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Alex Bateman et al.
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Botao Pan et al.
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Sabri Hamad et al.
BIOINFORMATICS (2019)
ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway
Bo Chu et al.
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Antoine Daina et al.
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Domenico Gadaleta et al.
JOURNAL OF CHEMINFORMATICS (2019)
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Inmaculada Garcia-Ruiz et al.
REDOX BIOLOGY (2019)
NQO1 potentiates apoptosis evasion and upregulates XIAP via inhibiting proteasome-mediated degradation SIRT6 in hepatocellular carcinoma
Hong-Zhong Zhou et al.
CELL COMMUNICATION AND SIGNALING (2019)
Network pharmacology-based prediction of the active ingredients, potential targets, and signaling pathways in compound Lian-Ge granules for treatment of diabetes
Jintao Xue et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Polypharmacology Browser PPB2: Target Prediction Combining Nearest Neighbors with Machine Learning
Mahendra Awale et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2019)
SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping
Yang Wu et al.
NUCLEIC ACIDS RESEARCH (2019)
ChEMBL: towards direct deposition of bioassay data
David Mendez et al.
NUCLEIC ACIDS RESEARCH (2019)
TCMID 2.0: a comprehensive resource for TCM
Lin Huang et al.
NUCLEIC ACIDS RESEARCH (2018)
DrugBank 5.0: a major update to the DrugBank database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
CBR1 rs9024 genotype status impacts the bioactivation of loxoprofen in human liver
Adolfo Quinones-Lombrana et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2018)
Unexplored therapeutic opportunities in the human genome
Tudor I. Oprea et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
ADMETlab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database
Jie Dong et al.
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Erzhi Pill® Protected Experimental Liver Injury Against Apoptosis via the PI3K/Akt/Raptor/Rictor Pathway
Hai-Mei Zhao et al.
FRONTIERS IN PHARMACOLOGY (2018)
HSP90AA1-mediated autophagy promotes drug resistance in osteosarcoma
Xin Xiao et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
KEGG: new perspectives on genomes, pathways, diseases and drugs
Minoru Kanehisa et al.
NUCLEIC ACIDS RESEARCH (2017)
Effects of aqueous extracts of Ecliptae herba, Polygoni multiflori radix praeparata and Rehmanniae radix praeparata on melanogenesis and the migration of human melanocytes
Ping Xu et al.
JOURNAL OF ETHNOPHARMACOLOGY (2017)
Comparative analysis of chemical similarity methods for modular natural products with a hypothetical structure enumeration algorithm
Michael A. Skinnider et al.
JOURNAL OF CHEMINFORMATICS (2017)
The polypharmacology browser: a web-based multi-fingerprint target prediction tool using ChEMBL bioactivity data
Mahendra Awale et al.
JOURNAL OF CHEMINFORMATICS (2017)
ADME properties evaluation in drug discovery: Prediction of plasma protein binding using NSGA-II combining PLS and consensus modeling
Ning-Ning Wang et al.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS (2017)
An analysis of FDA-approved drugs: natural products and their derivatives
Eric Patridge et al.
DRUG DISCOVERY TODAY (2016)
ADME Properties Evaluation in Drug Discovery: Prediction of Caco-2 Cell Permeability Using a Combination of NSGA-II and Boosting
Ning-Ning Wang et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2016)
Natural Products as Sources of New Drugs from 1981 to 2014
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2016)
ClassyFire: automated chemical classification with a comprehensive, computable taxonomy
Yannick Djoumbou Feunang et al.
JOURNAL OF CHEMINFORMATICS (2016)
Synergistic Effects of Chinese Herbal Medicine: A Comprehensive Review of Methodology and Current Research
Xian Zhou et al.
FRONTIERS IN PHARMACOLOGY (2016)
Revealing the Macromolecular Targets of Fragment-Like Natural Products
Tiago Rodrigues et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
PUG-SOAP and PUG-REST: web services for programmatic access to chemical information in PubChem
Sunghwan Kim et al.
NUCLEIC ACIDS RESEARCH (2015)
ChEMBL web services: streamlining access to drug discovery data and utilities
Mark Davies et al.
NUCLEIC ACIDS RESEARCH (2015)
The Advances in Research on the Pharmacological Effects of Fructus Ligustri Lucidi
Zunting Pang et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Ligustri Lucidi Fructus as a traditional Chinese medicine: a review of its phytochemistry and pharmacology
Liangliang Gao et al.
NATURAL PRODUCT RESEARCH (2015)
A Network Pharmacology Approach to Determine Active Compounds and Action Mechanisms of Ge-Gen-Qin-Lian Decoction for Treatment of Type 2 Diabetes
Huiying Li et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
Revealing the macromolecular targets of complex natural products
Daniel Reker et al.
NATURE CHEMISTRY (2014)
TCMSP: a database of systems pharmacology for drug discovery from herbal medicines
Jinlong Ru et al.
JOURNAL OF CHEMINFORMATICS (2014)
HIT: linking herbal active ingredients to targets
Hao Ye et al.
NUCLEIC ACIDS RESEARCH (2011)
TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico
Calvin Yu-Chian Chen
PLOS ONE (2011)
Scaffold Hopping Using Two-Dimensional Fingerprints: True Potential, Black Magic, or a Hopeless Endeavor? Guidelines for Virtual Screening
Martin Vogt et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Da Wei Huang et al.
NATURE PROTOCOLS (2009)
Relating protein pharmacology by ligand chemistry
Michael J. Keiser et al.
NATURE BIOTECHNOLOGY (2007)
The evolving role of natural products in drug discovery
FE Koehn et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Cytoscape: A software environment for integrated models of biomolecular interaction networks
P Shannon et al.
GENOME RESEARCH (2003)