4.8 Article

Hierarchical retinal computations rely on hybrid chemical-electrical signaling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Orientation and direction tuning align with dendritic morphology and spatial connectivity in mouse visual cortex

Simon Weiler et al.

Summary: In this study, the researchers found direct correlations between the dendritic morphology and functional input connectivity, as well as the orientation and direction tuning of L2/3 PCs. The elongation of the apical dendritic tree along the postsynaptic preferred orientation played an important role in the representation of visual space and the orientation tuning. Additionally, sharply orientation-tuned cells had a less complex apical tree compared to broadly tuned cells. The spatial distribution of presynaptic partners in direction-selective L2/3 PCs was offset from the soma opposite to the preferred direction, and the excitatory input distribution was spatially skewed along the preferred direction, in contrast to the inhibitory distribution.

CURRENT BIOLOGY (2022)

Article Cell Biology

Parallel processing in active dendrites during periods of intense spiking activity

Benjamin L. Murphy-Baum et al.

Summary: The ability of neurons to perform parallel computations in their dendritic arbor improves their computational capacity. Direction-selective ganglion cells in the mouse retina are able to compute the direction of moving objects multiple times as they traverse their receptive fields, allowing them to rapidly detect changes in motion direction. The parallel processing capacity of neurons can be maintained even during intense synaptic activity.

CELL REPORTS (2022)

Article Biology

Spatiotemporal properties of glutamate input support direction selectivity in the dendrites of retinal starburst amacrine cells

Prerna Srivastava et al.

Summary: In this study, the input kinetics across individual starburst dendrites were directly measured using a two-photon glutamate sensor. The study found that signals from proximal dendrites were relatively sustained, mainly influenced by excitatory network interactions. Computational modeling demonstrated the importance of input kinetics in shaping direction selectivity. These results provide support for the "space-time wiring" model.
Article Multidisciplinary Sciences

Classical center-surround receptive fields facilitate novel object detection in retinal bipolar cells

John A. Gaynes et al.

Summary: Antagonistic interactions between center and surround receptive field components are crucial in visual computations. We found that bipolar cells enhance responses to objects in their receptive field and show altered dynamics during continuous motion.

NATURE COMMUNICATIONS (2022)

Article Multidisciplinary Sciences

Center-surround interactions underlie bipolar cell motion sensitivity in the mouse retina

Sarah Strauss et al.

Summary: Motion sensing is a crucial aspect of vision. Research on mouse retinal bipolar cells has revealed the presence of radial direction selectivity, with some cells preferring the origin of small object motion trajectories. This selectivity relies on the properties of the center-surround receptive field. By studying these cells and using connectomics, biophysical models were developed to understand how their selectivity contributes to downstream cells. It was found that bipolar cells pass radial direction selective excitation to starburst amacrine cells, contributing to their directional tuning and potentially impacting motion processing throughout the visual system.

NATURE COMMUNICATIONS (2022)

Article Neurosciences

Nonlinear spatial integration in retinal bipolar cells shapes the encoding of artificial and natural stimuli

Helene Marianne Schreyer et al.

Summary: Research reveals that bipolar cells in the retina can serve as nonlinear processing elements, influencing the encoding of visual signals and providing sensitivity to spatial structures below their receptive fields. These nonlinearities seem to arise at the excitatory input stage of bipolar cells, suggesting a earlier start of nonlinear signal pooling than previously thought.

NEURON (2021)

Article Neurosciences

Direction selectivity in retinal bipolar cell axon terminals

Akihiro Matsumoto et al.

Summary: Through two-photon glutamate imaging, it was discovered that direction selectivity arises early at bipolar cell outputs, with individual bipolar cells containing distinct populations of axon terminal boutons with different preferred directions. Tuning at these boutons relies on cholinergic excitation and GABAergic inhibition, contributing to the incremental refinement of directional tuning in the excitatory visual pathway.

NEURON (2021)

Article Neurosciences

Mouse Retinal Cell Atlas: Molecular Identification of over Sixty Amacrine Cell Types

Wenjun Yan et al.

JOURNAL OF NEUROSCIENCE (2020)

Review Pharmacology & Pharmacy

Dopaminergic modulation of retinal processing from starlight to sunlight

Suva Roy et al.

JOURNAL OF PHARMACOLOGICAL SCIENCES (2019)

Article Neurosciences

Cholinergic excitation complements glutamate in coding visual information in retinal ganglion cells

Santhosh Sethuramanujam et al.

JOURNAL OF PHYSIOLOGY-LONDON (2018)

Review Neurosciences

Orientation-Selective Retinal Circuits in Vertebrates

Paride Antinucci et al.

