相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients
Bastien Nguyen et al.
CELL (2022)
Transposable element regulation and expression in cancer
Erin E. Grundy et al.
FEBS JOURNAL (2022)
FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
Jia Z. Shen et al.
CELL (2021)
Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
Elizabeth A. Bowling et al.
CELL (2021)
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma
Lewis Au et al.
CANCER CELL (2021)
The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain
Saikat Bhattacharya et al.
NATURE COMMUNICATIONS (2021)
Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing
Saikat Bhattacharya et al.
NATURE COMMUNICATIONS (2021)
Prognostic Impact of Loss of SETD2 in Clear Cell Renal Cell Carcinoma
Victor Espinheira Santos et al.
CLINICAL GENITOURINARY CANCER (2021)
MDSC: Markers, development, states, and unaddressed complexity
Samarth Hegde et al.
IMMUNITY (2021)
Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
Sydney X. Lu et al.
CELL (2021)
Endogenous retroviruses in the origins and treatment of cancer
Natasha Jansz et al.
GENOME BIOLOGY (2021)
Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells
Ran Cheng et al.
ONCOGENE (2020)
SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12
Patricia Gonzalez-Rodriguez et al.
CELL DEATH & DISEASE (2020)
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
Huairui Yuan et al.
CANCER CELL (2020)
DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer
Aguirre A. de Cubas et al.
JCI INSIGHT (2020)
Genomic profiling in renal cell carcinoma
Nazli Dizman et al.
NATURE REVIEWS NEPHROLOGY (2020)
Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency
Parinaz Mehdipour et al.
NATURE (2020)
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
Hale Tunbak et al.
NATURE COMMUNICATIONS (2020)
Roles of SETD2 in LeukemiaTranscription, DNA-Damage, and Beyond
Anna Skucha et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma
Svenja Bihr et al.
NEOPLASIA (2019)
SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development
Qianhua Xu et al.
NATURE GENETICS (2019)
WashU Epigenome Browser update 2019
Daofeng Li et al.
NUCLEIC ACIDS RESEARCH (2019)
Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
Daehwan Kim et al.
NATURE BIOTECHNOLOGY (2019)
Epigenetic therapy in immune-oncology
Peter A. Jones et al.
NATURE REVIEWS CANCER (2019)
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal
Samra Turajlic et al.
CELL (2018)
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal
Samra Turajlic et al.
CELL (2018)
Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retroviruses
Hitoshi Ohtani et al.
GENOME RESEARCH (2018)
Integrative Epigenetic Analysis Reveals Therapeutic Targets to the DNA Methyltransferase Inhibitor Guadecitabine (SGI-110) in Hepatocellular Carcinoma
Minmin Liu et al.
HEPATOLOGY (2018)
Epigenetic modifiers: activities in renal cell carcinoma
Aguirre A. de Cubas et al.
NATURE REVIEWS UROLOGY (2018)
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Christopher J. Ricketts et al.
CELL REPORTS (2018)
ggsashimi: Sashimi plot revised for browser- and annotation-independent splicing visualization
Diego Garrido-Martin et al.
PLOS COMPUTATIONAL BIOLOGY (2018)
Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma
Christof C. Smith et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Endogenous retrovirus expression is associated with response to immune checkpoint blockade in clear cell renal cell carcinoma
Anshuman Panda et al.
JCI INSIGHT (2018)
Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi
Jean-Philippe Fortin et al.
BIOINFORMATICS (2017)
Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma
James J. Hsieh et al.
EUROPEAN UROLOGY (2017)
Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis
Huairui Yuan et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Intragenic DNA methylation prevents spurious transcription initiation
Francesco Neri et al.
NATURE (2017)
Strawberry: Fast and accurate genome-guided transcript reconstruction and quantification from RNA-Seq
Ruolin Liu et al.
PLOS COMPUTATIONAL BIOLOGY (2017)
Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma
Brandon John Manley et al.
EUROPEAN UROLOGY FOCUS (2017)
Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure
Gulfem Dilek Guler et al.
CANCER CELL (2017)
Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity
Kun Chen et al.
CELL (2017)
SETD2 histone modifier loss in aggressive GI stromal tumours
Kie Kyon Huang et al.
