3.8 Article

An Overview of Laboratory Diagnosis of Central Nervous System Viral Infections

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Public, Environmental & Occupational Health

Metagenomic Next-Generation Sequencing vs. Traditional Microbiological Tests for Diagnosing Varicella-Zoster Virus Central Nervous System Infection

Yunqi Zhu et al.

Summary: This study suggests that CSF mNGS may have higher sensitivity for VZV detection than CSF VZV PCR and antibody tests, and has the advantage of identifying unexpected pathogens.

FRONTIERS IN PUBLIC HEALTH (2022)

Article Multidisciplinary Sciences

Integrating central nervous system metagenomics and host response for diagnosis of tuberculosis meningitis and its mimics

P. S. Ramachandran et al.

Summary: In this study, the authors combined metagenomics-based pathogen detection with a machine learning classifier based on host gene expression to enhance the diagnosis of tuberculous meningitis (TBM). By integrating these approaches, they achieved high sensitivity and specificity for detecting TBM and its mimics, even in low resource settings.

NATURE COMMUNICATIONS (2022)

Article Veterinary Sciences

Rapid Differential Detection of Japanese Encephalitis Virus and Getah Virus in Pigs or Mosquitos by a Duplex TaqMan Real-Time RT-PCR Assay

Yan Zhang et al.

Summary: A new duplex TaqMan RT-qPCR method for rapid identification and detection of Japanese encephalitis virus (JEV) and Getah virus (GETV) was established in this study. The method showed high sensitivity, extreme specificity, and excellent repeatability, and could be completed in a short time. It provided an effective tool for the detection and differentiation of JEV and GETV.

FRONTIERS IN VETERINARY SCIENCE (2022)

Review Pediatrics

Progress in the application of metagenomic next-generation sequencing in pediatric infectious diseases

Chi Li et al.

Summary: This article introduces the application of metagenomic next-generation sequencing (mNGS) technology in the diagnosis and treatment of neonatal and puerile infectious diseases, providing some examples.

PEDIATRICS AND NEONATOLOGY (2022)

Article Pathology

Viral metagenomic sequencing in the diagnosis of meningoencephalitis: a review of technical advances and diagnostic yield

Ellen C. Carbo et al.

Summary: Recent advances in metagenomics testing methodologies, both wet and dry lab, have provided additional etiological findings for meningoencephalitis patients. However, the diagnostic yield of metagenomic sequencing as a secondary test remains unknown. The current established infrastructure for bioinformatic analysis of SARS-CoV-2 may pave the way for global use of clinical metagenomics.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2021)

Article Immunology

Metagenomic Next-Generation Sequencing for Pathogen Detection and Transcriptomic Analysis in Pediatric Central Nervous System Infections

Nanda Ramchandar et al.

Summary: Pediatric CNS infections are potentially life-threatening and traditional testing methods may not always identify the causative pathogen. This study showed that metagenomic sequencing of CSF has the potential to rapidly and accurately identify pathogens, providing a promising diagnostic tool for children with CNS infections.

OPEN FORUM INFECTIOUS DISEASES (2021)

Review Biotechnology & Applied Microbiology

Advances and insights in the diagnosis of viral infections

Julija Dronina et al.

Summary: Viral infections are a common global healthcare issue, with lack of medical equipment and facilities during pandemics posing challenges. Detection of viral infections involves three approaches: direct virus detection, antibody testing, and observation of disease symptoms.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Review Biochemistry & Molecular Biology

Virus Detection: A Review of the Current and Emerging Molecular and Immunological Methods

A. Cassedy et al.

Summary: Viruses are prevalent in the environment, with some being major pathogens. Rapid diagnostic measures like nucleic acid detection and immunoassay methods are crucial for identifying viral infections quickly. Each method has its own advantages and limitations, highlighting the importance of choosing the right approach based on the specific requirements.

FRONTIERS IN MOLECULAR BIOSCIENCES (2021)

Article Infectious Diseases

Clinical usefulness of metagenomic next-generation sequencing for the diagnosis of central nervous system infection in people living with HIV

Jun Chen et al.

Summary: The clinical utility of metagenomic next-generation sequencing (mNGS) for diagnosing central nervous system (CNS) infection in people living with human immunodeficiency virus (PLWH) was evaluated in this study. Results showed that mNGS is a useful tool for diagnosing CNS infection among PLWH and led to modifications in treatment plans for some patients. Further investigations are needed to improve the sensitivity of mNGS in diagnosing CNS infections.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

Article Microbiology

Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis

Anne Piantadosi et al.

Summary: Metagenomic next-generation sequencing (mNGS) technology can assist in detecting multiple pathogens simultaneously, aiding in the diagnosis of neurological infections. In the study, this technique successfully identified pathogen nucleic acid in certain cases and helped uncover pathogens in cases that were clinically undiagnosed by traditional methods.
Article Chemistry, Multidisciplinary

Determination of Advantages and Limitations of qPCR Duplexing in a Single Fluorescent Channel

Haoqing Zhang et al.

