4.6 Editorial Material

Investigating the eukaryotic host-like SLiMs in microbial mimitopes and their potential as novel drug targets for treating autoimmune diseases

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Investigating the disordered regions (MoRFs, SLiMs and LCRs) and functions of mimicry proteins/peptides in silico

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Summary: Microbial mimicry of host proteins/peptides can lead to autoimmune diseases. This study revealed that many bacterial and viral host mimicry proteins have structural disorder, but only a few overlap with host's intrinsically disordered protein regions. Most pathogens mimic host proteins involved in ion binding and signaling pathways.

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