GUT (2016)
Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death
Thai H. Ho et al.
MODERN PATHOLOGY (2016)
High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma
T. H. Ho et al.
ONCOGENE (2016)
Dynamic reprogramming of DNA methylation in SETD2-deregulated renal cell carcinoma
Rochelle L. Tiedemann et al.
ONCOTARGET (2016)
Dual Chromatin and Cytoskeletal Remodeling by SETD2
In Young Park et al.
CELL (2016)
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
Raphael Bueno et al.
NATURE GENETICS (2016)
Targeting the cancer epigenome for therapy
Peter A. Jones et al.
NATURE REVIEWS GENETICS (2016)
deepTools2: a next generation web server for deep-sequencing data analysis
Fidel Ramirez et al.
NUCLEIC ACIDS RESEARCH (2016)
Vitamin C increases viral mimicry induced by 5-aza-2′-deoxycytidine
Minmin Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells
Christopher E. Duymich et al.
NATURE COMMUNICATIONS (2016)
Isoform switching and exon skipping induced by the DNA methylation inhibitor 5-Aza-2′-deoxycytidine
Xiao-Lei Ding et al.
SCIENTIFIC REPORTS (2016)
TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets
Ying Jin et al.
BIOINFORMATICS (2015)
DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
David Roulois et al.
CELL (2015)
Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
Katherine B. Chiappinelli et al.
CELL (2015)
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
Tuncay Baubec et al.
NATURE (2015)
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
Mihaela Pertea et al.
NATURE BIOTECHNOLOGY (2015)
miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma
Wei Xiang et al.
ONCOTARGET (2015)
PI3Kβ Inhibitor TGX221 Selectively Inhibits Renal Cell Carcinoma Cells with Both VHL and SETD2 mutations and Links Multiple Pathways
Chenchen Feng et al.
SCIENTIFIC REPORTS (2015)
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Yang Liao et al.
BIOINFORMATICS (2014)
Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
Xiaojing Yang et al.
CANCER CELL (2014)
Landmarks in the diagnosis and treatment of renal cell carcinoma
Jaimin R. Bhatt et al.
NATURE REVIEWS UROLOGY (2014)
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
Ophir Shalem et al.
SCIENCE (2014)
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint
Silvia Carvalho et al.
ELIFE (2014)
The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
Feng Li et al.
CELL (2013)
KDM4A Lysine Demethylase Induces Site-Specific Copy Gain and Rereplication of Regions Amplified in Tumors
Joshua C. Black et al.
CELL (2013)
Targeted Delivery of Paclitaxel to EphA2-Expressing Cancer Cells
Si Wang et al.
CLINICAL CANCER RESEARCH (2013)
Clinical and Pathologic Impact of Select Chromatin-modulating Tumor Suppressors in Clear Cell Renal Cell Carcinoma
A. Ari Hakimi et al.
EUROPEAN UROLOGY (2013)
DNA Methylation Screening Identifies Driver Epigenetic Events of Cancer Cell Survival
Daniel D. De Carvalho et al.
CANCER CELL (2012)
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons
Violaine Saint-Andre et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36
Sergio Fernandes de Almeida et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Differential patterns of intronic and exonic DNA regions with respect to RNA polymerase II occupancy, nucleosome density and H3K36me3 marking in fission yeast
Brian T. Wilhelm et al.
GENOME BIOLOGY (2011)
A decade of exploring the cancer epigenome - biological and translational implications
Stephen B. Baylin et al.
NATURE REVIEWS CANCER (2011)
BEDTools: a flexible suite of utilities for comparing genomic features
Aaron R. Quinlan et al.
BIOINFORMATICS (2010)
Regulation of Alternative Splicing by Histone Modifications
Reini F. Luco et al.
SCIENCE (2010)
The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters
W. Al Sarakbi et al.
BMC CANCER (2009)
Differential chromatin marking of introns and expressed exons by H3K36me3
Paulina Kolasinska-Zwierz et al.
NATURE GENETICS (2009)
Stromal transforming growth factor-β signaling mediates prostatic response to androgen ablation by paracrine Wnt activity
Veronica R. Placencio et al.
CANCER RESEARCH (2008)