相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Trikafta Rescues CFTR and Lowers Monocyte P2X7R-induced Inflammasome Activation in Cystic Fibrosis
Claudie Gabillard-Lefort et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2022)
An interferon-inducible signature of airway disease from blood gene expression profiling
Jeong H. Yun et al.
EUROPEAN RESPIRATORY JOURNAL (2022)
Macrophage PD-1 associates with neutrophilia and re duce d bacterial killing in early cystic fibrosis airway disease
Camilla Margaroli et al.
JOURNAL OF CYSTIC FIBROSIS (2022)
Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis
Caterina Di Pietro et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2022)
Enhanced Proliferation of Ly6C+ Monocytes/Macrophages Contributes to Chronic Inflammation in Skin Wounds of Diabetic Mice
Jingbo Pang et al.
JOURNAL OF IMMUNOLOGY (2021)
Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease
Joschka Hey et al.
NATURE COMMUNICATIONS (2021)
Subacute TGFβ Exposure Drives Airway Hyperresponsiveness in Cystic Fibrosis Mice through the PI3K Pathway
Elizabeth L. Kramer et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)
Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis
Heledd H. Jarosz-Griffiths et al.
ELIFE (2020)
Single-Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis
Jonas C. Schupp et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)
Determinants of Resident Tissue Macrophage Identity and Function
Camille Bleriot et al.
IMMUNITY (2020)
Airway-Associated Macrophages in Homeostasis and Repair
Anna E. Engler et al.
CELL REPORTS (2020)
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
Miriam Merad et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Defining trained immunity and its role in health and disease
Mihai G. Netea et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Changes in Airway Microbiome and Inflammation with Ivacaftor Treatment in Patients with Cystic Fibrosis and the G551D Mutation
J. Kirk Harris et al.
ANNALS OF THE AMERICAN THORACIC SOCIETY (2020)
Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Svetoslav Chakarov et al.
SCIENCE (2019)
Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans
Lena J. Heung et al.
PLOS PATHOGENS (2019)
The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis
Tim Rosenow et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
Exploring the complex role of chemokines and chemoattractants in vivo on leukocyte dynamics
Bruna A. David et al.
IMMUNOLOGICAL REVIEWS (2019)
GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis
Yingze Zhang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)
GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance
Harding H. Luan et al.
CELL (2019)
Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele
P. G. Middleton et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
Joey Schyns et al.
NATURE COMMUNICATIONS (2019)
Elastase Exocytosis by Airway Neutrophils Is Associated with Early Lung Damage in Children with Cystic Fibrosis
Camilla Margaroli et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2019)
Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung
Kristopher R. Genschmer et al.
CELL (2019)
CCR2 mediates increased susceptibility to post-H1N1 bacterial pneumonia by limiting dendritic cell induction of IL-17
Stephen J. Gurczynski et al.
MUCOSAL IMMUNOLOGY (2019)
CFTR dysfunction increases endoglin and TGF-β signaling in airway epithelia
Teodora Nicola et al.
PHYSIOLOGICAL REPORTS (2019)
TGF beta as a therapeutic target in cystic fibrosis
Elizabeth L. Kramer et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2018)
Infection Is Not Required for Mucoinflammatory Lung Disease in CFTR-Knockout Ferrets
Bradley H. Rosen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)
Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model
Kun-Yu Teng et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Bacteria-driven peribronchial lymphoid neogenesis in bronchiectasis and cystic fibrosis
Justine Frija-Masson et al.
EUROPEAN RESPIRATORY JOURNAL (2017)
Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity
Sebastian A. Riquelme et al.
IMMUNITY (2017)
Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages
Catherine Sabatel et al.
IMMUNITY (2017)
The Cytokine TGF-β Promotes the Development and Homeostasis of Alveolar Macrophages
Xueyang Yu et al.
IMMUNITY (2017)
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span
Alexander V. Misharin et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Human Cystic Fibrosis Macrophages Have Defective Calcium-Dependent Protein Kinase C Activation of the NADPH Oxidase, an Effect Augmented by Burkholderia cenocepacia
Kaivon Assani et al.
JOURNAL OF IMMUNOLOGY (2017)
Cell Origin Dictates Programming of Resident versus Recruited Macrophages during Acute Lung Injury
Kara J. Mould et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2017)
Increased susceptibility of Cftr-/- mice to LPS-induced lung remodeling
Emanuela M. Bruscia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)
Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis
Kathryn A. Ramsey et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency
Claudio Sorio et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis
Katherine B. Hisert et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2016)
Innate and Adaptive Immunity in Cystic Fibrosis
Emanuela M. Bruscia et al.
CLINICS IN CHEST MEDICINE (2016)
Yolk Sac Macrophages, Fetal Liver, and Adult Monocytes Can Colonize an Empty Niche and Develop into Functional Tissue-Resident Macrophages
Lianne van de laar et al.
IMMUNITY (2016)
Macrophages in Tissue Repair, Regeneration, and Fibrosis
Thomas A. Wynn et al.
IMMUNITY (2016)
Alterations in blood leukocytes of G551D-bearing cystic fibrosis patients undergoing treatment with ivacaftor
Preston E. Bratcher et al.
JOURNAL OF CYSTIC FIBROSIS (2016)
Early pulmonary disease manifestations in cystic fibrosis mice
Rebecca J. Darrah et al.
JOURNAL OF CYSTIC FIBROSIS (2016)
Tissue biology perspective on macrophages
Yasutaka Okabe et al.
NATURE IMMUNOLOGY (2016)
Heart-resident CCR2+ macrophages promote neutrophil extravasation through TLR9/MyD88/CXCL5 signaling
Wenjun Li et al.
