期刊
BMJ OPEN
卷 12, 期 12, 页码 -出版社
BMJ PUBLISHING GROUP
DOI: 10.1136/bmjopen-2022-067621
关键词
Depression & mood disorders; Anxiety disorders; Protocols & guidelines
资金
- National Natural Science Foundation of China [81774249]
This study aims to summarize the evidence and evaluate the methodological quality regarding the effectiveness and safety of non-steroidal anti-inflammatory drugs (NSAIDs) for anxious depression.
IntroductionThere have been several studies showing the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) for anxious depression. We aimed to summarise the evidence and evaluate the methodological quality regarding the effectiveness and safety of NSAIDs for anxious depression from systematic reviews/meta-analyses (SRs/MAs). Methods and analysisTwo researchers searched seven databases for SRs/MAs, which are randomised controlled trials on NSAIDs for anxious depression. Two investigators used the Assessment System for Evaluating Methodological Quality 2, the Risk of Bias in Systematic reviews tool, the list of preferred reporting items for SRs/MAs and the Grading of Recommendations, Assessment, Development and Evaluation system to assess the included SRs/MAs. Ethics and disseminationThe findings of the study will be disseminated through peer-reviewed journals, and national and international conference presentations.
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