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Autofluorescence Image-Guided Endoscopy in the Management of Upper Aerodigestive Tract Tumors

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MDPI
DOI: 10.3390/ijerph20010159

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head and neck cancers; autofluorescence; narrow band imaging; surgical margins; endoscopy; upper aerodigestive tract tumor; oral cavity carcinoma; squamous cell carcinoma

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Autofluorescence and narrow-band imaging have reemerged in the medical field, thanks to advances in technology. These techniques, along with new optical instruments and fluorescence biomolecules, have improved the management of diseases, particularly upper aerodigestive tract tumors. Multispectral imaging and micro-endoscopy have further enhanced tumor management, allowing for early diagnosis and better treatment outcomes. Autofluorescence endoscopy is crucial for screening, diagnosing, and treating these tumors, as it can assess microtumoral deposits that are not visible with traditional endoscopy. Overall, this new technique has led to optimum management, improved treatment outcomes, and better prognosis for patients.
At this juncture, autofluorescence and narrow-band imaging have resurfaced in the medicine arena in parallel with current technology advancement. The emergence of newly developed optical instrumentation in addition to the discovery of new fluorescence biomolecules have contributed to a refined management of diseases and tumors, especially in the management of upper aerodigestive tract tumors. The advancement in multispectral imaging and micro-endoscopy has also escalated the trends further in the setting of the management of this tumor, in order to gain not only the best treatment outcomes but also facilitate early tumor diagnosis. This includes the usage of autofluorescence endoscopy for screening, diagnosis and treatment of this tumor. This is crucial, as microtumoral deposit at the periphery of the gross tumor can be only assessed via an enhanced endoscopy and even more precisely with autofluorescence endoscopic techniques. Overall, with this new technique, optimum management can be achieved for these patients. Hence, the treatment outcomes can be improved and patients are able to attain better prognosis and survival.

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