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Vincent F. Van Hee et al.
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Jessica B. McGillen et al.
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Ardeshir Kianercy et al.
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Christopher T. Hensley et al.
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Metabolic symbiosis in cancer: Refocusing the Warburg lens
Erica C. Nakajima et al.
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Kelly M. Kennedy et al.
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Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
Fabienne Guillaumond et al.
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Patrick S. Ward et al.
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Glutamine Deprivation Enhances Antitumor Activity of 3-Bromopyruvate through the Stabilization of Monocarboxylate Transporter-1
Simone Cardaci et al.
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The monocarboxylate transporter familyuRole and regulation
Andrew P. Halestrap et al.
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F. Invernizzi et al.
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Pierre Sonveaux et al.
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Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites
Melissa B. Pappalardi et al.
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Frederique Vegran et al.
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Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice
Tiago C. Leite et al.
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Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells
Sybille Mazurek
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2011)
Inhibition of tumor lactate oxidation: Consequences for the tumor microenvironment
Morten Busk et al.
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Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review
Paolo E. Porporato et al.
FRONTIERS IN PHARMACOLOGY (2011)
Ketones and lactate fuel tumor growth and metastasis Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli et al.
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HIF-1 and HIF-2 transcription factors - Similar but not identical
Agnieszka Loboda et al.
MOLECULES AND CELLS (2010)
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
Charles J. David et al.
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Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
R. J. DeBerardinis et al.
ONCOGENE (2010)
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Ping Gao et al.
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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
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Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Pierre Sonveaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
David R. Wise et al.
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Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Mark W. Dewhirst et al.
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Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
Ralph J. DeBerardinis et al.
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HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
Huafeng Zhang et al.
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Direct observation of individual endogenous protein complexes in situ by proximity ligation
Ola Soderberg et al.
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HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
I Papandreou et al.
CELL METABOLISM (2006)
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
HS Lu et al.
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Mxi1 is induced by hypoxia in a HIF-1-dependent manner and protects cells from c-Myc-induced apoptosis
PG Corn et al.
CANCER BIOLOGY & THERAPY (2005)
Pyruvate kinase type M2 and its role in tumor growth and spreading
S Mazurek et al.
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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
RJ Appelhoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology
S Walenta et al.
CURRENT MEDICINAL CHEMISTRY (2004)
Lactate: Mirror and motor of tumor malignancy
S Walenta et al.
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Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
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Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
HS Lu et al.
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Glucose catabolism in cancer cells - Identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions
SP Mathupala et al.
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