Effects of coiling embolism on blood hemodynamic of the MCA aneurysm: a numerical study

Article Computer Science, Interdisciplinary Applications

Computational analysis of the blood hemodynamic inside internal cerebral aneurysm in the existence of endovascular coiling

Asal Sadeh et al.

Summary: Blood hematocrit, porosity, and blood viscosity have significant impacts on the risk of aneurysm rupture, and computational fluid dynamic simulations are reliable tools for recognizing high-risk regions and assessing aneurysm status.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C (2023)

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Article Computer Science, Interdisciplinary Applications

Application of computational fluid dynamics for detection of high risk region in middle cerebral artery (MCA) aneurysm

Ali Rostamian et al.

Summary: This paper conducts numerical studies to investigate the hemodynamic effects on the rupture of the middle cerebral artery (MCA) under different working conditions. The findings show that the increase in blood viscosity and velocity leads to higher wall shear stress and increases the risk of aneurysm rupture. The flow pattern inside the aneurysm and the angle of the incoming bloodstream also play important roles in the formation of high-risk regions.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C (2023)

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Article Multidisciplinary Sciences

Turning chiral peptides into a racemic supraparticle to induce the self-degradation of MDM2

Wenguang Yang et al.

Summary: A mild and simple self-assembly strategy was developed for the construction of peptide-derived chiral supramolecular nanomedicine with suitable pharmaceutical properties. The study demonstrated the potential of chiral supramolecular nanomedicine in suppressing tumor progression and enhancing tumor immunotherapy.

JOURNAL OF ADVANCED RESEARCH (2023)

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Article Computer Science, Interdisciplinary Applications

Configuration optimization of a renewable hybrid system including biogas generator, photovoltaic panel and wind turbine: Particle swarm optimization and genetic algorithms

Ali Heydari et al.

Summary: The main contribution of this paper is to formulate the problem of optimal design for a renewable wind/solar/biomass hybrid system in Iran and compare the performance of genetic algorithm (GA) and particle swarm optimization (PSO) on this problem. The research on solar and wind hybrid energy systems is abundant, but research on solar/wind/biomass hybrid energy systems is rare. The study finds that the biomass/PV system is the most cost-effective for supplying the required load, and PSO outperforms GA in terms of results.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C (2023)

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Article Engineering, Multidisciplinary

CFD investigations of the blood hemodynamic inside internal cerebral aneurysm (ICA) in the existence of coiling embolism

Zan -Hui Jin et al.

Summary: The coiling technique is the most significant and conventional option for treating an intracranial aneurysm. The effects of blood hemodynamics on the risk of aneurysm rupture are investigated through transient simulations of blood stream. The impacts of blood viscosity and coiling treatment on the distribution of WSS and OSI factors are comprehensively discussed.

ALEXANDRIA ENGINEERING JOURNAL (2023)

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Article Computer Science, Interdisciplinary Applications

Numerical simulation of blood flow effects on rupture of aneurysm in middle cerebral artery

Xiao-Yong Shen et al.

Summary: This research used computational fluid dynamics to investigate the rupture and growth of intracranial aneurysms in the middle cerebral artery. The study revealed the significant influence of blood viscosity and velocity on the danger of aneurysm rupture, with outcomes showing the direct impact of aneurysm location and orientation on its growth.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C (2022)

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Article Computer Science, Interdisciplinary Applications

Numerical study of droplet breakup in an asymmetric T-junction microchannel with different cross-section ratios

Milad Isanejad et al.

Summary: In this study, numerical simulations are performed to investigate droplet breakup in an asymmetric T-junction microchannel. The results show good agreement with previous studies, and the effects of capillary number, non-dimensional droplet length, and non-dimensional width ratio on the breakup time and splitting ratio are studied. It is also found that the mass center of the mother droplet is shifted to a wider branch, facilitating the asymmetric breakup in the T-junction microchannel.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C (2022)

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Article Chemistry, Analytical

Sb-doped WO3 based QCM humidity sensor with self-recovery ability for real-time monitoring of respiration and wound

Zhijia Li et al.

Summary: Humidity sensing is a promising method for monitoring respiration and diagnosing diseases. In this study, a humidity sensor using Sb-doped WO3 nanocrystals was successfully fabricated. The sensor exhibited fast response and recovery times, high sensitivity, and good stability and self-recovery ability under wet conditions. It was also applied to monitor moisture changes of a wound, which was previously unexplored using this type of sensor.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

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Article Multidisciplinary Sciences

Splitting of droplet with different sizes inside a symmetric T-junction microchannel using an electric field

Keivan Fallah et al.

Summary: In this study, droplets dynamics under an asymmetric electric field in a T-junction were numerically investigated, and two novel droplet patterns were observed. It was concluded that using an electric field allows for precise control over droplet size and splitting ratio.

SCIENTIFIC REPORTS (2022)

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Article Chemistry, Multidisciplinary

Serum Metal Ion-Induced Cross-Linking of Photoelectrochemical Peptides and Circulating Proteins for Evaluating Cardiac Ischemia/Reperfusion

Panpan Hao et al.

