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Jayasree S. Nair et al.
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Surojit Sur et al.
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Richard J. Youle et al.
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Peter Lenart et al.
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K Strebhardt et al.
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XQ Liu et al.
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Q Zhong et al.
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FoxM1 is required for execution of the mitotic programme and chromosome stability
J Laoukili et al.
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Polo-like kinases and oncogenesis
F Eckerdt et al.
ONCOGENE (2005)
Polo-like kinases (Plks) and cancer
N Takai et al.
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Tumor regression by combination antisense therapy against Plk1 and Bcl-2
R Elez et al.
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The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore
CS Stevenson et al.
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L Kneisel et al.
JOURNAL OF CUTANEOUS PATHOLOGY (2002)
Prognostic value of pololike kinase expression in melanomas
K Strebhardt et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)