon signature in fibroblast-like synoviocytes of rheumatoid arthritis patients, promoting the upregulation of interferon-stimulated genes. VGLL3 drives the IRF3-induced IFN-beta 1 expression by inhibiting the expression of WWTR1, thus promoting the type I interferon expression through autocrine IFN-beta 1 signaling.

ARTHRITIS RESEARCH & THERAPY (2022)

Review Oncology

WWC Proteins: Important Regulators of Hippo Signaling in Cancer

Verena Hoffken et al.

Summary: The conserved Hippo pathway plays a crucial role in regulating cell proliferation and apoptosis through various mechanisms, essential for organ size control and tumor prevention. WWC proteins, as components and upstream regulators of the Hippo pathway, are often overlooked in their role in cancer development.

CANCERS (2021)

Article Immunology

B Cell Signatures Distinguish Cutaneous Lupus Erythematosus Subtypes and the Presence of Systemic Disease Activity

Lisa Abernathy-Close et al.

Summary: Cutaneous lupus erythematosus (CLE) is a chronic inflammatory skin disease that commonly occurs in patients with systemic lupus erythematosus (SLE) and can also develop in the absence of systemic disease. Research has shown that skin-associated B cell responses distinguish CLE subtypes, with B cell function possibly being an important link between cutaneous lupus and systemic disease activity.

FRONTIERS IN IMMUNOLOGY (2021)

Article Medicine, General & Internal

Molecular Profiling of Cutaneous Lupus Lesions Identifies Subgroups Distinct from Clinical Phenotypes

Celine C. Berthier et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Biochemistry & Molecular Biology

Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces

Jutamas Uttagomol et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Medicine, Research & Experimental

The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity

Allison C. Billi et al.

JCI INSIGHT (2019)

Article Rheumatology

Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa

Mrinal K. Sarkar et al.

ANNALS OF THE RHEUMATIC DISEASES (2018)

Article Biochemistry & Molecular Biology

YAP and TAZ are essential for basal and squamous cell carcinoma initiation

Maud Debaugnies et al.

EMBO REPORTS (2018)

Review Biochemistry & Molecular Biology

Understanding the Molecular Genetics of Basal Cell Carcinoma

Cristina Pellegrini et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Dermatology

Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop

Jasmine N. Stannard et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)

Review Biochemistry & Molecular Biology

Regulation of the Hippo Pathway Transcription Factor TEAD

Kimberly C. Lin et al.

TRENDS IN BIOCHEMICAL SCIENCES (2017)

Article Developmental Biology

Integrin signalling regulates YAP and TAZ to control skin homeostasis

Ahmed Elbediwy et al.

DEVELOPMENT (2016)

Article Biochemistry & Molecular Biology

The role of cytokines in the pathogenesis of cutaneous lupus erythematosus

E. S. Robinson et al.

CYTOKINE (2015)

Article Multidisciplinary Sciences

Restriction of intestinal stem cell expansion and the regenerative response by YAP

Evan R. Barry et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

GENCODE: The reference human genome annotation for The ENCODE Project

Jennifer Harrow et al.

GENOME RESEARCH (2012)

Article Dermatology

Prevalence of self-report photosensitivity in cutaneous lupus erythematosus

Kristen Foering et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2012)

Article Biochemical Research Methods

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Cole Trapnell et al.

NATURE PROTOCOLS (2012)