Summary: Patients who have experienced the ischemia-reperfusion process are at a higher risk of subsequent heart attacks. A novel assay using synthetic small molecules for detecting free copper ions and cathepsin G in serum has shown potential for evaluating the severity and prognosis of cardiac ischemia/reperfusion.

ACS SENSORS (2022)

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Article Multidisciplinary Sciences

Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study

Armin Sheidani et al.

Summary: This study comprehensively investigates the effects of blood hemodynamics on the creation and growth of internal carotid artery aneurysms using computational fluid dynamics. The study compares OSI and WSS of the aneurysm wall at different blood flow stages and explores the impact of blood viscosity and coiling treatment on these factors.

SCIENTIFIC REPORTS (2022)

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Article Environmental Sciences

Electrochemical degradation of antibiotic enoxacin using a novel PbO2 electrode with a graphene nanoplatelets inter-layer: Characteristics, efficiency and mechanism

Jingsong Dai et al.

Summary: In this study, a novel PbO2 electrode was fabricated by adding graphene nanoplatelets (GNP) inter-layer and utilized for degradation of antibiotic enoxacin. The experimental results showed that the electrode had a rough surface, smaller crystal size, and lower charge-transfer resistance, which could effectively inhibit oxygen evolution and promote .OH production. Under certain operating parameters, the electrode could efficiently remove enoxacin.

CHEMOSPHERE (2022)

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Article Chemistry, Multidisciplinary

Engineered extracellular vesicles and their mimetics for cancer immunotherapy

Chunping Liu et al.

Summary: Extracellular vesicles (EVs) are membranous vesicles secreted by living cells, serving as intermediaries for intercellular communication and molecular transfer. Recent studies have shown that EVs can regulate tumor occurrence and development by transferring molecules and have broad application prospects in immunotherapy. The breakthrough of nanotechnology promotes the development and exploration of engineered EVs for immune-targeted therapy.

JOURNAL OF CONTROLLED RELEASE (2022)

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Article Clinical Neurology

Transcranial alternating current stimulation for treating depression: a randomized controlled trial

Hongxing Wang et al.

Summary: In a randomized, double-blind controlled trial, Wang et al. demonstrate that four weeks of treatment with transcranial alternating current stimulation (tACS) is more effective in reducing symptoms compared to sham stimulation in first-episode drug-naive patients with major depressive disorder.

BRAIN (2022)

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Article Medicine, Research & Experimental

Pan-cancer analysis and experiments with cell lines reveal that the slightly elevated expression of DLGAP5 is involved in clear cell renal cell carcinoma progression

Yun Feng et al.

Summary: DLGAP5 is upregulated in various cancers, including ccRCC, and its expression is positively correlated with immune infiltration levels in ccRCC. Elevated DLGAP5 expression is associated with ccRCC progression and may serve as a prognostic risk factor, but not an independent one.

LIFE SCIENCES (2021)

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Review Medicine, Research & Experimental

Development of Hydrogels with Self-Healing Properties for Delivery of Bioactive Agents

Wing-Fu Lai

Summary: Hydrogels are soft materials used for bioactive agent delivery, but their high water content often results in poor mechanical strength. Researchers are exploring the design of self-healing hydrogel carriers to minimize structural damage during the release of bioactive agents.

MOLECULAR PHARMACEUTICS (2021)

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Article Physics, Multidisciplinary

Computational study of blood flow characteristics on formation of the aneurysm in internal carotid artery

Xiao-Yong Shen et al.

Summary: The study utilized computational simulations to uncover the effects of blood flow characteristics on the evolution and rupture of aneurysms in the internal carotid artery. The research aimed to identify the main causes for aneurysm rupture and pinpoint high-risk regions on the aneurysm wall. Findings suggest that aneurysm growth is directly related to its orientation and location, with internal wall shear stress being significantly lower than external stress.

EUROPEAN PHYSICAL JOURNAL PLUS (2021)

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Article Computer Science, Interdisciplinary Applications

Effects of blood flow characteristics on rupture of cerebral aneurysm: Computational study

Xiao-Yong Shen et al.

Summary: Cardiovascular disease and stroke have been identified as the leading causes of high death rates in recent decades, with irregular blood flow being a major factor. The study reveals that blood viscosity and velocity have a significant impact on the blood flow inside an aneurysm, with high velocity and viscosity increasing the risk of aneurysm rupture.

INTERNATIONAL JOURNAL OF MODERN PHYSICS C (2021)

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Article Pharmacology & Pharmacy

Property-Tuneable Microgels Fabricated by Using Flow-Focusing Microfluidic Geometry for Bioactive Agent Delivery

Wing-Fu Lai et al.

Summary: This study explores the use of Gelatine Methacryloyl (GM) in fabricating microgels for bioactive agent delivery. The microfluidic approach used in this study generates highly monodisperse microgels with tunable size. Tetracycline hydrochloride was used as a model agent to demonstrate prolonged release capabilities of the microgels, which showed potential for applications in food and pharmaceutical industries.

PHARMACEUTICS (2021)

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Review Pharmacology & Pharmacy