Summary: This study introduced a single-channel qPCR duplexing method using EvaGreen intercalating dye and FAM probe, offering a cost-effective alternative to probe-based qPCR. The method demonstrated the ability to determine detectable concentration ratios of targets and eliminate fluorescence overspilling, while confirming PCR product specificity through melting curve analysis. The approach was validated on a commercial thermal cycler, increasing its utility for researchers in need of a practical and economical molecular diagnostics tool.

ACS OMEGA (2021)

Article Tropical Medicine

Characteristics and biomarkers of patients with central nervous system infection admitted to a referral hospital in Northern Vietnam

Cuong Chi Ngo et al.

Summary: This study used molecular assays to determine the causes of meningitis in adult patients, identifying various pathogens including Mycobacterium tuberculosis. Rural residence and elevated cerebrospinal fluid adenosine deaminase levels were associated with bacterial and tubercular meningitis.

TROPICAL MEDICINE AND HEALTH (2021)

Article Immunology

Viral Metagenomic Analysis of Cerebrospinal Fluid from Patients with Acute Central Nervous System Infections of Unknown Origin, Vietnam

Nguyen To Anh et al.

Summary: The study utilized metagenomic next-generation sequencing to detect various viruses in cerebrospinal fluid (CSF) samples from patients with acute CNS infection in Vietnamese hospitals. Enteroviruses were found to be the most common type of viruses detected in the study.

EMERGING INFECTIOUS DISEASES (2021)

Review Biochemistry & Molecular Biology

Developments, applications, and prospects of cryo-electron microscopy

Xu Benjin et al.

PROTEIN SCIENCE (2020)

Review Pharmacology & Pharmacy

Recent advances and perspectives of nucleic acid detection for coronavirus

Minzhe Shen et al.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2020)

Article Medicine, Research & Experimental

Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection

Yi Zhang et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2020)

Article Biochemical Research Methods

Improved detection of dengue and Zika viruses using multiplex RT-qPCR assays

Tey Putita Ou et al.

JOURNAL OF VIROLOGICAL METHODS (2020)

Review Clinical Neurology

Metagenomics for neurological infections - expanding our imagination

Prashanth S. Ramachandran et al.

NATURE REVIEWS NEUROLOGY (2020)

Article Multidisciplinary Sciences

A metagenomics-based diagnostic approach for central nervous system infections in hospital acute care setting

Mohammad Rubayet Hasan et al.

SCIENTIFIC REPORTS (2020)

Article Multidisciplinary Sciences

Next-generation sequencing in the diagnosis of viral encephalitis: sensitivity and clinical limitations

Karol Perlejewski et al.

SCIENTIFIC REPORTS (2020)

Editorial Material Radiology, Nuclear Medicine & Medical Imaging

Common infectious diseases of the central nervous systemc-linical features and imaging characteristics

Shan Li et al.

QUANTITATIVE IMAGING IN MEDICINE AND SURGERY (2020)

Review Microbiology

Molecular and Immunological Diagnostic Techniques of Medical Viruses

Daniel Hussien Reta et al.

INTERNATIONAL JOURNAL OF MICROBIOLOGY (2020)

Article Biochemical Research Methods

Prospective evaluation of diagnostic tools for respiratory viruses in children and adults

L. Busson et al.

JOURNAL OF VIROLOGICAL METHODS (2019)

Article Virology

Optimization of qRT-PCR assay for zika virus detection in human serum and urine

Maria del Pilar Martinez Viedma et al.

VIRUS RESEARCH (2019)

Article Medicine, General & Internal

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis

M. R. Wilson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Virology

Crystal Structure of the Japanese Encephalitis Virus Capsid Protein

Thanalai Poonsiri et al.

VIRUSES-BASEL (2019)

Editorial Material Biotechnology & Applied Microbiology

Electron microscopy in human diseases: diagnostic and research perspectives

Manuel Scimeca et al.

NANOMEDICINE (2019)

Review Microbiology

Electron Microscopy Methods for Virus Diagnosis and High Resolution Analysis of Viruses

Katja R. Richert-Poeggeler et al.

FRONTIERS IN MICROBIOLOGY (2019)

Article Medical Laboratory Technology

DNA Extraction and Polymerase Chain Reaction

Nalini Gupta

JOURNAL OF CYTOLOGY (2019)

Review Chemistry, Medicinal

Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites

Seiichi Sakamoto et al.

JOURNAL OF NATURAL MEDICINES (2018)

Article Medicine, General & Internal

Acute encephalitis - diagnosis and management

Mark Ellul et al.

CLINICAL MEDICINE (2018)

Article Clinical Neurology

Diagnostic Testing of Neurologic Infections

Prashanth S. Ramachandran et al.

NEUROLOGIC CLINICS (2018)

Article Multidisciplinary Sciences

Detection of central nervous system viral infections in adults in Manado, North Sulawesi, Indonesia

Arthur H. P. Mawuntu et al.

PLOS ONE (2018)

Review Microbiology

Metagenomics: The Next Culture-Independent Game Changer

Jessica D. Forbes et al.