FRONTIERS IN NEURAL CIRCUITS (2018)

Article Neurosciences

Heterocellular Coupling Between Amacrine Cells and Ganglion Cells

Robert E. Marc et al.

FRONTIERS IN NEURAL CIRCUITS (2018)

Article Multidisciplinary Sciences

A retinal code for motion along the gravitational and body axes

Shai Sabbah et al.

NATURE (2017)

Article Multidisciplinary Sciences

Inhibition decorrelates visual feature representations in the inner retina

Katrin Franke et al.

NATURE (2017)

Article Multidisciplinary Sciences

Electrical synapses convey orientation selectivity in the mouse retina

Amurta Nath et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics

Karthik Shekhar et al.

Article Neurosciences

Synaptic Mechanisms Generating Orientation Selectivity in the ON Pathway of the Rabbit Retina

Sowmya Venkataramani et al.

JOURNAL OF NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

The functional diversity of retinal ganglion cells in the mouse

Tom Baden et al.

NATURE (2016)

Article Multidisciplinary Sciences

Species-specific wiring for direction selectivity in the mammalian retina

Huayu Ding et al.

NATURE (2016)

Article Neurosciences

Morphology and connectivity of the small bistratified A8 amacrine cell in the mouse retina

Sammy C. S. Lee et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2015)

Article Neurosciences

Orientation Selectivity Sharpens Motion Detection in Drosophila

Yvette E. Fisher et al.

NEURON (2015)

Article Neurosciences

Functional Circuitry of the Retina

Jonathan B. Demb et al.

ANNUAL REVIEW OF VISION SCIENCE, VOL 1 (2015)

Article Biochemistry & Molecular Biology

Type II Cadherins Guide Assembly of a Direction-Selective Retinal Circuit

Xin Duan et al.

Article Neurosciences

Roles of ON Cone Bipolar Cell Subtypes in Temporal Coding in the Mouse Retina

Tomomi Ichinose et al.

JOURNAL OF NEUROSCIENCE (2014)

Review Neurosciences

Retinal bipolar cells: elementary building blocks of vision

Thomas Euler et al.

NATURE REVIEWS NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Spikes in Mammalian Bipolar Cells Support Temporal Layering of the Inner Retina

Tom Baden et al.

CURRENT BIOLOGY (2013)

Article Neurosciences

Orientation-selective Responses in the Mouse Lateral Geniculate Nucleus

Xinyu Zhao et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Connectomic reconstruction of the inner plexiform layer in the mouse retina

Moritz Helmstaedter et al.

NATURE (2013)

Review Neurosciences

Direction selectivity in the retina: symmetry and asymmetry in structure and function

David I. Vaney et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Article Neurosciences

Active Roles of Electrically Coupled Bipolar Cell Network in the Adult Retina

Itaru Arai et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Neurosciences

Orientation Selectivity in Rabbit Retinal Ganglion Cells Is Mediated by Presynaptic Inhibition

Sowmya Venkataramani et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Neurosciences

Receptive Fields of Retinal Bipolar Cells Are Mediated by Heterogeneous Synaptic Circuitry

Ai-Jun Zhang et al.

JOURNAL OF NEUROSCIENCE (2009)

Article Neurosciences

Cone Contacts, Mosaics, and Territories of Bipolar Cells in the Mouse Retina

Heinz Waessle et al.

JOURNAL OF NEUROSCIENCE (2009)

Article Neurosciences

Approach sensitivity in the retina processed by a multifunctional neural circuit

Thomas A. Muench et al.

NATURE NEUROSCIENCE (2009)

Review Neurosciences

The diverse functional roles and regulation of neuronal gap junctions in the retina

Stewart A. Bloomfield et al.

NATURE REVIEWS NEUROSCIENCE (2009)

Article Neurosciences

Receptive field properties of ON- and OFF-ganglion cells in the mouse retina

Michiel Van Wyk et al.

VISUAL NEUROSCIENCE (2009)

Article Multidisciplinary Sciences

Molecular identification of a retinal cell type that responds to upward motion

In-Jung Kim et al.

NATURE (2008)

Article Neurosciences

Presynaptic inhibition differentially shapes transmission in distinct circuits in the mouse retina

Erika D. Eggers et al.

JOURNAL OF PHYSIOLOGY-LONDON (2007)

Article Neurosciences

Populations of wide-field amacrine cells in the mouse retina

Bin Lin et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2006)

Article Neurosciences

Origin of transient and sustained responses in ganglion cells of the retina

GB Awatramani et al.

JOURNAL OF NEUROSCIENCE (2000)