相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。
Article
Biochemistry & Molecular Biology
Claudia Trejo-Soto et al.
Summary: This article provides insights into the general features of red blood cell membranes and their impact on blood flow and rheology. It covers the basic description of membranes and focuses on the characteristics and modeling of red blood cell membranes. It also reviews recent studies on the effect of the elastic properties of red blood cell membranes on blood flow and hemorheology, as well as specific hemorheological pathologies associated with the mechanical properties of red blood cells and their influence on microcirculation. The article concludes by discussing the potential of microfluidic applications for diagnosing and treating these diseases, thereby highlighting the importance of studying red blood cell membranes and their role in blood flow.
Article
Chemistry, Analytical
Claudia Trejo-Soto et al.
Summary: The rheological properties of blood, including viscosity and shear thinning behavior, are highly influenced by the concentration, membrane elasticity, and aggregation of its red blood cells. This study presents two methods for normalizing the viscosity of blood samples from different donors, based on erythrocyte concentration and shear rate. By introducing a non-dimensional coefficient that considers the response to shear rate, the proposed methodology can predict the health conditions of blood samples. Through these normalization methods, the differences between red blood cells in the samples can be determined, and a range can be defined for describing healthy blood samples with a single behavior.
Review
Chemistry, Analytical
Felicia Carotenuto et al.
Summary: The failure of tissues and organs due to degenerative diseases or trauma is a major concern globally. Tissue engineering offers a potential solution by regenerating or replacing damaged tissues and organs. Biomaterials play a crucial role in promoting new tissue formation, with their architectural features influencing cellular behaviors. Optimizing the micro/nano architecture of biomaterials is essential for successful regenerative therapy. Various micro/nanostructured biomaterials have been developed to mimic the structure of different soft and hard tissues, with a focus on muscle, cartilage, and bone tissue regeneration.
Article
Chemistry, Analytical
Claudio Durastanti et al.
Summary: This study utilizes Surface-Enhanced Raman Scattering (SERS) to investigate genomic DNA in aqueous droplets deposited onto silver-coated silicon nanowires, and demonstrates the ability to efficiently differentiate between spectra of tumoral and healthy cells. Two statistical approaches, based on Principal Components Analysis and l(2) distance computation, are developed and proven to be highly efficient. The synergy of SERS spectroscopy and statistical analysis enables rapid and cost-effective discrimination of healthy and tumoral genomic DNA, providing an alternative to complex and expensive DNA sequencing.
Article
Chemistry, Analytical
Salvatore Almaviva et al.
Summary: This work successfully detected and identified Bacillus thuringiensis (Bt) cells using surface-enhanced Raman spectroscopy (SERS), with a functionalized SERS chip to remove unwanted contaminants. Different chemometric approaches were applied to classify spectra accurately, with the last method being suitable for an automated recognition procedure.
Article
Materials Science, Biomaterials
Valentina Mussi et al.
Summary: This study utilized silver-coated silicon nanowires as a Raman spectroscopic platform to effectively distinguish healthy and cancer genomic DNA without false negative identifications and with minimal false positive results. The research revealed conformational and charge differences between healthy and cancer cell DNA, impacting the arrangement of molecules adsorbed onto the nanowires during water evaporation.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Review
Chemistry, Analytical
Salvatore Surdo et al.
Summary: This review discusses the physics and engineering strategies of photonic nanojets and their recent implementations for generating arbitrary nanopatterns. The potential impact of nanopatterning technologies based on photonic nanojets in various biomedical areas is also highlighted.
Article
Chemistry, Analytical
Valentina Mussi et al.
Summary: This study demonstrates the use of a novel Raman mapping approach to identify DNA bases at low concentrations and study their interactions with a nanostructured substrate. Results show a distinct interaction of guanine with the nanostructured surface, explaining the diverse behavior of DNA deposited on the same substrate and providing a new diagnostic method.
Article
Physiology
Lourdes Mendez-Mora et al.
Summary: This study aims to develop a hematocrit-independent method for detecting beta-thalassemia trait and iron deficiency anemia by rheological characterization of whole blood samples, forming the basis for developing a diagnosis and follow-up device. Viscosity is calculated by detecting the advancing fluid-air interface and a mathematical model is introduced to classify different blood conditions. The viscosity varies depending on various RBC factors and is compared to the gold-standard method for validation of clinical value.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Chemistry, Analytical
Arsalan Ul Haq et al.
Summary: Myocardial infarction is a serious consequence of coronary artery thrombosis, leading to ischemia and necrosis of the myocardium with poor innate regeneration capability. Traditional pharmacological and assistive device approaches have failed to meet the need for tissue regeneration post MI injuries. Nanotechnology and cardiac tissue engineering offer promising avenues for developing conductive constructs.
Review
Cell Biology
Felicia Carotenuto et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2020)
Article
Biochemical Research Methods
Valentina Gallo et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2020)
Review
Chemistry, Multidisciplinary
Sara Politi et al.
Article
Chemistry, Multidisciplinary
Salvatore Surdo et al.
Article
Chemistry, Physical
Salvatore Surdo et al.
APPLIED SURFACE SCIENCE
(2016)
Article
Biochemistry & Molecular Biology
Corrado Mandoli et al.
MACROMOLECULAR BIOSCIENCE
(2010)