JCI INSIGHT (2016)
Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice
Benjamin Lee et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis
Luke W. Garratt et al.
EUROPEAN RESPIRATORY JOURNAL (2015)
Emphysema Is Common in Lungs of Cystic Fibrosis Lung Transplantation Patients: A Histopathological and Computed Tomography Study
Onno M. Mets et al.
PLOS ONE (2015)
Pulmonary macrophages: key players in the innate defence of the airways
Adam J. Byrne et al.
THORAX (2015)
Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation
Ping-xia Zhang et al.
NATURE COMMUNICATIONS (2015)
Novel Markers to Delineate Murine M1 and M2 Macrophages
Kyle A. Jablonski et al.
PLOS ONE (2015)
The heterogeneity of lung macrophages in the susceptibility to disease
Luisa Morales-Nebreda et al.
EUROPEAN RESPIRATORY REVIEW (2015)
Macrophage adaptation in airway inflammatory resolution
Manminder Kaur et al.
EUROPEAN RESPIRATORY REVIEW (2015)
Clinical Mechanism of the Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor in G551D-mediated Cystic Fibrosis
Steven M. Rowe et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
A randomized double blind, placebo controlled phase 2 trial of BIIL 284 BS (an LTB4 receptor antagonist) for the treatment of lung disease in children and adults with cystic fibrosis
M. W. Konstan et al.
JOURNAL OF CYSTIC FIBROSIS (2014)
Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung
Vanessa Espinosa et al.
PLOS PATHOGENS (2014)
Induction of Type I Interferon Signaling Determines the Relative Pathogenicity of Staphylococcus aureus Strains
Dane Parker et al.
PLOS PATHOGENS (2014)
Alveolar macrophages: plasticity in a tissue-specific context
Tracy Hussell et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung
Alexander V. Misharin et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)
MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation
M. S. Alexander et al.
CELL DEATH AND DIFFERENTIATION (2013)
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
Martin Guilliams et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Transforming Growth Factor β1 Genotypes in Relation to TGFβ1, Interleukin-8, and Tumor Necrosis Factor Alpha in Induced Sputum and Blood in Cystic Fibrosis
O. Eickmeier et al.
MEDIATORS OF INFLAMMATION (2013)
Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease
William T. Harris et al.
PLOS ONE (2013)
IP-10 Is a Potential Biomarker of Cystic Fibrosis Acute Pulmonary Exacerbations
George M. Solomon et al.
PLOS ONE (2013)
miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1
Christian Lacks Lino Cardenas et al.
PLOS GENETICS (2013)
PAI-1 in tissue fibrosis
Asish K. Ghosh et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2012)
Absence of the cystic fibrosis transmembrane regulator (Cftr) from myeloid-derived cells slows resolution of inflammation and infection
T. L. Bonfield et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2012)
Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis
Michael A. Gibbons et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis
Basant A. Abdulrahman et al.
AUTOPHAGY (2011)
Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis
Emanuela M. Bruscia et al.
JOURNAL OF IMMUNOLOGY (2011)
Dysfunctional CFTR Alters the Bactericidal Activity of Human Macrophages against Pseudomonas aeruginosa
Paola Del Porto et al.
PLOS ONE (2011)
Plasma TGF-β1 in Pediatric Cystic Fibrosis: Potential Biomarker of Lung Disease and Response to Therapy
William T. Harris et al.
PEDIATRIC PULMONOLOGY (2011)
Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling
Jason R. Rock et al.
DISEASE MODELS & MECHANISMS (2010)
Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis
Danjun Fang et al.
RESPIRATORY RESEARCH (2010)
Macrophages Directly Contribute to the Exaggerated Inflammatory Response in Cystic Fibrosis Transmembrane Conductance Regulator-/- Mice
Emanuela M. Bruscia et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)
Downregulation of MiR-199a Derepresses Hypoxia-Inducible Factor-1α and Sirtuin 1 and Recapitulates Hypoxia Preconditioning in Cardiac Myocytes
Shweta Rane et al.
CIRCULATION RESEARCH (2009)
Alveolar macrophages and CC chemokines are increased in children with cystic fibrosis
S. Brennan et al.
EUROPEAN RESPIRATORY JOURNAL (2009)
Monocyte chemoattractant chemokines in cystic fibrosis
Satish Rao et al.
JOURNAL OF CYSTIC FIBROSIS (2009)
Transforming Growth Factor-β1 in Bronchoalveolar Lavage Fluid From Children With Cystic Fibrosis
William T. Harris et al.
PEDIATRIC PULMONOLOGY (2009)
The spectrum of structural abnormalities on CT scans from patients with CF with severe advanced lung disease
M. Loeve et al.
THORAX (2009)
Generation of a Conditional Null Allele for Cftr in Mice
Craig A. Hodges et al.
GENESIS (2008)
CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
Anke Di et al.
NATURE CELL BIOLOGY (2006)
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
NV Serbina et al.
NATURE IMMUNOLOGY (2006)
High-resolution computed tomography imaging of airway disease in infants with cystic fibrosis
TM Martínez et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Genetic modifiers of lung disease in cystic fibrosis
ML Drumm et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Association of cystic fibrosis with abnormalities in fatty acid metabolism
SD Freedman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Mycobacterium tuberculosis in chemokine receptor 2-deficient mice:: Influence of dose on disease progression
HM Scott et al.
INFECTION AND IMMUNITY (2002)
Wasting as an independent predictor of mortality in patients with cystic fibrosis
R Sharma et al.
THORAX (2001)
Effect of Pseudomonas infection on weight loss, lung mechanics, and cytokines in mice
AM van Heeckeren et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)