FRONTIERS IN MICROBIOLOGY (2017)

Article Multidisciplinary Sciences

An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers

Lukas Kaufmann et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2017)

Review Biochemistry & Molecular Biology

Diseases and Molecular Diagnostics: A Step Closer to Precision Medicine

Shailendra Dwivedi et al.

INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2017)

Article Medical Laboratory Technology

Validation of Metagenomic Next-Generation Sequencing Tests for Universal Pathogen Detection

Robert Schlaberg et al.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE (2017)

Article Clinical Neurology

Management of Viral Central Nervous System Infections: A Primer for Clinicians

P. Brandon Bookstaver et al.

JOURNAL OF CENTRAL NERVOUS SYSTEM DISEASE (2017)

Article Emergency Medicine

Diagnosis and Treatment of Central Nervous System Infections in the Emergency Department

Maia Dorsett et al.

EMERGENCY MEDICINE CLINICS OF NORTH AMERICA (2016)

Article Infectious Diseases

Simultaneous detection of 13 viruses involved in meningoencephalitis using a newly developed multiplex PCR Mag-array system

Xiaodan Shi et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2016)

Article Parasitology

Western Blot Detection of Human Anti-Chikungunya Virus Antibody with Recombinant Envelope 2 Protein

Zhaoshou Yang et al.

KOREAN JOURNAL OF PARASITOLOGY (2016)

Review Infectious Diseases

Laboratory Diagnosis of Central Nervous System Infection

Taojun He et al.

CURRENT INFECTIOUS DISEASE REPORTS (2016)

Review Medical Laboratory Technology

Real-time PCR detection chemistry

E. Navarro et al.

CLINICA CHIMICA ACTA (2015)

Review Oncology

Molecular biology, pathogenesis and pathology of mumps virus

Steven Rubin et al.

JOURNAL OF PATHOLOGY (2015)

Article Multidisciplinary Sciences

The global distribution and burden of dengue

Samir Bhatt et al.

NATURE (2013)

Article Microbiology

Subtyping Influenza A Virus with Monoclonal Antibodies and an Indirect Immunofluorescence Assay

Jennifer Johnson et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2012)

Article Medicine, General & Internal

A New Phlebovirus Associated with Severe Febrile Illness in Missouri

Laura K. McMullan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Multidisciplinary Sciences

Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies

Todd C. Lorenz

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2012)

Article Medicine, General & Internal

Saliva Polymerase-Chain-Reaction Assay for Cytomegalovirus Screening in Newborns

Suresh B. Boppana et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Public, Environmental & Occupational Health

Comparison of Direct Fluorescence Assay and Real-Time RT-PCR as Diagnostics for Respiratory Syncytial Virus in Young Children

Caroline F. Shafik et al.

JOURNAL OF TROPICAL MEDICINE (2011)

Article Immunology

Novel Human Reovirus Isolated from Children with Acute Necrotizing Encephalopathy

Louise A. Ouattara et al.

EMERGING INFECTIOUS DISEASES (2011)

Review Biotechnology & Applied Microbiology

The Role of Electron Microscopy in the Rapid Diagnosis of Viral Infections - review

J. Schramlova et al.

FOLIA MICROBIOLOGICA (2010)

Article Biochemical Research Methods

Development of a multiplex polymerase chain reaction assay for simultaneous identification of human enterovirus 71 and coxsackievirus A16

Nguyen Thi Thanh Thao et al.

JOURNAL OF VIROLOGICAL METHODS (2010)

Review Immunology

Measles virus infection of the CNS: human disease, animal models, and approaches to therapy

Dajana Reuter et al.

MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2010)

Review Microbiology

Modern Uses of Electron Microscopy for Detection of Viruses

Cynthia S. Goldsmith et al.

CLINICAL MICROBIOLOGY REVIEWS (2009)

Article Medical Laboratory Technology

Developments in Immunologic Assays for Respiratory Viruses

Marie Louise Landry

CLINICS IN LABORATORY MEDICINE (2009)

Review Microbiology

Role of cell culture for virus detection in the age of technology

Diane S. Leland et al.

CLINICAL MICROBIOLOGY REVIEWS (2007)

Article Medicine, General & Internal

Transmission of lymphocytic choriomeningitis virus by organ transplantation.

Staci A. Fischer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Review Microbiology

Molecular methods for diagnosis of viral encephalitis

RL DeBiasi et al.

CLINICAL MICROBIOLOGY REVIEWS (2004)

Article Infectious Diseases

Evaluation of the ELVIS plate method for the detection and typing of herpes simplex virus in clinical specimens

GA Crist et al.

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2004)

Article Virology

Control of central nervous system viral persistence by neutralizing antibody

C Ramakrishna et al.

JOURNAL OF VIROLOGY (2003)

Article Virology

Diagnosis of Nipah virus encephalitis by electron microscopy of cerebrospinal fluid

VTK Chow et al.

JOURNAL OF CLINICAL VIROLOGY (2000)