期刊
BMC PULMONARY MEDICINE
卷 22, 期 1, 页码 -出版社
BMC
DOI: 10.1186/s12890-022-02203-8
关键词
Rhinitis; Chronic bronchitis; Epidemiology
资金
- University of Gothenburg
- Swedish Research Council for Health
- Swedish Research Council for Health, Working Life and Welfare
- ALF Agreement relating
- Gothenburg Medical Society
This prospective study found an association between chronic rhinosinusitis (CRS) and chronic bronchitis (CB). The study revealed that individuals who reported CRS had a significantly increased risk of developing CB after five years. It is important for physicians to be aware of the potential presence of chronic bronchitis in patients with CRS.
Background Chronic rhinosinusitis (CRS) is associated with generalised airway inflammation. Few studies have addressed the relationship between CRS and chronic bronchitis (CB). Methods This prospective study over a five-year period aims to investigate the risk of developing CB in subjects reporting CRS at the beginning of the study. A random sample of 7393 adult subjects from Telemark County, Norway, answered a comprehensive respiratory questionnaire in 2013 and then 5 years later in 2018. Subjects reporting CB in 2013 were excluded from the analyses. New cases of CB in 2018 were analysed in relation to having CRS in 2013 or not. Results The prevalence of new-onset CB in 2018 in the group that reported CRS in 2013 was 11.8%. There was a significant increase in the odds of having CB in 2018 in subjects who reported CRS in 2013 (OR 3.8, 95% CI 2.65-5.40), adjusted for age, sex, BMI, smoking and asthma. Conclusion In this large population sample, CRS was associated with increased odds of developing CB during a five-year follow-up. Physicians should be aware of chronic bronchitis in patients with CRS.
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