期刊
MATERIALS
卷 15, 期 24, 页码 -出版社
MDPI
DOI: 10.3390/ma15249057
关键词
fluorescent nanomaterials; carbon dots; Y-CDs; cell imaging probe
Carbon dots, as novel fluorescent nanomaterials, have gained significant research attention for their simple synthesis, robust fluorescence, low toxicity, and easy functionalization. This study successfully prepared nitrogen-doped yellow fluorescent nano-carbon dots (Y-CDs) with high quantum yield and photostability. The Y-CDs demonstrated effective cobalamin detection and were used as imaging probes for MDA-MB-231 cells.
As novel fluorescent nanomaterials, carbon dots have attracted increasing research attention because of their simple synthesis, robust fluorescence, low toxicity, and easy functionalisation. Previous research was focused on preparing carbon dots from biomass and chemical materials; however, most of these carbon dots exhibited blue fluorescence. Moreover, the fluorescence quantum yield was generally low, significantly limiting their application in biological imaging. To broaden the application scope of carbon dots, this study prepared long-wavelength emitting nano-carbon dots that exhibited increased quantum yield. Novel N-doped yellow fluorescent nano-carbon dots (Y-CDs) were synthesised via a hydrothermal method using L-tartaric acid and urea as the precursors. The Y-CDs had a high quantum yield (15.9%) and demonstrated photostability at various pHs, temperatures, and ionic strengths. The Y-CDs could detect cobalamin effectively and selectively, showing a linear relationship between fluorescence intensity and cobalamin concentration. The related coefficient was 0.997, and the detection limit was 2.101 mu mol/L. In addition, the Y-CDs were successfully used as an imaging probe for MDA-MB-231 cells. Therefore, the Y-CDs developed in this study can be used for cobalamin detection and cell imaging.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据